NALP1 (NLRP1) (NM_033004) Human Untagged Clone

CAT#: SC308738

NLRP1 (untagged)-Human NLR family, pyrin domain containing 1 (NLRP1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NLRP1
• Synonyms: AIADK; CARD7; CIDED; CLR17.1; DEFCAP; DEFCAP-L/S; MSPC; NAC; NALP1; PP1044; SLEV1; VAMAS1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_033004 edited
  GGTAAGAGCCAAGGCAAAGGACAGCACTGTTCTCTGCCTGCCTGATACCCTCACCACCTG
  GGAACATCCCCCAGACACCCTCTTAACTCCGGGACAGAGATGGCTGGCGGAGCCTGGGGC
  CGCCTGGCCTGTTACTTGGAGTTCCTGAAGAAGGAGGAGCTGAAGGAGTTCCAGCTTCTG
  CTCGCCAATAAAGCGCACTCCAGGAGCTCTTCGGGTGAGACACCCGCTCAGCCAGAGAAG
  ACGAGTGGCATGGAGGTGGCCTCGTACCTGGTGGCTCAGTATGGGGAGCAGCGGGCCTGG
  GACCTAGCCCTCCATACCTGGGAGCAGATGGGGCTGAGGTCACTGTGCGCCCAAGCCCAG
  GAAGGGGCAGGCCACTCTCCCTCATTCCCCTACAGCCCAAGTGAACCCCACCTGGGGTCT
  CCCAGCCAACCCACCTCCACCGCAGTGCTAATGCCCTGGATCCATGAATTGCCGGCGGGG
  TGCACCCAGGGCTCAGAGAGAAGGGTTTTGAGACAGCTGCCTGACACATCTGGACGCCGC
  TGGAGAGAAATCTCTGCCTCACTCCTCTACCAAGCTCTTCCAAGCTCCCCAGACCATGAG
  TCTCCAAGCCAGGAGTCACCCAACGCCCCCACATCCACAGCAGTGCTGGGGAGCTGGGGA
  TCCCCACCTCAGCCCAGCCTAGCACCCAGAGAGCAGGAGGCTCCTGGGACCCAATGGCCT
  CTGGATGAAACGTCAGGAATTTACTACACAGAAATCAGAGAAAGAGAGAGAGAGAAATCA
  GAGAAAGGCAGGCCCCCATGGGCAGCGGTGGTAGGAACGCCCCCACAGGCGCACACCAGC
  CTACAGCCCCACCACCACCCATGGGAGCCTTCTGTGAGAGAGAGCCTCTGTTCCACATGG
  CCCTGGAAAAATGAGGATTTTAACCAAAAATTCACACAGCTGCTACTTCTACAAAGACCT
  CACCCCAGAAGCCAAGATCCCCTGGTCAAGAGAAGCTGGCCTGATTATGTGGAGGAGAAT
  CGAGGACATTTAATTGAGATCAGAGACTTATTTGGCCCAGGCCTGGATACCCAAGAACCT
  CGCATAGTCATACTGCAGGGGGCTGCTGGAATTGGGAAGTCAACACTGGCCAGGCAGGTG
  AAGGAAGCCTGGGGGAGAGGCCAGCTGTATGGGGACCGCTTCCAGCATGTCTTCTACTTC
  AGCTGCAGAGAGCTGGCCCAGTCCAAGGTGGTGAGTCTCGCTGAGCTCATCGGAAAAGAT
  GGGACAGCCACTCCGGCTCCCATTAGACAGATCCTGTCTAGGCCAGAGCGGCTGCTCTTC
  ATCCTCGATGGTGTAGATGAGCCAGGATGGGTCTTGCAGGAGCCGAGTTCTGAGCTCTGT
  CTGCACTGGAGCCAGCCACAGCCGGCGGATGCACTGCTGGGCAGTTTGCTGGGGAAAACT
  ATACTTCCCGAGGCATCCTTCCTGATCACGGCTCGGACCACAGCTCTGCAGAACCTCATT
  CCTTCTTTGGAGCAGGCACGTTGGGTAGAGGTCCTGGGGTTCTCTGAGTCCAGCAGGAAG
