Leucyl cystinyl aminopeptidase (LNPEP) (NM_175920) Human Untagged Clone

CAT#: SC307057

LNPEP (untagged)-Human leucyl/cystinyl aminopeptidase (LNPEP), transcript variant 2


  "NM_175920" in other vectors (4)

Reconstitution Protocol

USD 2,040.00

6 Weeks*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol LNPEP
Synonyms CAP; IRAP; P-LAP; PLAP
Vector pCMV6 series
Sequence Data
>NCBI ORF sequence for NM_175920, the custom clone sequence may differ by one or more nucleotides
ATGATTGAAAACAGCATGTTTGAGGAAGAACCAGATGTGGTGGATTTAGCCAAAGAGCCT
TGTTTACATCCTCTAGAGCCTGATGAGGTGGAATATGAGCCCCGGGGTTCCCGACTGCTG
GTGCGGGGTCTTGGTGAGCATGAGATGGAGGAGGATGAAGAGGATTATGAGTCATCAGCA
AAGCTGCTGGGCATGTCCTTCATGAATAGAAGCTCAGGCCTTCGGAACAGTGCAACTGGT
TACAGGCAGAGCCCAGATGGGGCTTGTTCAGTACCCTCTGCAAGGACCATGGTGGTCTGT
GCTTTTGTCATCGTGGTTGCTGTTTCTGTAATCATGGTGATTTACTTACTGCCCAGATGT
ACCTTTACCAAAGAAGGCTGCCATAAAAAAAACCAGTCAATTGGACTAATTCAGCCATTT
GCAACAAATGGGAAATTGTTTCCATGGGCACAGATCAGGCTTCCCACTGCCGTTGTGCCA
CTACGCTATGAACTCAGCCTACACCCGAACCTAACCTCGATGACATTCAGGGGTTCTGTG
ACAATTTCAGTTCAGGCTCTTCAGGTCACATGGAATATCATTCTTCATAGCACAGGTCAT
AATATTTCAAGAGTGACCTTTATGTCAGCAGTTTCAAGCCAAGAAAAACAAGCTGAGATC
CTGGAATATGCATATCATGGACAGATCGCCATTGTTGCCCCCGAAGCCCTTCTAGCAGGG
CACAATTATACGTTGAAGATAGAGTACTCGGCAAATATATCTAGTTCTTATTATGGGTTT
TATGGCTTCTCCTACACAGATGAAAGTAATGAGAAAAAGTACTTTGCAGCAACTCAGTTT
GAACCCCTGGCAGCAAGATCTGCTTTTCCTTGTTTTGATGAACCAGCATTTAAAGCCACT
TTTATCATCAAGATCATAAGGGATGAGCAATACACCGCTTTATCAAATATGCCTAAGAAG
TCATCAGTCGTTCTAGATGATGGACTTGTTCAGGATGAGTTTTCTGAGAGTGTGAAGATG
AGCACTTACTTGGTTGCTTTCATTGTGGGAGAGATGAAGAACCTGAGTCAGGACGTAAAT
GGAACCCTGGTTTCTATATATGCTGTACCAGAAAAGATTGGTCAAGTTCATTATGCCTTG
GAAACAACTGTGAAGCTTCTTGAGTTTTTTCAAAACTACTTTGAAATTCAGTACCCACTT
AAGAAATTGGATTTGGTGGCTATTCCTGACTTTGAAGCAGGAGCAATGGAAAATTGGGGT
TTGCTCACCTTCCGAGAGGAGACACTTCTGTATGACAGTAACACTTCTTCAATGGCGGAT
AGAAAGCTGGTGACTAAAATCATTGCTCATGAGCTGGCCCACCAGTGGTTTGGCAATCTG
GTAACAATGAAGTGGTGGAATGACCTATGGCTAAATGAAGGTTTTGCCACTTTCATGGAG
TATTTCTCTTTGGAAAAAATATTCAAAGAGCTTTCTAGTTATGAAGATTTCTTAGATGCT
CGATTTAAAACCATGAAGAAAGATTCCTTAAATTCATCTCATCCAATATCATCATCTGTT
CAGTCTTCAGAACAAATTGAAGAAATGTTTGATTCTCTTTCCTATTTTAAGGGATCTTCT
CTCTTGTTGATGTTGAAAACTTACCTTAGTGAAGATGTGTTTCAACATGCTGTTGTCCTT
TACCTGCATAATCACAGCTATGCATCTATTCAAAGTGATGATCTGTGGGATAGTTTTAAT
