Nav1.5 (SCN5A) (NM_198056) Human Untagged Clone

CAT#: SC307625

SCN5A (untagged)-Human sodium channel, voltage-gated, type V, alpha subunit (SCN5A), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SCN5A
• Synonyms: CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_198056 edited
  CCGAGACGGCGGCGGCGCCCGTAGGATGCAGGGATCGCTCCCCCGGGGCCGCTGAGCCTG
  CGCCCAGTGCCCCGAGCCCCGCGCCGAGCCGAGTCCGCGCCAAGCAGCAGCCGCCCACCC
  CGGGGCCCGGCCGGGGGACCAGCAGCTTCCCCACAGGCAACGTGAGGAGAGCCTGTGCCC
  AGAAGCAGGATGAGAAGATGGCAAACTTCCTATTACCTCGGGGCACCAGCAGCTTCCGCA
  GGTTCACACGGGAGTCCCTGGCAGCCATCGAGAAGCGCATGGCGGAGAAGCAAGCCCGCG
  GCTCAACCACCTTGCAGGAGAGCCGAGAGGGGCTG:CCCGAGGAGGAGGCTCCCCGG:CC
  CCAGCTGGACCTGCAGG:CCTCCAAAAAGCTGCCAGATCTCTATGGCAATCCACCCCAAG
  AGCTCATCGGAGAGCCCCTGGAGGACCTGGACCCCTTCTATAGCACCCAAAAGACTTTCA
  TCGTACTGAATAAAGGCAAGACCATCTTCCGGTTCAGTGCCACCAACGCCTTGTATGTCC
  TCAGTCCCTTCCACCCCATCCGGAGAGCGGCTGTGAAGATTCTGGTTCACTCGCTCTTCA
  ACATGCTCATCATGTGCACCATCCTCACCAACTGCGTGTTCATGGCCCAGCACGACCCTC
  CACCCTGGACCAAGTATGTCGAGTACACCTTCACCGCCATTTACACCTTTGAGTCTCTGG
  TCAAGATTCTGGCTCGAGGCTTCTGCCTGCACGCGTTCACTTTCCTTCGGGACCCATGGA
  ACTGGCTGGACTTTAGTGTGATTATCATGGCATACACAACTGAATTTGTGGACCTGGGCA
  ATGTCTCAGCCTTACGCACCTTCCGAGTCCTCCGGGCCCTGAAAACTATATCAGTCATTT
  CAGGGCTGAAGACCATCGTGGGGGCCCTGATCCAGTCTGTGAAGAAGCTGGCTGATGTGA
  TGGTCCTCACAGTCTTCTGCCTCAGCGTCTTTGCCCTCATCGGCCTGCAGCTCTTCATGG
  GCAACCTAAGGCACAAGTGCGTGCGCAACTTCACAGCGCTCAACGGCACCAACGGCTCCG
  TGGAGGCCGACGGCTTGGTCTGGGAATCCCTGGACCTTTACCTCAGTGATCCAGAAAATT
  ACCTGCTCAAGAACGGCACCTCTGATGTGTTACTGTGTGGGAACAGCTCTGACGCTGGGA
  CATGTCCGGAGGGCTACCGGTGCCTAAAGGCAGGCGAGAACCCCGACCACGGCTACACCA
  GCTTCGATTCCTTTGCCTGGGCCTTTCTTGCACTCTTCCGCCTGATGACGCAGGACTGCT
  GGGAGCGCCTCTATCAGCAGACCCTCAGGTCCGCAGGGAAGATCTACATGATCTTCTTCA
  TGCTTGTCATCTTCCTGGGGTCCTTCTACCTGGTGAACCTGATCCTGGCCGTGGTCGCAA
  TGGCCTATGAGGAGCAAAACCAAGCCACCATCGCTGAGACCGAGGAGAAGGAAAAGCGCT
  TCCAGGAGGCCATGGAAATGCTCAAGAAAGAACACGAGGCCCTCACCATCAGGGGTGTGG
