KCNH4 (NM_012285) Human Untagged Clone

CAT#: SC310004

KCNH4 (untagged)-Human potassium voltage-gated channel, subfamily H (eag-related), member 4 (KCNH4)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KCNH4
• Synonyms: BEC2; ELK1; Kv12.3
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_012285 edited
  ATGCCGGTCATGAAGGGGTTGCTGGCCCCGCAAAACACCTTCCTGGACACCATCGCCACC
  CGTTTTGACGGAACGCACAGCAACTTCCTGCTGGCCAACGCACAGGGCACACGGGGCTTT
  CCCATCGTCTACTGCTCCGACGGCTTCTGCGAGCTCACAGGCTACGGTCGCACCGAGGTC
  ATGCAGAAGACCTGCAGCTGCCGTTTCCTCTACGGCCCAGAGACCAGTGAGCCAGCCCTG
  CAGCGTCTGCACAAAGCCCTGGAGGGCCACCAGGAGCACCGGGCTGAAATCTGCTTCTAC
  CGCAAGGATGGCTCAGCCTTTTGGTGCCTCCTGGACATGATGCCCATCAAGAATGAGATG
  GGGGAGGTCGTGCTGTTCCTCTTTTCCTTCAAGGATATCACTCAGAGTGGAAGCCCAGGA
  CTTGGCCCCCAAGGAGGCCGCGGGGACAGTAATCACGAAAACTCCCTTGGTAGAAGGGGA
  GCCACCTGGAAATTTCGGTCTGCCAGAAGACGGAGCCGTACTGTCCTACACCGACTGACC
  GGCCACTTTGGCCGCCGGGGCCAGGGAGGCATGAAGGCCAATAATAACGTGTTTGAGCCA
  AAGCCATCAGTGCCCGAGTACAAGGTGGCCTCCGTGGGGGGGTCTCGCTGCCTCCTCCTC
  CACTACAGCGTCTCCAAGGCCATCTGGGACGGCCTTATCCTCCTTGCCACCTTCTACGTT
  GCGGTCACCGTCCCCTACAATGTCTGTTTCTCGGGTGACGATGACACCCCCATCACTTCG
  CGACACACCCTTGTCAGCGACATCGCCGTGGAAATGCTCTTCATCCTAGATATCATCCTG
  AACTTCCGCACCACCTATGTGTCCCAGTCCGGCCAGGTAATCTCTGCTCCTCGTTCCATT
  GGCCTCCACTACCTGGCCACCTGGTTCTTCATCGACCTTATTGCTGCTCTGCCCTTTGAC
  CTGCTTTACATCTTCAACATCACCGTGACCTCGCTGGTGCACCTACTGAAGACAGTGCGG
  CTGTTGCGGCTGCTGCGGCTGCTGCAGAAGCTGGAGCGGTACTCTCAGTGCAGTGCTGTG
  GTGCTCACGCTGCTCATGTCGGTCTTTGCGCTCCTTGCCCACTGGATGGCCTGCATCTGG
  TATGTCATCGGGCGCCGGGAGATGGAGGCCAATGACCCGCTGCTCTGGGACATTGGCTGG
  TTGCATGAGTTGGGCAAGCGTCTGGAGGTGCCCTATGTCAATGGCTCGGTGGGCGGCCCA
  TCACGGCGCAGCGCCTACATCGCGGCACTGTACTTCACTCTAAGCAGCCTCACCAGTGTG
  GGCTTTGGCAACGTGTGTGCCAACACCGACGCGGAGA::::::AGATCTTCTCCATCTGC
  ACGATGCTCATAGGCGCCCTGATGCACGCTGTGGTGTTCGGGAACGTGACAGCCATCATC
  CAGCGCATGTACTCGCGCCGCTCGCTCTACCACAGCCGCATGAAGGACCTCAAGGACTTC
  ATCCGTGTGCACCGCCTGCCGCGGCCGCTCAAGCAGCGCATGCTCGAATACTTCCAGACC
  ACGTGGGCCGTCAACAGCGGCATCGACGCCAACGAGTTACTGCGTGACTTCCCAGACGAG
  CTGAGAGCTGACATTGCTATGCACCTGAATCGGGAGATCCTGCAGCTGCCGTTGTTCGGG
