p114RhoGEF (ARHGEF18) (NM_015318) Human Untagged Clone

CAT#: SC308747

ARHGEF18 (untagged)-Human Rho/Rac guanine nucleotide exchange factor (GEF) 18 (ARHGEF18), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ARHGEF18
• Synonyms: P114-RhoGEF; p114RhoGEF; RP78; SA-RhoGEF
• Vector: PCMV6-Neo
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_015318 edited
  ATGACGGTCTCTCAGAAAGGGGGTCCCCAGCCAACACCGAGCCCGGCTGGCCCTGGGACG
  CAACTCGGACCAATCACAGGAGAGATGGATGAAGCCGATTCTGCGTTTTTAAAATTTAAG
  CAGACAGCTGATGACTCTCTGTCCCTTACATCTCCAAACACCGAGTCCATTTTTGTAGAA
  GATCCCTACACCGCCTCGCTGAGGAGTGAGATTGAGTCAGACGGCCACGAGTTTGAAGCT
  GAGTCCTGGAGCCTCGCCGTGGATGCAGCCTACGCCAAGAAGCAAAAGAGGGAGGTGGTG
  AAAAGACAAGATGTCCTTTATGAGCTGATGCAGACAGAGGTGCACCACGTGCGGACGCTC
  AAGATCATGCTGAAGGTGTACTCCAGGGCCCTGCAGGAGGAGCTGCAGTTCAGCAGCAAG
  GCCATTGGCCGCCTCTTCCCATGCGCTGACGACCTGCTGGAGACGCACAGCCACTTCCTC
  GCTCGGCTCAAGGAGCGCCGCCAGGAGTCCCTGGAGGAGGGCAGTGACCGGAATTATGTC
  ATCCAGAAAATCGGCGACCTCCTGGTTCAGCAGTTTTCAGGTGAAAATGGGGAGAGAATG
  AAAGAAAAGTACGGTGTGTTTTGTAGTGGCCACAATGAAGCTGTTAGTCATTACAAGTTG
  CTGCTTCAGCAAAACAAGAAATTTCAAAACTTGATCAAGAAAATTGGCAACTTCTCCATC
  GTGCGGCGGCTTGGCGTGCAGGAGTGCATTCTCCTGGTTACACAACGCATAACCAAATAC
  CCAGTGCTGGTGGAGCGCATCATCCAGAACACGGAAGCTGGCACTGAGGACTATGAAGAC
  CTGACCCAGGCCTTGAACCTCATCAAAGATATCATCTCACAAGTGGACGCCAAGGTCAGT
  GAGTGTGAGAAGGGCCAGCGCCTCAGGGAGATCGCAGGGAAGATGGACCTGAAGTCTTCC
  AGCAAACTCAAGAACGGGCTCACCTTCCGCAAGGAAGACATGCTTCAGCGGCAGCTCCAC
  CTGGAGGGCATGCTATGCTGGAAGACCACATCAGGGCGCTTGAAAGATATCCTGGCTATC
  CTGCTGACCGACGTACTTTTGCTGCTACAAGAAAAAGATCAGAAATACGTCTTTGCTTCT
  GTGGACTCAAAGCCACCCGTCATCTCGTTACAAAAGCTCATCGTGAGGGAAGTGGCCAAC
  GAGGAGAAAGCGATGTTTCTGATCAGCGCCTCCTTGCAAGGGCCGGAGATGTATGAAATC
  TACACGAGCTCCAAAGAGGACAGGAACGCCTGGATGGCCCACATCCAAAGGGCTGTGGAG
  AGCTGCCCTGACGAGGAGGAGGGGCCCTTCAGCCTGCCCGAAGAGGAAAGGAAGGTGGTC
  GAGGCCCGCGCCACGAGACTCCGGGACTTTCAAGAGCGGTTGAGCATGAAAGACCAGCTG
  ATCGCACAGAGCCTCCTAGAGAAACAGCAGATCTACCTGGAGATGGCCGAGATGGGCGGC
  CTCGAAGACCTGCCCCAGCCCCGAGGCCTATTCCGTGGAGGGGACCCATCCGAGACCCTG
  CAGGGGGAGCTAATTCTCAAGTCGGCCATGAGCGAGATCGAGGGCATCCAGAGCCTGATC