  ATACCGTGTCCCGTAGCTCCTTGGAGATGTCCCCTTTGGCCCCAGTAAACAGCCATGAGA
  GAAGAAGCAAGAGGAGAAAACGGATGTCTTCAGGAACTGAGGAGTGTGGGGAGGACAGGC
  TCCCCAAGTCTGACTCAGAAGATGGTCCCAGAGCAATGAATCATCTCAGCCTCACCCGTG
  GCCTCAGCAGGACTTCTATGAAGCCACGTTCCAGCCGCGGGAGCATTTTCACCTTTCGCA
  GGCGAGACCTGGGTTCTGAAGCAGATTTTGCAGATGATGAAAACAGCACAGCGGGGGAGA
  GCGAGAGCCACCGCACATCACTGCTGGTGCCCTGGCCCCTGCGCCGGACCAGTGCCCAGG
  GACAGCCCAGTCCCGGAACCTCGGCTCCTGGCCACGCCCTCCATGGCAAAAAGAACAGCA
  CTGTGGACTGCAATGGGGTGGTCTCATTACTGGGGGCAGGCGACCCAGAGGCCACATCCC
  CAGGAAGCCACCTCCTCCGCCCTGTGATGCTAGAGCACCCGCCAGACACGACCACGCCAT
  CGGAGGAGCCAGGCGGGCCCCAGATGCTGACCTCCCAGGCTCCGTGTGTAGATGGCTTCG
  AGGAGCCAGGAGCACGGCAGCGGGCCCTCAGCGCAGTCAGCGTCCTCACCAGCGCACTGG
  AAGAGTTAGAGGAGTCTCGCCACAAGTGTCCACCATGCTGGAACCGTCTCGCCCAGCGCT
  ACCTGATCTGGGAGTGCTGCCCGCTGTGGATGTCCATCAAGCAGGGAGTGAAGTTGGTGG
  TCATGGACCCGTTTACTGACCTCACCATCACTATGTGCATCGTACTCAACACACTCTTCA
  TGGCGCTGGAGCACTACAACATGACAAGTGAATTCGAGGAGATGCTGCAGGTCGGAAACC
  TGGTCTTCACAGGGATTTTCACAGCAGAGATGACCTTCAAGATCATTGCCCTCGACCCCT
  ACTACTACTTCCAACAGGGCTGGAACATCTTCGACAGCATCATCGTCATCCTTAGCCTCA
  TGGAGCTGGGCCTGTCCCGCATGAGCAACTTGTCGGTGCTGCGCTCCTTCCGCCTGCTGC
  GGGTCTTCAAGCTGGCCAAATCATGGCCCACCCTGAACACACTCATCAAGATCATCGGGA
  ACTCAGTGGGGGCACTGGGGAACCTGACACTGGTGCTAGCCATCATCGTGTTCATCTTTG
  CTGTGGTGGGCATGCAGCTCTTTGGCAAGAACTACTCGGAGCTGAGGGACAGCGACTCAG
  GCCTGCTGCCTCGCTGGCACATGATGGACTTCTTTCATGCCTTCCTCATCATCTTCCGCA
  TCCTCTGTGGAGAGTGGATCGAGACCATGTGGGACTGCATGGAGGTGTCGGGGCAGTCAT
  TATGCCTGCTGGTCTTCTTGCTTGTTATGGTCATTGGCAACCTTGTGGTCCTGAATCTCT
  TCCTGGCCTTGCTGCTCAGCTCCTTCAGTGCAGACAACCTCACAGCCCCTGATGAGGACA
  GAGAGATGAACAACCTCCAGCTGGCCCTGGCCCGCATCCAGAGGGGCCTGCGCTTTGTCA
  AGCGGACCACCTGGGATTTCTGCTGTGGTCTCCTGCGGCAGCGGCCTCAGAAGCCCGCAG
  CCCTTGCCGCCCAGGGCCAGCTGCCCAGCTGCATTGCCACCCCCTACTCCCCGCCACCCC
  CAGAGACGGAGAAGGTGCCTCCCACCCGCAAGGAAACACGGTTTGAGGAAGGCGAGCAAC
  CAGGCCAGGGCACCCCCGGGGATCCAGAGCCCGTGTGTGTGCCCATCGCTGTGGCCGAGT
  CAGACACAGATGACCAAGAAGAGGATGAGGAGAACAGCCTGGGCACGGAGGAGGAGTCCA
