UNC45B (NM_173167) Human Untagged Clone

CAT#: SC306792

UNC45B (untagged)-Human unc-45 homolog B (C. elegans) (UNC45B), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: UNC45B
• Synonyms: CMYA4; CTRCT43; SMUNC45; UNC-45B; UNC45
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_173167 edited
  ATGGCAGAGGTGGAAGCGGTACAGCTGAAGGAGGAAGGAAACCGGCATTTCCAGCTCCAG
  GACTACAAGGCCGCCACAAATAGCTACAGCCAGGCCCTGAAGCTGACCAAGGACAAGGCC
  CTGCTGGCCACGCTTTATCGGAACCGGGCAGCCTGTGGCCTGAAAACGGAGAGCTACATC
  CAGGCAGCTTCAGATGCCTCCAGAGCCATCGACATCAACTCCTCGGACATCAAGGCTCTG
  TATCGGCGATGCCAGGCACTGGAGCACCTGGGGAAGCTGGACCAGGCCTTCAAAGACGTG
  CAGCGTTGTGCCACCCTCGAGCCACGGAACCAGAACTTCCAGGAGATGCTGAGGAGACTC
  AACACCAGCATTCAGGAGAAGCTCCGAGTGCAGTTCTCCACAGACTCGAGGGTACAGAAG
  ATGTTTGAGATCCTCTTGGATGAAAACAGTGAGGCTGATAAGCGGGAAAAGGCTGCCAAC
  AATCTCATTGTCCTAGGCCGTGAGGAAGCAGGGGCTGAGAAGATCTTCCAGAACAATGGA
  GTAGCCTTGCTACTGCAGCTTCTGGACACTAAGAAGCCTGAGCTGGTGCTGGCTGCAGTG
  CGGACCCTGTCGGGCATGTGCAGCGGCCACCAAGCCAGAGCCACAGTGATTCTGCATGCA
  GTGCGGATAGACCGAATCTGTAGCCTCATGGCCGTGGAGAATGAGGAGATGTCTCTGGCT
  GTCTGCAACCTGCTCCAAGCCATCATTGACTCCTTGTCTGGGGAGGACAAGCGGGAGCAT
  CGAGGGAAGGAGGAGGCCCTGGTTCTAGACACCAAGAAGGACCTGAAGCAGATCACCAGC
  CACCTGCTGGACATGCTAGTCAGCAAGAAGGTGTCTGGCCAGGGCAGGGATCAGGCGCTG
  AACCTGCTCAATAAGAATGTTCCCAGGAAGGACCTTGCCATTCATGACAACTCACGTACC
  ATCTATGTGGTGGATAATGGTCTGAGGAAGATCCTGAAGGTTGTGGGGCAGGTTCCAGAT
  CTGCCATCCTGCCTGCCCCTGACTGACAACACCCGCATGCTGGCCTCTATCCTCATCAAC
  AAGCTCTATGATGACCTGCGCTGTGACCCGGAGCGCGATCACTTCCGCAAGATCTGTGAG
  GAATATATCACGGGCAAGTTTGACCCCCAGGACATGGACAAGAACTTGAATGCCATCCAG
  ACAGTGTCAGGGATCCTGCAGGGCCCCTTTGACCTGGGCAACCAGCTGCTGGGACTGAAA
  GGTGTGATGGAGATGATGGTGGCACTATGTGGCTCAGAGCGCGAGACGGACCAGCTGGTG
  GCCGTGGAGGCCCTCATCCATGCCTCCACGAAGCTCAGCCGCGCCACCTTCATCATCACC
  AATGGAGTGTCACTGCTCAAACAGATCTACAAGACCACCAAAAATGAGAAGATCAAGATC
  CGCACACTGGTGGGACTCTGTAAGCTCGGCTCTGCAGGTGGCACAGACTACGGTCTCAGG
  CAGTTTGCGGAAGGGTCGACAGAAAAACTGGCCAAACAGTGTCGCAAGTGGCTGTGCAAT
  ATGTCCATAGACACTCGGACCCGACGCTGGGCAGTGGAGGGCCTGGCCTACCTCACGCTG
  GACGCTGATGTGAAGGACGACTTTGTCCAGGACGTCCCTGCCCTGCAGGCCATGTTTGAG
  CTGGCCAAG::::::ACCAGTGACAAGACCATCCTGTACTCGGTGGCCACCACCCTGGTG