  GAATATTTCTACAGATATTTCACAGATGAAAGGCAAGCAATTAGAGCCTTTAGGTTGGTC
  AAATCAAACAAAGAGCTCTGGGCCCTGTGTCTTGTGCCCTGGGTGTCCTGGCTGGCCTGC
  ACTTGCCTGATGCAGCAGATGAAGCGGAAGGAAAAACTCACACTGACTTCCAAGACCACC
  ACAACCCTCTGTCTACATTACCTTGCCCAGGCTCTCCAAGCTCAGCCATTGGGACCCCAG
  CTCAGAGACCTCTGCTCTCTGGCTGCTGAGGGCATCTGGCAAAAAAAGACCCTTTTCAGT
  CCAGATGACCTCAGGAAGCATGGGTTAGATGGGGCCATCATCTCCACCTTCTTGAAGATG
  GGTATTCTTCAAGAGCACCCCATCCCTCTGAGCTACAGCTTCATTCACCTCTGTTTCCAA
  GAGTTCTTTGCAGCAATGTCCTATGTCTTGGAGGATGAGAAGGGGAGAGGTAAACATTCT
  AATTGCATCATAGATTTGGAAAAGACGCTAGAAGCATATGGAATACATGGCCTGTTTGGG
  GCATCAACCACACGTTTCCTATTGGGCCTGTTAAGTGATGAGGGGGAGAGAGAGATGGAG
  AACATCTTTCACTGCCGGCTGTCTCAGGGGAGGAACCTGATGCAGTGGGTCCCGTCCCTG
  CAGCTGCTGCTGCAGCCACACTCTCTGGAGTCCCTCCACTGCTTGTACGAGACTCGGAAC
  AAAACGTTCCTGACACAAGTGATGGCCCATTTCGAAGAAATGGGCATGTGTGTAGAAACA
  GACATGGAGCTCTTAGTGTGCACTTTCTGCATTAAATTCAGCCGCCACGTGAAGAAGCTT
  CAGCTGATTGAGGGCAGGCAGCACAGATCAACATGGAGCCCCACCATGGTAGTCCTGTTC
  AGGTGGGTCCCAGTCACAGATGCCTATTGGCAGATTCTCTTCTCCGTCCTCAAGGTCACC
  AGAAACCTGAAGGAGCTGGACCTAAGTGGAAACTCGCTGAGCCACTCTGCAGTGAAGAGT
  CTTTGTAAGACCCTGAGACGCCCTCGCTGCCTCCTGGAGACCCTGCGGTTGGCTGGCTGT
  GGCCTCACAGCTGAGGACTGCAAGGACCTTGCCTTTGGGCTGAGAGCCAACCAGACCCTG
  ACCGAGCTGGACCTGAGCTTCAATGTGCTCACGGATGCTGGAGCCAAACACCTTTGCCAG
  AGACTGAGACAGCCGAGCTGCAAGCTACAGCGACTGCAGCTGGTCAGCTGTGGCCTCACG
  TCTGACTGCTGCCAGGACCTGGCCTCTGTGCTTAGTGCCAGCCCCAGCCTGAAGGAGCTA
  GACCTGCAGCAGAACAACCTGGATGACGTTGGCGTGCGACTGCTCTGTGAGGGGCTCAGG
  CATCCTGCCTGCAAACTCATACGCCTGGGGCTGGACCAGACAACTCTGAGTGATGAGATG
  AGGCAGGAACTGAGGGCCCTGGAGCAGGAGAAACCTCAGCTGCTCATCTTCAGCAGACGG
  AAACCAAGTGTGATGACCCCTACTGAGGGCCTGGATACGGGAGAGATGAGTAATAGCACA
  TCCTCACTCAAGCGGCAGAGACTCGGATCAGAGAGGGCGGCTTCCCATGTTGCTCAGGCT
  AATCTCAAACTCCTGGACGTGAGCAAGATCTTCCCAATTGCTGAGATTGCAGAGGAAAGC
  TCCCCAGAGGTAGTACCGGTGGAACTCTTGTGCGTGCCTTCTCCTGCCTCTCAAGGGGAC
  CTGCATACGAAGCCTTTGGGGACTGACGATGACTTCTGGGGCCCCACGGGGCCTGTGGCT
  ACTGAGGTAGTTGACAAAGAAAAGAACTTGTACCGAGTTCACTTCCCTGTAGCTGGCTCC
  TACCGCTGGCCCAACACGGGTCTCTGCTTTGTGATGAGAGAAGCGGTGACCGTTGAGATT
