ARTS1 (ERAP1) (NM_016442) Human Untagged Clone

CAT#: SC310034

ERAP1 (untagged)-Human endoplasmic reticulum aminopeptidase 1 (ERAP1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ERAP1
• Synonyms: A-LAP; ALAP; APPILS; ARTS-1; ARTS1; ERAAP; ERAAP1; PILS-AP; PILSAP
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_016442 edited
  CGGCGGCAGTGGTGGTGGCGGCGGCGCAAGGGTGAGGGCGGCCCCAGAACCCCAGGTAGG
  TAGAGCAAGAAGATGGTGTTTCTGCCCCTCAAATGGTCCCTTGCAACCATGTCATTTCTA
  CTTTCCTCACTGTTGGCTCTCTTAACTGTGTCCACTCCTTCATGGTGTCAGAGCACTGAA
  GCATCTCCAAAACGTAGTGATGGGACACCATTTCCTTGGAATAAAATACGACTTCCTGAG
  TACGTCATCCCAGTTCATTATGATCTCTTGATCCATGCAAACCTTACCACGCTGACCTTC
  TGGGGAACCACGAAAGTAGAAATCACAGCCAGTCAGCCCACCAGCACCATCATCCTGCAT
  AGTCACCACCTGCAGATATCTAGGGCCACCCTCAGGAAGGGAGCTGGAGAGAGGCTATCG
  GAAGAACCCCTGCAGGTCCTGGAACACCCCCGTCAGGAGCAAATTGCACTGCTGGCTCCC
  GAGCCCCTCCTTGTCGGGCTCCCGTACACAGTTGTCATTCACTATGCTGGCAATCTTTCG
  GAGACTTTCCACGGATTTTACAAAAGCACCTACAGAACCAAGGAAGGGGAACTGAGGATA
  CTAGCATCAACACAATTTGAACCCACTGCAGCTAGAATGGCCTTTCCCTGCTTTGATGAA
  CCTGCCTTCAAAGCAAGTTTCTCAATCAAAATTAGAAGAGAGCCAAGGCACCTAGCCATC
  TCCAATATGCCATTGGTGAAATCTGTGACTGTTGCTGAAGGACTCATAGAAGACCATTTT
  GATGTCACTGTGAAGATGAGCACCTATCTGGTGGCCTTCATCATTTCAGATTTTGAGTCT
  GTCAGCAAGATAACCAAGAGTGGAGTCAAGGTTTCTGTTTATGCTGTGCCAGACAAGATA
  AATCAAGCAGATTATGCACTGGATGCTGCGGTGACTCTTCTAGAATTTTATGAGGATTAT
  TTCAGCATACCGTATCCCCTACCCAAACAAGATCTTGCTGCTATTCCCGACTTTCAGTCT
  GGTGCTATGGAAAACTGGGGACTGACAACATATAGAGAATCTGCTCTGTTGTTTGATGCA
  GAAAAGTCTTCTGCATCAAGTAAGCTTGGCATCACAATGACTGTGGCCCATGAACTGGCT
  CACCAGTGGTTTGGGAACCTGGTCACTATGGAATGGTGGAATGATCTTTGGCTAAATGAA
  GGATTTGCCAAATTTATGGAGTTTGTGTCTGTCAGTGTGACCCATCCTGAACTGAAAGTT
  GGAGATTATTTCTTTGGCAAATGTTTTGACGCAATGGAGGTAGATGCTTTAAATTCCTCA
  CACCCTGTGTCTACACCTGTGGAAAATCCTGCTCAGATCCGGGAGATGTTTGATGATGTT
  TCTTATGATAAGGGAGCTTGTATTCTGAATATGCTAAGGGAGTATCTTAGTGCTGACGCA
  TTTAAAAGTGGTATTGTACAGTATCTCCAGAAGCATAGCTATAAAAATACAAAAAACGAG