  AACTGCACCAACAGCTACGATGTCAAGGAGGTCATCCCAGAGCTTGTCCAGCTCGCCAAG
  TTCTCCAAGCAGCATGTGCCCGAGGAACACCCCAAGGACAAGAAGGACTTTATAGACATG
  CGGGTGAAGCGGCTTCTGAAGGCGGGTGTCATCTCTGCCCTGGCTTGCATGGTGAAAGCA
  GATAGTGCCATCCTCACTGACCAGACCAAGGAGCTGCTGGCCAGGGTATTCCTGGCACTG
  TGTGACAACCCAAAGGACCGAGGCACCATTGTGGCTCAAGGTGGTGGCAAGGCCCTGATT
  CCCCTGGCTTTGGAGGGCACAGATGTGGGCAAGGTGAAGGCAGCCCACGCTCTAGCAAAG
  ATCGCTGCTGTCTCCAATCCGGACATTGCTTTTCCTGGGGAGCGGGTGTATGAGGTGGTG
  CGGCCCCTTGTAAGACTCTTGGACACACAGAGGGATGGGCTTCAGAACTATGAGGCTCTC
  CTAGGCCTCACCAACCTGTCTGGGCGGAGTGACAAACTCCGGCAGAAGATCTTTAAGGAG
  AGGGCCTTGCCAGACATCGAGAACTACATGTTTGAGAATCATGATCAGCTGCGGCAGGCG
  GCCACCGAGTGCATGTGCAACATGGTGCTCCACAAGGAGGTACAGGAAAGGTTCTTGGCT
  GACGGGAATGACCGGCTGAAGCTGGTGGTGCTGCTCTGCGGGGAGGATGATGATAAGGTG
  CAGAATGCGGCTGCAGGGGCTCTGGCCATGCTGACAGCAGCACACAAGAAACTGTGCCTC
  AAGATGACTCAAGTGACAACCCAGTGGTTGGAGATCCTCCAGCGGCTTTGCCTGCACGAC
  CAGCTGTCTGTCCAACACCGGGGCCTGGTCATTGCCTACAACCTACTGGCAGCCGATGCT
  GAGCTGGCCAAGAAGCTGGTGGAGAGTGAGCTGCTGGAGATCCTGACTGTGGTGGGCAAA
  CAGGAGCCAGATGAGAAGAAGGCAGAAGTGGTTCAGACAGCCCGAGAATGTCTCATCAAG
  TGCATGGATTATGGTTTCATTAAACCAGTGTCTTAG
  
• Restriction Sites: Please inquire
• ACCN: NM_173167
• ORF Size: 2796 bp
• Insert Size: 2800
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to differ from the protein associated to this reference by three amino acids.

Reference Data

• RefSeq: NM_173167.2, NP_775259.1
• RefSeq Size: 5694
• RefSeq ORF: 2796
• Locus ID: 146862
• Gene Summary: This gene encodes a co-chaperone required for folding and accumulation of type II myosins. The protein consists of three tetratricopeptide repeat motifs at the N-terminus that form a complex with heat shock protein 90, a central region of unknown function that is conserved in all Unc-45 proteins, and a C-terminal Unc-45/Cro1/She4 domain. The protein is expressed at high levels in striated muscle, where its muscle myosin chaperone activity is dependent on heat shock protein 90 acting as a co-chaperone. A missense mutation in this gene has been associated with cataract development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
  Transcript Variant: This variant (1) encodes the longest isoform (1).