PPAP2C (PLPP2) (NM_177543) Human Untagged Clone

CAT#: SC307107

PPAP2C (untagged)-Human phosphatidic acid phosphatase type 2C (PPAP2C), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PLPP2
• Synonyms: LPP2; PAP-2c; PAP2-g; PPAP2C
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_177543, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGGGGTCGCGAGAGGCCCGGGGAGCCGGGGCCAGCATCCCCCGCCCCGGCAGCAGGAAGTCTGTGCGG
  AGGGGCCGCGCGCGCGCCTCCATCCCGCCCCGCCTGGCCTGGGAGCCTCCCTGCCCTTCGCTATCCTGAC
  GCTGGTGAACGCCCCGTACAAGCGAGGATTTTACTGCGGGGATGACTCCATCCGGTACCCCTACCGTCCA
  GATACCATCACCCACGGGCTCATGGCTGGGGTCACCATCACGGCCACCGTCATCCTTGTCTCGGCCGGGG
  AAGCCTACCTGGTGTACACAGACCGGCTCTATTCTCGCTCGGACTTCAACAACTACGTGGCTGCTGTATA
  CAAGGTGCTGGGGACCTTCCTGTTTGGGGCTGCCGTGAGCCAGTCTCTGACAGACCTGGCCAAGTACATG
  ATTGGGCGTCTGAGGCCCAACTTCCTAGCCGTCTGCGACCCCGACTGGAGCCGGGTCAACTGCTCGGTCT
  ATGTGCAGCTGGAGAAGGTGTGCAGGGGAAACCCTGCTGATGTCACCGAGGCCAGGTTGTCTTTCTACTC
  GGGACACTCTTCCTTTGGGATGTACTGCATGGTGTTCTTGGCGCTGTATGTGCAGGCACGACTCTGTTGG
  AAGTGGGCACGGCTGCTGCGACCCACAGTCCAGTTCTTCCTGGTGGCCTTTGCCCTCTACGTGGGCTACA
  CCCGCGTGTCTGATTACAAACACCACTGGAGCGATGTCCTTGTTGGCCTCCTGCAGGGGGCACTGGTGGC
  TGCCCTCACTGTCTGCTACATCTCAGACTTCTTCAAAGCCCGACCCCCACAGCACTGTCTGAAGGAGGAG
  GAGCTGGAACGGAAGCCCAGCCTGTCACTGACGTTGACCCTGGGCGAGGCTGACCACAACCACTATGGAT
  ACCCGCACTCCTCCTCCTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_177543
• ORF Size: 930 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_177543.2, NP_808211.1
• RefSeq Size: 1387
• RefSeq ORF: 930
• Locus ID: 8612
• Protein Families: Druggable Genome, Stem cell - Pluripotency, Transmembrane
• Protein Pathways: Ether lipid metabolism, Fc gamma R-mediated phagocytosis, Glycerolipid metabolism, Glycerophospholipid metabolism, Metabolic pathways, Sphingolipid metabolism
• Gene Summary: The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is similar to phosphatidic acid phosphatase type 2A (PPAP2A) and type 2B (PPAP2B). All three proteins contain 6 transmembrane regions, and a consensus N-glycosylation site. This protein has been shown to possess membrane associated PAP activity. Three alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (3) encodes the longest isoform (3).