  GCAAGCAGCAGGAATCCCAGCCTGTGTCCGGTGGCCCAGAGGCCCCTCCGGATTCCAGGA
  CCTGGAGCCAGGTGTCAGCGACTGCCTCCTCTGAGGCCGAGGCCAGTGCATCTCAGGCCG
  ACTGGCGGCAGCAGTGGAAAGCGGAACCCCAGGCCCCAGGGTGCGGTGAGACCCCAGAGG
  ACAGTTGCTCCGAGGGCAGCACAGCAGACATGACCAACACCGCTGAGCTCCTGGAGCAGA
  TCCCTGACCTCGGCCAGGATGTCAAGGACCCAGAGGACTGCTTCACTGAAGGCTGTGTCC
  GGCGCTGTCCCTGCTGTGCGGTGGACACCACACAGGCCCCAGGGAAGGTCTGGTGGCGGT
  TGCGCAAGACCTGCTACCACATCGTGGAGCACAGCTGGTTCGAGACATTCATCATCTTCA
  TGATCCTACTCAGCAGTGGAGCGCTGGCCTTCGAGGACATCTACCTAGAGGAGCGGAAGA
  CCATCAAGGTTCTGCTTGAGTATGCCGACAAGATGTTCACATATGTCTTCGTGCTGGAGA
  TGCTGCTCAAGTGGGTGGCCTACGGCTTCAAGAAGTACTTCACCAATGCCTGGTGCTGGC
  TCGACTTCCTCATCGTAGACGTCTCTCTGGTCAGCCTGGTGGCCAACACCCTGGGCTTTG
  CCGAGATGGGCCCCATCAAGTCACTGCGGACGCTGCGTGCACTCCGTCCTCTGAGAGCTC
  TGTCACGATTTGAGGGCATGAGGGTGGTGGTCAATGCCCTGGTGGGCGCCATCCCGTCCA
  TCATGAACGTCCTCCTCGTCTGCCTCATCTTCTGGCTCATCTTCAGCATCATGGGCGTGA
  ACCTCTTTGCGGGGAAGTTTGGGAGGTGCATCAACCAGACAGAGGGAGACTTGCCTTTGA
  ACTACACCATCGTGAACAACAAGAGCCAGTGTGAGTCCTTGAACTTGACCGGAGAATTGT
  ACTGGACCAAGGTGAAAGTCAACTTTGACAACGTGGGGGCCGGGTACCTGGCCCTTCTGC
  AGGTGGCAACATTTAAAGGCTGGATGGACATTATGTATGCAGCTGTGGACTCCAGGGGGT
  ATGAAGAGCAGCCTCAGTGGGAATACAACCTCTACATGTACATCTATTTTGTCATTTTCA
  TCATCTTTGGGTCTTTCTTCACCCTGAACCTCTTTATTGGTGTCATCATTGACAACTTCA
  ACCAACAGAAGAAAAAGTTAGGGGGCCAGGACATCTTCATGACAGAGGAGCAGAAGAAGT
  ACTACAATGCCATGAAGAAGCTGGGCTCCAAGAAGCCCCAGAAGCCCATCCCACGGCCCC
  TGAACAAGTACCAGGGCTTCATATTCGACATTGTGACCAAGCAGGCCTTTGACGTCACCA
  TCATGTTTCTGATCTGCTTGAATATGGTGACCATGATGGTGGAGACAGATGACCAAAGTC
  CTGAGAAAATCAACATCTTGGCCAAGATCAACCTGCTCTTTGTGGCCATCTTCACAGGCG
  AGTGTATTGTCAAGCTGGCTGCCCTGCGCCACTACTACTTCACCAACAGCTGGAATATCT
  TCGACTTCGTGGTTGTCATCCTCTCCATCGTGGGCACTGTGCTCTCGGACATCATCCAGA
  AGTACTTCTTCTCCCCGACGCTCTTCCGAGTCATCCGCCTGGCCCGAATAGGCCGCATCC
  TCAGACTGATCCGAGGGGCCAAGGGGATCCGCACGCTGCTCTTTGCCCTCATGATGTCCC
  TGCCTGCCCTCTTCAACATCGGGCTGCTGCTCTTCCTCGTCATGTTCATCTACTCCATCT
  TTGGCATGGCCAACTTCGCTTATGTCAAGTGGGAGGCTGGCATCGACGACATGTTCAACT