  GAATTCTGTGTGTGGGACCAGTTCCTGGGTGAGATCAACCCACAGCACAGCTGGATGGTG
  GCAGGGCCTCTGCTGGACATCAAGGCTGAGCCTGGAGCTGTGGAAGCTGTGCACCTCCCT
  CACTTTGTGGCTCTCCAAGGGGGCCATGTGGACACATCCCTGTTCCAAATGGCCCACTTT
  AAAGAGGAGGGGATGCTCCTGGAGAAGCCAGCCAGGGTGGAGCTGCATCACATAGTTCTG
  GAAAACCCCAGCTTCTCCCCCTTGGGAGTCCTCCTGAAAATGATCCATAATGCCCTGCGC
  TTCATTCCCGTCACCTCTGTGGTGTTGCTTTACCACCGCGTCCATCCTGAGGAAGTCACC
  TTCCACCTCTACCTGATCCCAAGTGACTGCTCCATTCGGAAGGCCATAGATGATCTAGAA
  ATGAAATTCCAGTTTGTGCGAATCCACAAGCCACCCCCGCTGACCCCACTTTATATGGGC
  TGTCGTTACACTGTGTCTGGGTCTGGTTCAGGGATGCTGGAAATACTCCCCAAGGAACTG
  GAGCTCTGCTATCGAAGCCCTGGAGAAGACCAGCTGTTCTCGGAGTTCTACGTTGGCCAC
  TTGGGATCAGGGATCAGGCTGCAAGTGAAAGACAAGAAAGATGAGACTCTGGTGTGGGAG
  GCCTTGGTGAAACCAGGAGATCTCATGCCTGCAACTACTCTGATCCCTCCAGCCCGCATA
  GCCGTACCTTCACCTCTGGATGCCCCGCAGTTGCTGCACTTTGTGGACCAGTATCGAGAG
  CAGCTGATAGCCCGAGTGACATCGGTGGAGGTTGTCTTGGACAAACTGCATGGACAGGTG
  CTGAGCCAGGAGCAGTACGAGAGGGTGCTGGCTGAGAACACGAGGCCCAGCCAGATGCGG
  AAGCTGTTCAGCTTGAGCCAGTCCTGGGACCGGAAGTGCAAAGATGGACTCTACCAAGCC
  CTGAAGGAGACCCATCCTCACCTCATTATGGAACTCTGGGAGAAGGGCAGCAAAAAGGGA
  CTCCTGCCACTCAGCAGCTGAAGTATCAACACCAGCCCTTGACCCTTGAGTCCTGGCTTT
  GGCTGACCCTTCTTTGGGTCTCAGTTTCTTTCTCTGCAAACAAGTTGCCATCTGGTTTGC
  C
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_033004 unedited
  NGAGTTCAAAATTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGCTGACTT
  CTTCCAGTGTCTTGCAGGCCCCTCTGGGCTCCTCCCTCCCCTGGCTTTTCCTACCACTCC
  CCCTCTATCGGCGTCTATCTGTAGGTGCCCTGGGATTTATAAAACTGGGTTCCGAATGCT
  GAATAAGAGACGGTAAGAGCCAAGGCAAAGGACAGCACTGTTCTCTGCCTGCCTGATACC
  CTCACCACCTGGGAACATCCCCCAGACACCCTCTTAACTCCGGGACAGAGATGGCTGGCG
  GAGCCTGGGGCCGCCTGGCCTGTTACTTGGAGTTCCTGAAGAAGGAGGAGCTGAAGGAGT
  TCCAGCTTCTGCTCGCCAATAAAGCGCACTCCAGGAGCTCTTCGGGTGAGACACCCGCTC
  AGCCAGAGAAGACGAGTGGCATGGAGGTGGCCTCGTACCTGGTGGCTCAGTATGGGGAGC
  AGCGGGCCTGGGACCTAGCCCTCCATACCTGGGAGCAGATGGGGCTGAGGTCACTGTGCG
  CCCAAGCCCAGGAAGGGGCAGGCCACTCTCCCTCATTCCCCTACAGCCCAAGTGAACCCC
  ACCTGGGGTCTCCCAGCCAACCCACCTCCACCGCAGTGCTAATGCCCTGGATCCATGAAT
  TGCCGGCGGGGTGCACCCAGGGCTCAGAGAGAAGGGTTTTGAGACAGCTGCCTGACACAT