  TGCAGGCAGCTGGGCAGCGCCAACGGCCAGGCGGAAGACGGAGGCAGCTCCACAGGCCCG
  CCCAGGAGGGCTGAGACCTTCGCGGGCTACGACTGCACAAACAGCCCCACCAAGAATGGC
  AGTTTCAAGAAGAAAGTCAGCAGCACTGACCCCAGGCCCCGAGACTGGCGAGGCCCCCCA
  AACAGCCCGGACTTGAAGCTCAGTGACAGTGACATTCCTGGGAGCTCTGAGGAATCGCCG
  CAGGTGGTGGAGGCGCCAGGCACGGAATCCGATCCCCGTCTGCCCACCGTCCTGGAGTCG
  GAGCTTGTCCAGCGGATCCAGACACTGTCCCAGCTGCTCCTGAACCTTCAGGCGGTAATC
  GCCCACCAGGACAGCTATGTGGAGACGCAGCGGGCTGCCATCCAGGAGCGGGAGAAGCAG
  TTCCGGCTGCAGTCGACGCGTGGGAACCTGCTGCTGGAGCAGGAGCGGCAACGCAACTTC
  GAGAAGCAGCGGGAGGAGCGCGCGGCCCTGGAGAAGCTGCAGAGCCAGCTGCGGCACGAG
  CAGCAGCGCTGGGAGCGCGAGCGCCAGTGGCAGCACCAGGAGCTGGAGCGTGCGGGCGCG
  CGGCTGCAGGAGCGCGAGGGCGAGGCGCGGCAGCTACGCGAGCGGCTGGAGCAGGAGCGG
  GCCGAGCTGGAGCGCCAGCGCCAGGCCTACCAGCACGACCTGGAGCGGCTGCGCGAGGCC
  CAGCGTGCCGTGGAGCGCGAGCGGGAGCGCCTGGAGCTGCTGCGCCGCCTCAAGAAGCAG
  AACACCGCGCCAGGCGCGCTGCCGCCCGACACACTGGCCGAGGCCCAGCCCCCAAGCCAC
  CCTCCCAGCTTCAACGGGGAAGGGCTGGAGGGCCCTCGTGTGAGCATGCTGCCATCCGGC
  GTGGGGCCAGAGTACGCAGAGCGCCCCGAGGTGGCTCGCCGGGACAGCGCCCCCACCGAG
  AACCGGCTGGCCAAGAGCGATGTGCCCATCCAGCTGCTCAGCGCCACCAACCAGTTCCAG
  AGGCAGGCGGCCGTGCAGCAGCAGATCCCCACCAAGCTGGCGGCCTCCACCAAGGGTGGC
  AAGGACAAGGGCGGCAAGAGCAGGGGCTCTCAGCGCTGGGAGAGCTCAGCGTCCTTCGAC
  CTGAAGCAGCAGCTGCTGCTCAACAAGCTCATGGGGAAAGATGAGAGCACCTCACGGAAC
  CGCCGCTCGCTGAGCCCTATCCTGCCCGGCAGACACAGTCCTGCGCCCCCACCAGACCCT
  GGCTTCCCCGCCCCGAGCCCACCGCCAGCTGACAGCCCCTCCGAGGGCTTCTCTCTCAAG
  GCCGGGGGCACAGCCCTCCTGCCCGGGCCCCCAGCTCCCTCGCCACTGCCGGCCACACCA
  CTCAGCGCCAAGGAGGACGCCAGCAAAGAAGACGTCATCTTCTTCTAA
  
• Restriction Sites: Please inquire
• ACCN: NM_015318
• ORF Size: 3048 bp
• Insert Size: 3000
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_015318.2, NP_056133.2
• RefSeq Size: 5386
• RefSeq ORF: 3048
• Locus ID: 23370
• Domains: RhoGEF, PH
• Gene Summary: Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GEF family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Nov 2018]
  Transcript Variant: This variant (1) represents the shorter transcript, and encodes the shorter isoform (a).