ACSL5 (NM_203380) Human Untagged Clone

CAT#: SC308146

ACSL5 (untagged)-Human acyl-CoA synthetase long-chain family member 5 (ACSL5), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ACSL5
• Synonyms: ACS2; ACS5; FACL5
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_203380, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCTTTTTATCTTTAACTTTTTGTTTTCCCCACTTCCGACCCCGGCGTTGATCTGCATCCTGACATTTG
  GAGCTGCCATCTTCTTGTGGCTGATCACCAGACCTCAACCCGTCTTACCTCTTCTTGACCTGAACAATCA
  GTCTGTGGGAATTGAGGGAGGAGCACGGAAGGGGGTTTCCCAGAAGAACAATGACCTAACAAGTTGCTGC
  TTCTCAGATGCCAAGACTATGTATGAGGTTTTCCAAAGAGGACTCGCTGTGTCTGACAATGGGCCCTGCT
  TGGGATATAGAAAACCAAACCAGCCCTACAGATGGCTATCTTACAAACAGGTGTCTGATAGAGCAGAGTA
  CCTGGGTTCCTGTCTCTTGCATAAAGGTTATAAATCATCACCAGACCAGTTTGTCGGCATCTTTGCTCAG
  AATAGGCCAGAGTGGATCATCTCCGAATTGGCTTGTTACACGTACTCTATGGTAGCTGTACCTCTGTATG
  ACACCTTGGGACCAGAAGCCATCGTACATATTGTCAACAAGGCTGATATCGCCATGGTGATCTGTGACAC
  ACCCCAAAAGGCATTGGTGCTGATAGGGAATGTAGAGAAAGGCTTCACCCCGAGCCTGAAGGTGATCATC
  CTTATGGACCCCTTTGATGATGACCTGAAGCAAAGAGGGGAGAAGAGTGGAATTGAGATCTTATCCCTAT
  ATGATGCTGAGAACCTAGGCAAAGAGCACTTCAGAAAACCTGTGCCTCCTAGCCCAGAAGACCTGAGCGT
  CATCTGCTTCACCAGTGGGACCACAGGTGACCCCAAAGGAGCCATGATAACCCATCAAAATATTGTTTCA
  AATGCTGCTGCCTTTCTCAAATGTGTGGAGCATGCTTATGAGCCCACTCCTGATGATGTGGCCATATCCT
  ACCTCCCTCTGGCTCATATGTTTGAGAGGATTGTACAGGCTGTTGTGTACAGCTGTGGAGCCAGAGTTGG
  ATTCTTCCAAGGGGATATTCGGTTGCTGGCTGACGACATGAAGACTTTGAAGCCCACATTGTTTCCCGCG
  GTGCCTCGACTCCTTAACAGGATCTACGATAAGGTACAAAATGAGGCCAAGACACCCTTGAAGAAGTTCT
  TGTTGAAGCTGGCTGTTTCCAGTAAATTCAAAGAGCTTCAAAAGGGTATCATCAGGCATGATAGTTTCTG
  GGACAAGCTCATCTTTGCAAAGATCCAGGACAGCCTGGGCGGAAGGGTTCGTGTAATTGTCACTGGAGCT
  GCCCCCATGTCCACTTCAGTCATGACATTCTTCCGGGCAGCAATGGGATGTCAGGTGTATGAAGCTTATG
  GTCAAACAGAATGCACAGGTGGCTGTACATTTACATTACCTGGGGACTGGACATCAGGTCACGTTGGGGT
  GCCCCTGGCTTGCAATTACGTGAAGCTGGAAGATGTGGCTGACATGAACTACTTTACAGTGAATAATGAA
  GGAGAGGTCTGCATCAAGGGTACAAACGTGTTCAAAGGATACCTGAAGGACCCTGAGAAGACACAGGAAG
  CCCTGGACAGTGATGGCTGGCTTCACACAGGAGACATTGGTCGCTGGCTCCCGAATGGAACTCTGAAGAT
  CATCGACCGTAAAAAGAACATTTTCAAGCTGGCCCAAGGAGAATACATTGCACCAGAGAAGATAGAAAAT
  ATCTACAACAGGAGTCAACCAGTGTTACAAATTTTTGTACACGGGGAGAGCTTACGGTCATCCTTAGTAG
  GAGTGGTGGTTCCTGACACAGATGTACTTCCCTCATTTGCAGCCAAGCTTGGGGTGAAGGGCTCCTTTGA
  GGAACTGTGCCAAAACCAAGTTGTAAGGGAAGCCATTTTAGAAGACTTGCAGAAAATTGGGAAAGAAAGT
  GGCCTTAAAACTTTTGAACAGGTCAAAGCCATTTTTCTTCATCCAGAGCCATTTTCCATTGAAAATGGGC
  TCTTGACACCAACATTGAAAGCAAAGCGAGGAGAGCTTTCCAAATACTTTCGGACCCAAATTGACAGCCT
  GTATGAGCACATCCAGGATTAG
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_203380
• ORF Size: 2052 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_203380.1, NP_976314.1
• RefSeq Size: 3399
• RefSeq ORF: 2052
• Locus ID: 51703
• Protein Families: Transmembrane
• Protein Pathways: Adipocytokine signaling pathway, Fatty acid metabolism, Metabolic pathways, PPAR signaling pathway
• Gene Summary: The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in uterus and spleen, and in trace amounts in normal brain, but has markedly increased levels in malignant gliomas. This gene functions in mediating fatty acid-induced glioma cell growth. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (3) differs in the 5' UTR and coding region compared to variant 1. This results in translation initiation from a downstream ATG and an isoform (b) that has a shorter N-terminus compared to isoform a. Both variants 2 and 3 encode isoform b.