GAGGTCACAAACCAAACACTAGATGTAAAGAGAATGATGAAAACCTGGACCCTGCAGAAA
GGATTTCCTTTAGTGACTGTTCAAAAGAAAGGAAAGGAACTTTTTATACAACAAGAGAGA
TTCTTTTTAAATATGAAGCCTGAAATTCAGCCTTCAGATACAAGCTACCTGTGGCATATT
CCACTATCCTATGTCACTGAAGGAAGAAATTATTCAAAATATCAATCGGTATCATTACTG
GATAAGAAATCAGGTGTCATCAATCTTACAGAAGAAGTGCTGTGGGTCAAAGTGAATATA
AACATGAATGGTTATTATATTGTACACTATGCAGATGATGATTGGGAAGCACTAATCCAT
CAGTTGAAAATAAATCCTTATGTTCTGAGTGACAAAGACCGAGCCAACCTTATCAACAAC
ATCTTTGAACTTGCAGGCCTAGGCAAGGTACCTCTCAAGAGGGCCTTTGATTTGATTAAT
TATCTTGGAAATGAGAACCATACTGCACCCATCACCGAAGCCCTGTTTCAGACAGACCTC
ATCTATAACCTCCTTGAAAAACTGGGATACATGGATCTGGCCTCAAGACTGGTGACTAGG
GTATTTAAATTACTTCAAAACCAAATTCAACAACAAACTTGGACTGATGAGGGCACTCCA
TCTATGCGAGAGCTTCGGTCAGCCCTGCTAGAGTTTGCTTGCACCCACAACCTGGGGAAC
TGCTCTACTACTGCCATGAAACTGTTTGATGACTGGATGGCATCCAATGGAACTCAAAGC
CTACCTACTGATGTCATGACAACTGTGTTCAAAGTTGGAGCAAAAACTGACAAAGGCTGG
TCATTCCTTTTGGGCAAATACATTTCTATAGGCTCTGAAGCAGAGAAGAACAAAATACTA
GAAGCACTTGCCAGCTCAGAGGATGTGCGGAAGCTTTACTGGTTAATGAAAAGTAGCCTG
AATGGAGATAACTTCCGAACACAGAAGCTGTCTTTTATCATTAGAACAGTGGGTCGACAT
TTTCCTGGACACTTACTGGCATGGGATTTTGTCAAAGAGAACTGGAATAAGCTTGTACAG
AAGTTCCCTCTGGGGTCCTATACCATACAAAATATTGTTGCTGGATCAACTTACCTGTTT
TCAACAAAGACACATTTATCTGAGGTTCAGGCATTCTTTGAAAATCAGTCAGAGGCAACC
TTCCGGCTTCGTTGTGTCCAGGAGGCTTTGGAAGTCATTCAGTTGAATATCCAGTGGATG
GAGAAGAACCTCAAAAGTCTCACATGGTGGCTGTAG
Restriction Sites Please inquire     
ACCN NM_175920
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_175920.3, NP_787116.2
RefSeq Size 4262 bp
RefSeq ORF 3036 bp
Locus ID 4012
Cytogenetics 5q15
Protein Families Druggable Genome, Protease, Secreted Protein, Transmembrane
Protein Pathways Renin-angiotensin system
Gene Summary 'This gene encodes a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. The protein catalyzes the final step in the conversion of angiotensinogen to angiotensin IV (AT4) and is also a receptor for AT4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]'
Transcript Variant: This variant (2) contains an alternate 5' exon, which results in a distinct 5' UTR and use of a downstream start codon, compared to variant 1. The resulting isoform (2) has a shorter N-terminus when compared to isoform 1.

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.