  TCCAGACCTTCGCCAACAGCATGCTGTGCCTCTTCCAGATCACCACGTCGGCCGGCTGGG
  ATGGCCTCCTCAGCCCCATCCTCAACACTGGGCCGCCCTACTGCGACCCCACTCTGCCCA
  ACAGCAATGGCTCTCGGGGGGACTGCGGGAGCCCAGCCGTGGGCATCCTCTTCTTCACCA
  CCTACATCATCATCTCCTTCCTCATCGTGGTCAACATGTACATTGCCATCATCCTGGAGA
  ACTTCAGCGTGGCCACGGAGGAGAGCACCGAGCCCCTGAGTGAGGACGACTTCGATATGT
  TCTATGAGATCTGGGAGAAATTTGACCCAGAGGCCACTCAGTTTATTGAGTATTCGGTCC
  TGTCTGACTTTGCCGATGCCCTGTCTGAGCCACTCCGTATCGCCAAGCCCAACCAGATAA
  GCCTCATCAACATGGACCTGCCCATGGTGAGTGGGGACCGCATCCATTGCATGGACATTC
  TCTTTGCCTTCACCAAAAGGGTCCTGGGGGAGTCTGGGGAGATGGACGCCCTGAAGATCC
  AGATGGAGGAGAAGTTCATGGCAGCCAACCCATCCAAGATCTCCTACGAGCCCATCACCA
  CCACACTCCGGCGCAAGCACGAAGAGGTGTCGGCCATGGTTATCCAGAGAGCCTTCCGCA
  GGCACCTGCTGCAACGCTCTTTGAAGCATGCCTCCTTCCTCTTCCGTCAGCAGGCGGGCA
  GCGGCCTCTCCGAAGAGGATGCCCCTGAGCGAGAGGGCCTCATCGCCTACGTGATGAGTG
  AGAACTTCTCCCGACCCCTTGGCCCACCCTCCAGCTCCTCCATCTCCTCCACTTCCTTCC
  CACCCTCCTATGACAGTGTCACTAGAGCCACCAGCGATAACCTCCAGGTGCGGGGGTCTG
  ACTACAGCCACAGTGAAGATCTCGCCGACTTCCCCCCTTCTCCGGACAGGGACCGTGAGT
  CCATCGTGTGAGCCTCGGCCTGGCTGGCCAGGACACACTGAAAAGCAGCCTTTTTCACCA
  TGGCAAACCTAAATGCAGTCAGTCACAAACCAGCCTGGGGCCTTCCTGGCTTTGGGAGTA
  AGAAATGGGCCTCAGCCCCGCGGATCAACCAGGCAGAGTTCTGTGGCGCCGCGTGGACAG
  CCGGAGCAGTTGGCCTGTGCTTGGAGGCCTCAGATAGACCTGTGACCTGGTCTGGTCAGG
  CAATGCCCTGCGGCTCTGGAAAGCAACTTCATCCCAGCTGCTGAGGCGAAATATAAAACT
  GAGACTGTATATGTTGTGAATGGGCTTTCATAAATTTATTATATTTGATATTTTTTTACT
  TGAGCAAAGAACTAAGGATTTTTCCATGGACATGGGCAGCAATTCACGCTGTCTCTTCTT
  AACCCTGAACAAGAGTGTCTATGGAGCAGCCGGAAGTCTGTTCTCAAAGCAGAAGTGGAA
  TCCAGTGTGGCTCCCACAGGTCTTCACTGCCCAGGGGTCGAATGGGGTCCCCCTCCCACT
  TGACCTGAGATGCTGGGAGGGCTGAACCCCCACTCACACAAGCACACACACACAGTCCTC
  ACACACGGAGGCCAGACACAGGCCGTGGGACCCAGGCTCCCAGCCTAAGGGAGACAGGCC
  TTTCCCTGCCGGCCCCCCAAGGATGGGGTTCTTGTCCACGGGGCTCACTCTGGCCCCCTA
  TTGTCTCCAAGGTCCCATTTTCCCCCTGTGTTTTCACGCAGGTCATATTGTCAGTCCTAC
  AAAAATAAAAGGCTTCCAGAGGAGAGTGGCCTGGGTCCCAGGGCTGGCCCTAGGCACTGA
  TAGTTGCCTTTTCTTCCCCTCCTGTAAGAGTATTAACAAAACCAAAGGACACAAGGGTGC