  CTGGACGCCGCTGGAGAGAAATCTCTGCCTCACTCCTCTACCAAGCTCTTCCAAGCTCCC
  CAGACCATGAGTCTCCAAGCCAGGAGTCACCCAACGCCCCCACATCCACAGCAGTGCTGG
  GGAGCTGGGGATCCCCACCTCAGCCCAGCCTAGCACCCAGAGAGCAG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_033004 unedited
  TTTTTCCCCGTGCTCACGCAGGAGAGCACTGGGGAGGGGTCACAGGGATGCCACCCGGGA
  TCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTT
  TTTTTTTTCTAAAAGAGCTGTGATACTCCTTTATTTTCTGAATAAACTTCCTTCCACTTT
  ACTCTGTTGGCTTGCTCTTGTAGATCTTCCTGTACAAAGCCAAGAATCCACGTGGCCTCC
  CACGCTGAACCCCAATTTTGGGGCTCACCCTGTGACACAGCCAGAGGCAAATGGTTCCAT
  GTCCCTCCTATTCCTCTTTGCGCCTGGATGGGATCCGGAGGGCTCTAGGCTTGGCTGCTG
  TGGCCACCAAATGAGGCTCTATGAGGTCTGCAGGGGTCTTGCCAGCTCCAGATGGACATT
  CCCTGAGATGCTGTTAGGCCACCTGGACTGGGGCCCCCTGTGGCATCCCTGGCATGGACA
  CATAATGCCCAGCAAAGGCATCATCAAAGTTCCATTACTTTAGTGCTGGAAGGCAAACCA
  AATGGCAACTTGTTTGCAGAGAAAGAAACTGAGACCCAAAGAAGGGTCAGCCAAAGCCAG
  GACTCAAGGGTCAAGGGCTGGTGTTGATACTTCAGCTGCTGAGTGGCAGGAGTCCCTTTT
  TGCTGCCCTTCTCCCAGAGTTCCATAATGAGGTGAGGATGGGTCTCCTTCAGGGCTTGGT
  AGAGTCCATCTTTGCACTTCCGGTCCCAGGACTGGCTCAAGCTGAACAGCTTCCGCATCT
  GGCTGGGCCTCGTGTTCTCAGCCAGCACCCTCTCGTACTGCTCCTGGCTCAGCACCTGTC
  CATGCAGTTTGTCCAAAACAACCTCCACCGATGTCACTCGGGCTATCAGCTGCTCTCGAT
  ACTGGTCCACAAAGTGCAGCAACTGCGGGGCATCCAAAGGTTGAAGTACGGCTATGCGGG
  GCTGGAGGGATCAAATTAATTGCAGGCATGAAATCTCCTGGGTTTACCCAGGCCTCCCCA
  CCCAAAATCTCATCTTTCTTGTCTTTCATTTCAGCCCGAATCCTGATTCCAATGGGCCAA
  CTTAAAATCCCCAAAAAGCCTGGCTTTCCCAGGGCTTCAATACAAAAACCCCTTTCCTGG
  GGAAATATTCCCCTTCCCGAAACAAAACCAAAACATGTAAGAACCCCCAAAAAAATGGGG
  TACCGGGGGTGGCTTGGAATCCCCAAACGGAATTTTTTTTAAATTTTTTGGGCTTCAAGG
  AAACCT
  
• Restriction Sites: Please inquire
• ACCN: NM_033004
• ORF Size: 4422 bp
• Insert Size: 4600
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.

Reference Data

• RefSeq: NM_033004.2, NP_127497.1
• RefSeq Size: 5617
• RefSeq ORF: 4422
• Locus ID: 22861
• Protein Families: Druggable Genome
• Protein Pathways: NOD-like receptor signaling pathway
• Gene Summary: This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) encodes the longest isoform (1).