CCDC50 (NM_178335) Human Untagged Clone

CAT#: SC307154

CCDC50 (untagged)-Human coiled-coil domain containing 50 (CCDC50), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CCDC50
• Synonyms: C3orf6; DFNA44; YMER
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_178335, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCTGAAGTCAGCATCGACCAGTCCAAGCTGCCTGGAGTCAAGGAAGTATGCCGAGATTTTGCTGTCC
  TGGAGGACCACACCCTGGCTCACAGCCTGCAGGAACAAGAGATTGAGCATCATTTGGCATCGAACGTTCA
  GCGGAACCGTTTGGTCCAGCATGATCTCCAGGTGGCTAAGCAGCTCCAAGAGGAAGATCTGAAAGCGCAG
  GCCCAGCTCCAGAAGCGCTACAAAGACCTTGAACAACAAGACTGTGAAATTGCTCAGGAAATTCAGGAGA
  AGCTGGCTATTGAGGCAGAGAGACGACGCATTCAGGAGAAGAAGGATGAGGACATAGCTCGCCTTTTGCA
  AGAAAAGGAGTTACAGGAAGAGAAAAAGAGAAAGAAACACTTTCCAGAGTTCCCTGCAACCCGTGCTTAT
  GCAGATAGTTACTATTATGAAGATGGAGACCAACCAGGGTCAAGGAGGGCCAGGGAATTGGGTTCTGGAT
  TCTCAAGACCTTGTAGACTCCAAAGAGATGGAAAGACTGTGAAGCACAAGAAAGAGAAACCAGAACATCC
  ACTGGAGAACTTGGAAGAGCCAGAACAACATTGTTCATCGAAGAGATCCCTGTCATCCTCTAGCTCGGGC
  AAAGGGAGGGACAATCCCCATATTAACAATGAGCAGCATGAAAGGAAACGGTCCACTCAGGAGAGGCCTC
  GGAGACCTCTGCTTCCCACGATCAGTGGTGAAGTGTTTCTGAGCACTGAATGTGATGACTGGGAGACTAA
  GATTAACCATCAGACTCGAAATTGGGAAAAACAGTCTCGACACCAAGATCGACTTTCACCCAAGTCCTCA
  CAAAAAGCAGGGCTTCACTGCAAGGAAGTTGTATATGGGAGGGACCATGGGCAAGGTGAGCACAGAAAAA
  GGAGACACAGGCCCAGGACTCCTCCATTCTCAGAGAGTGAGGAGCAGCTCCACCTCCATGACGCAGGAAT
  GAAGCCAAGAGTGATGAAAGAAGCTGTATCTACTCCATCACGAATGGCCCACAGGGATCAGGAATGGTAT
  GATGCTGAAATTGCCAGAAAACTGCAAGAAGAAGAACTTTTGGCTACCCAGGTGGACATGAGAGCCGCTC
  AAGTAGCTCAAGATGAAGAAATCGCTCGACTTCTAATGGCTGAAGAAAAGAAAGCTTACAAAAAAGCCAA
  GGAGCGGGAGAAATCATCTTTGGACAAAAGAAAGCAAGACCCCGAGTGGAAGCCAAAAACAGCTAAAGCA
  GCAAATTCCAAGTCAAAAGAGAGTGATGAACCTCACCATTCTAAGAATGAAAGGCCAGCACGGCCACCAC
  CACCTATCATGACAGATGGTGAAGATGCGGATTACACTCATTTTACAAACCAGCAGAGTTCCACACGGCA
  TTTCTCAAAATCAGAGTCCTCTCATAAAGGTTTTCATTACAAACATTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_178335
• ORF Size: 1449 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_178335.2, NP_848018.1
• RefSeq Size: 8949
• RefSeq ORF: 1449
• Locus ID: 152137
• Gene Summary: This gene encodes a soluble, cytoplasmic, tyrosine-phosphorylated protein with multiple ubiquitin-interacting domains. Mutations in this gene cause nonsyndromic, postlingual, progressive sensorineural DFNA44 hearing loss. In mouse, the protein is expressed in the inner ear during development and postnatal maturation and associates with microtubule-based structures. This protein may also function as a negative regulator of NF-kB signaling and as an effector of epidermal growth factor (EGF)-mediated cell signaling. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
  Transcript Variant: This variant (2) represents the longer transcript and encodes the long isoform. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The extent of this transcript is supported by transcript alignments.