  AAGCCCCATTCACGGCCTGGCATGCAGCTTGTCCTTGCTCCTGGAACCTGGCAGGCCCTG
  CCCAGCCAGCCATCGGAAGAGAGGGCTGAGCCATGGGGGTTTGGGGCTAAGAAGTTCACC
  AGCCCTGAGCCATGGCGGCCCCTCAGCCTGCCTGAAGAGAGGAAACTGGCGATCTCCCAG
  GGCTCTCTGGACCATACGCGGAGGAGTTTTCTGTGTGGTCTCCAGCTCCTCTCCAGACAC
  AGAGACATGGGAGTGGGGAGCGGAGCTTGGCCCTGCGCCCTGTGCAGGGAAAGGGATGGT
  CAGGCCCAGTTCTCGTGCCCTTAGAGGGGAATGAACCATGGCACCTTTGAGAGAGGGGGC
  ACTGTGGTCAGGCCCAGCCTCTCTGGCTCAGCCCGGGATCCTGATGGCACCCACACAGAG
  GACCTCTTTGGGGCAAGATCCAGGTGGTCCCATAGGTCTTGTGAAAAGGCTTTTTCAGGG
  AAAAATATTTTACTAGTCCAATCACCCCCAGGACCTCTTCAGCTGCTGACAATCCTATTT
  AGCATATGCAAATCTTTTAACATAGAGAACTGTCACCCTGAGGTAACAGGGTCAACTGGC
  GAAGCCTGAGCAGGCAGGGGCTTGGCTGCCCCATTCCAGCTCTCCCATGGAGCCCCTCCA
  CCGGGCGCATGCCTCCCAGGCCACCTCAGTCTCACCTGCCGGCTCTGGGCTGGCTGCTCC
  TAACCTACCTCGCCGAGCTGTCGGAGGGCTGGACATTTGTGGCAGTGCTGAAGGGGGCAT
  TGCCGGCGAGTAAAGTATTATGTTTCTTCTTGTCACCCCAGTTCCCTTGGTGGCAACCCC
  AGACCCAACCCATGCCCCTGACAGATCTAGTTCTCTTCTCCTGTGTTCCCTTTGAGTCCA
  GTGTGGGACACGGTTTAACTGTCCCAGCGACATTTCTCCAAGTGGAAATCCTATTTTTGT
  AGATCTCCATGCTTTGCTCTCAAGGCTTGGAGAGGTATGTGCCCCTCCTGGGTGCTCACC
  GCCTGCTACACAGGCAGGAATGCGGTTGGGAGGCAGGTCGGGCTGCCAGCCCAGCTGGCC
  GGAAGGAGACTGTGGTTTTTGTGTGTGTGGACAGCCCGGGAGCTTTGAGACAGGTGCCTG
  GGGCTGGCTGCAGACGGTGTGGTTGGGGGTGGGAGGTGAGCTAGACCCAACCCTTAGCTT
  TTAGCCTGGCTGTCACCTTTTTAATTTCCAGAACTGCACAATGACCAGCAGGAGGGGAGA
  AGAGAGTAGGAAAAAGGAGGGAAGGACAGACATCAAGTGCCAGATGTTGTCTGAACTAAT
  CGAGCACTTCTCACCAAACTTCATGTATAAATAAAATACATATTTTTAAAACAAACCAAT
  AAATGGCTTACATGAAAAAAAAAAAAAAAAAAA
  
• Restriction Sites: Please inquire
• ACCN: NM_198056
• ORF Size: 6051 bp
• Insert Size: 8600
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to contain one SNP compared with NM_198056.1.

Reference Data

• RefSeq: NM_198056.1, NP_932173.1
• RefSeq Size: 8527
• RefSeq ORF: 6051
• Locus ID: 6331
• Protein Families: Druggable Genome, Ion Channels: Sodium, Transmembrane
• Gene Summary: The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) encodes the longest isoform (a).