  GCAGCGAGCAGGGGCTGCCTGCGGGCCCTATCGCTGCACATCAAGACCTCGTTCTGCGCT
  CCGGGCGAGTACCTGTTGCGCCGTGGGGATGCCCTGCAGGCACATTACTATGTCTGCTCC
  GGCTCGCTTGAGGTGCTCCGAGACAACATGGTGCTGGCCATCCTGGGGAAGGGGGACCTG
  ATTGGAGCAGATATCCCTGAGCCGGGGCAGGAGCCTGGGTTGGGAGCAGACCCAAACTTC
  GTGCTAAAGACCAGTGCTGATGTGAAAGCTCTGACCTACTGTGGCCTGCAGCAGCTGAGC
  AGCCGAGGGCTGGCTGAGGTCCTGAGGCTCTATCCTGAGTATGGGGCTGCCTTCCGGGCT
  GGCCTGCCCCGGGACCTCACCTTCAACCTGCGCCAGGGCTCTGACACCAGTGGCCTCAGC
  CGCTTTTCCCGATCCCCTCGCCTCTCCCAGCCCCGCTCAGAAAGCCTCGGCTCCTCCTCA
  GACAAGACGCTGCCATCCATCACAGAGGCCGAGAGTGGCGCGGAGCCTGGGGGTGGTCCC
  AGGCCCCGACGGCCCCTCCTGCTGCCCAACCTCAGCCCAGCACGGCCTCGGGGCTCCCTG
  GTCAGCCTTTTGGGCGAGGAGCTGCCCCCATTCTCAGCCCTTGTCTCCTCTCCTTCCTTA
  TCCCCATCCCTGTCCCCTGCCCTGGCTGGCCAGGGCCACAGTGCCTCCCCTCACGGCCCC
  CCCAGGTGCTCTGCTGCCTGGAAGCCCCCTCAGCTTCTCATTCCCCCACTGGGAACCTTT
  GGACCTCCGGACCTCAGTCCCCGGATAGTGGATGGCATTGAGGACTCTGGCAGCACAGCT
  GAGGCCCCTTCATTCCGATTCAGCAGGAGGCCTGAACTGCCAAGGCCCCGCTCCCAGGCG
  CCCCCTACAGGGACCAGGCCCAGCCCAGAATTGGCCAGTGAGGCTGAGGAGGTGAAGGAA
  AAGGTTTGCCGGCTGAACCAGGAGATCTCTCGTCTCAATCAGGAGGTGTCTCAGCTTAGC
  CGGGAGCTGCGGCACATCATGGGCCTGCTGCAGGCCAGGCTGGGTCCCCCAGGCCACCCA
  GCAGGCTCCGCTTGGACCCCAGACCCTCCTTGTCCACAGCTGAGGCCACCATGCCTCTCT
  CCTTGTGCGTCCAGACCACCACCCAGCCTCCAGGATACTACGCTTGCTGAAGTTCACTGC
  CCAGCCAGTGTGGGGACCATGGAGACAGGGACTGCGCTCCTGGACTTGAGACCTTCCATA
  TTGCCCCCCTACCCCTCAGAGCCTGACCCTCTGGGACCCTCTCCAGTGCCAGAGGCCTCA
  CCCCCAACCCCAAGCCTCTTGAGGCACAGTTTCCAGTCCAGGTCAGACACGTTCCACTGA
  
• Restriction Sites: Please inquire
• ACCN: NM_012285
• ORF Size: 3054 bp
• Insert Size: 3200
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_012285.1, NP_036417.1
• RefSeq Size: 3920
• RefSeq ORF: 3054
• Locus ID: 23415
• Protein Families: Druggable Genome, Ion Channels: Potassium, Transmembrane
• Gene Summary: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. The gene is brain-specific, and located in the neocortex and the striatum. It may be involved in cellular excitability of restricted neurons in the central nervous system. [provided by RefSeq, Jul 2008]