NHLRC1 (NM_198586) Human Untagged Clone

CAT#: SC309388

NHLRC1 (untagged)-Human NHL repeat containing 1 (NHLRC1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NHLRC1
• Synonyms: bA204B7.2; EPM2A; EPM2B; MALIN
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_198586, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCGGCCGAAGCCTCGGAGAGCGGGCCAGCGCTGCATGAGCTCATGCGCGAGGCGGAGATCAGCCTGC
  TCGAGTGCAAGGTGTGCTTTGAGAAGTTTGGCCACCGGCAGCAGCGGCGCCCGCGCAACCTGTCCTGCGG
  CCACGTGGTCTGCCTGGCCTGCGTGGCCGCCCTGGCGCACCCGCGCACTCTGGCCCTCGAGTGCCCATTC
  TGCAGGCGAGCTTGCCGGGGCTGCGACACCAGCGACTGCCTGCCGGTGCTGCACCTCATAGAGCTCCTGG
  GCTCAGCGCTTCGCCAGTCCCCGGCCGCCCATCGCGCCGCCCCCAGCGCCCCCGGAGCCCTCACCTGCCA
  CCACACCTTCGGCGGCTGGGGGACCCTGGTCAACCCCACCGGACTGGCGCTTTGTCCCAAGACGGGGCGT
  GTCGTGGTGGTGCACGACGGCAGGAGGCGTGTCAAGATTTTTGACTCAGGGGGAGGATGCGCGCATCAGT
  TTGGAGAGAAGGGGGACGCTGCCCAAGACATTAGGTACCCTGTGGATGTCACCATCACCAACGACTGCCA
  TGTGGTTGTCACTGACGCCGGCGATCGCTCCATCAAAGTGTTTGATTTTTTTGGCCAGATCAAGCTTGTC
  ATTGGAGGCCAATTCTCCTTACCTTGGGGTGTGGAGACCACCCCTCAGAATGGGATTGTGGTAACTGATG
  CGGAGGCAGGGTCCCTGCACCTCCTGGACGTCGACTTCGCGGAAGGGGTCCTTCGGAGAACTGAAAGGTT
  GCAAGCTCATCTGTGCAATCCCCGAGGGGTGGCAGTGTCTTGGCTCACCGGGGCCATTGCGGTCCTGGAG
  CACCCCCTGGCCCTGGGGACTGGGGTTTGCAGCACCAGGGTGAAAGTGTTTAGCTCAAGTATGCAGCTTG
  TCGGCCAAGTGGATACCTTTGGGCTGAGCCTCTACTTTCCCTCCAAAATAACTGCCTCCGCTGTGACCTT
  TGATCACCAGGGAAATGTGATTGTTGCAGATACATCTGGTCCAGCTATCCTTTGCTTAGGAAAACCTGAG
  GAGTTTCCAGTACCGAAGCCCATGGTCACTCATGGTCTTTCGCATCCTGTGGCTCTTACCTTCACCAAGG
  AGAATTCTCTTCTTGTGCTGGACACAGCATCTCATTCTATAAAAGTCTATAAAGTTGACTGGGGGTGA
  
  
• Restriction Sites: AscI-MluI
• ACCN: NM_198586
• ORF Size: 1188 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_198586.2, NP_940988.2
• RefSeq Size: 2134
• RefSeq ORF: 1188
• Locus ID: 378884
• Protein Pathways: Ubiquitin mediated proteolysis
• Gene Summary: The protein encoded by this gene is a single subunit E3 ubiquitin ligase. Laforin is polyubiquitinated by the encoded protein. Defects in this intronless gene lead to an accumulation of laforin and onset of Lafora disease, also known as progressive myoclonic epilepsy type 2 (EPM2). [provided by RefSeq, Mar 2010]