OTOP1 (NM_177998) Human Untagged Clone

CAT#: SC307118

OTOP1 (untagged)-Human otopetrin 1 (OTOP1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: OTOP1
• Synonyms: MGC163302; MGC163304
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_177998, the custom clone sequence may differ by one or more nucleotides
  ATGCTCGAGGGCCTGGGGTCGCCCGCCTCGCCCCGGGCAGCTGCAAGCGCCTCGGTCGCA
  GGGTCGTCGGGGCCAGCGGCCTGCTCGCCTCCCTCGTCCTCGGCCCCGAGGTCCCCGGAA
  TCCCCGGCCCCCCGGCGGGGCGGTGTGCGCGCCAGCGTCCCACAGAAACTGGCCGAGATG
  CTGAGCAGCCAGTATGGGCTGATCGTGTTCGTGGCGGGGCTGCTGCTGCTGCTGGCCTGG
  GCCGTGCACGCCGCGGGCGTGAGCAAGAGCGACCTGCTGTGCTTCCTGACGGCGCTCATG
  CTGCTGCAGCTGCTGTGGATGCTGTGGTACGTGGGCCGCAGCTCCGCGCACCGCCGCCTC
  TTCCGCCTCAAGGACACGCACGCGGGTGCCGGCTGGCTGCGCGGTAGTATCACATTGTTT
  GCAGTCATTACCGTCATCCTGGGATGCCTTAAAATTGGATACTTCATTGGATTTTCAGAA
  TGTTTATCAGCCACTGAAGGAGTTTTCCCAGTCACCCATTCAGTGCATACTTTGTTGCAG
  GTATATTTTCTTTGGGGGCATGCAAAGGATATTATCCAGTCTTTCAAAACACTGGAAAGG
  TTTGGAGTGATCCACTCGGTGTTCACCAACCTGCTTCTGTGGGCCAATGGCGTCCTCAAT
  GAGTCAAAGCACCAACTCAATGAGCACAAGGAACGGCTCATCACTCTGGGTTTTGGGAAC
  ATAACAACAGTTTTAGATGACCACACACCGCAGTGTAACTGCACGCCCCCAACTCTGTGC
  ACTGCCATCTCCCACGGGATCTACTACCTCTACCCCTTCAACATAGAGTATCAGATCCTG
  GCCTCCACAATGCTCTACGTCCTGTGGAAGAACATCGGGCGCAAAGTTGACAGCCATCAG
  CACCAGAAGATGCAGTTCAAGTCTGATGGGGTCATGGTGGGCGCAGTCCTGGGCCTGACC
  GTGCTGGCCGCCACCATTGCTGTGGTGGTGGTATACCTGATTCATATTGGGCGCTCCAAG
  ACCAAGAGCGAGTCGGCACTCATCATGTTCTACCTGTATGCCATCACCCTGCTGATGCTT
  ATGGGGGCTGCGGGGCTGGCTGGAATCCGGATTTACAGGATAGACGAGAAGTCACTGGAT
  GAGTCCAAAAATCCGGCCCGCAAACTGGACTCGGACCTCTTGGTGGGCACTGCCTCGGGC
  TCCTGGCTTATCTCCTGGGGCTCAATCTTGGCCATCCTCTGTGCTGAGGGCCACCCCCGC
  TACACCTGGTACAACCTGCCCTACTCCATCCTGGCGATCGTGGAGAAGTACATCCAGAAC
  CTCTTCATCTTTGAATCCATTCACCGAGAGCCTGAAAAACTCTCTGAGGACATCCAAACC
  CTTCGGGTGGTCACAGTCTGCAATGGCAACACCATGCCCCTTGCTTCTTCCTGCCCCAAG
  AGTGGAGGTGTGGCCAGAGATGTGGCTCCCCAGGGCAAGGACATGCCACCAGCAGCCAAT
  GGAAATGTGTGCATGAGAGAAAGCCATGACAAGGAGGAGGAGAAGCAGGAGGAGAGCAGC
  TGGGGAGGGAGCCCAAGCCCAGTCCGCCTTCCCCGTTTCTTACAGGGCAACGCCAAGAGA
  AAAGTCCTGAGGAATATTGCAGCCTTCTTGTTCCTCTGCAATATTTCGCTTTGGATACCT
  CCCGCCTTTGGCTGTCGACCTGAGTATGACAATGGATTGGAGGAGATTGTCTTTGGCTTT
  GAACCCTGGATAATTGTGGTCAACCTGGCCATGCCTTTTTCTATTTTCTATCGAATGCAC
  GCAGCTGCCTCCCTCTTTGAGGTCTATTGTAAGATATAG
  
• Restriction Sites: Please inquire
• ACCN: NM_177998
• ORF Size: 1839 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_177998.1, NP_819056.1
• RefSeq Size: 1869
• RefSeq ORF: 1839
• Locus ID: 133060
• Protein Families: Transmembrane
• Gene Summary: This gene encodes a transmembrane protein which belongs to the otopetrin domain protein family and is required for the formation of otoconia and otoliths, calcium carbonate biominerals within the inner ear of mammals that are required for the detection of linear acceleration and gravity. This gene modulates purinergic control of intracellular calcium in vestibular supporting cells. Naturally occurring mutations in the orthologous mouse gene are associated with nonsyndromic otoconia agenesis and a consequent balance defect. The orthologous mouse gene is also induced in white adipose tissue during obesity. The encoded protein is a component of a counterinflammatory pathway that attenuates obesity-induced adipose tissue inflammation and plays an adaptive role in maintaining metabolic homeostasis in obesity. [provided by RefSeq, Jul 2017]