  GACCTGTGGGATAGTATGGCAAGTATTTGCCCTACAGATGGTGTAAAAGGGATGGATGGC
  TTTTGCTCTAGAAGTCAACATTCATCTTCATCCTCACATTGGCATCAGGAAGGGGTGGAT
  GTGAAAACCATGATGAACACTTGGACACTGCAGAAGGGTTTTCCCCTAATAACCATCACA
  GTGAGGGGGAGGAATGTACACATGAAGCAAGAGCACTACATGAAGGGCTCTGACGGCGCC
  CCGGACACTGGGTACCTGTGGCATGTTCCATTGACATTCATCACCAGCAAATCCGACATG
  GTCCATCGATTTTTGCTAAAAACAAAAACAGATGTGCTCATCCTCCCAGAAGAGGTGGAA
  TGGATCAAATTTAATGTGGGCATGAATGGCTATTACATTGTGCATTACGAGGATGATGGA
  TGGGACTCTTTGACTGGCCTTTTAAAAGGAACACACACAGCAGTCAGCAGTAATGATCGG
  GCGAGTCTCATTAACAATGCATTTCAGCTCGTCAGCATTGGGAAGCTGTCCATTGAAAAG
  GCCTTGGATTTATCCCTGTACTTGAAACATGAAACTGAAATTATGCCCGTGTTTCAAGGT
  TTGAATGAGCTGATTCCTATGTATAAGTTAATGGAGAAAAGAGATATGAATGAAGTGGAA
  ACTCAATTCAAGGCCTTCCTCATCAGGCTGCTAAGGGACCTCATTGATAAGCAGACATGG
  ACAGACGAGGGCTCAGTCTCAGAGCGAATGCTGCGGAGTCAACTACTACTCCTCGCCTGT
  GTGCACAACTATCAGCCGTGCGTACAGAGGGCAGAAGGCTATTTCAGAAAGTGGAAGGAA
  TCCAATGGAAACTTGAGCCTGCCTGTCGACGTGACCTTGGCAGTGTTTGCTGTGGGGGCC
  CAGAGCACAGAAGGCTGGGATTTTCTTTATAGTAAATATCAGTTTTCTTTGTCCAGTACT
  GAGAAAAGCCAAATTGAATTTGCCCTCTGCAGAACCCAAAATAAGGAAAAGCTTCAATGG
  CTACTAGATGAAAGCTTTAAGGGAGATAAAATAAAAACTCAGGAGTTTCCACAAATTCTT
  ACACTCATTGGCAGGAACCCAGTAGGATACCCACTGGCCTGGCAATTTCTGAGGAAAAAC
  TGGAACAAACTTGTACAAAAGTTTGAACTTGGCTCATCTTCCATAGCCCACATGGTAATG
  GGTACAACAAATCAATTCTCCACAAGAACACGGCTTGAAGAGGTAAAAGGATTCTTCAGC
  TCTTTGAAAGAAAATGGTTCTCAGCTCCGTTGTGTCCAACAGACAATTGAAACCATTGAA
  GAAAACATCGGTTGGATGGATAAGAATTTTGATAAAATCAGAGTGTGGCTGCAAAGTGAA
  AAGCTTGAACATGATCCTGAAGCTGACGCAACAGGATGAAAATCCATCAGAATCTCAGAC
  TACAGCACTAAATATGCTTTGATGCTACATCAAACGGAATGGAAGCATAGCTGACTTCGC
  TAAAGTTACTTCATCTCCATCTAGCAAATGAGGCACTGTTCTCAACCAAAGGAGATGGGG
  ATCTGGTTTAGGGCAATCCCTTTATAATTTGATGTGCTGTGGTCTCCTTGGTAATGTATA
  ATTTGGTATTGCACAGGTGATTAGTCAAGGAAGTCTGGAAAAGCTTTGGTCCCACAGCCT
  TGCCTCACAGCATGTAAATAATTAAAACAATATTGATGCTGAGGTTCTTCTACTGCTAGT
  ATGAAAGTGACAAATTTTTACTGGTGTGAATTGGGAAGAAAACAATGCTATTCCATGACG
  TTTGTAAAATGTTTGTAAAAGCTCAAACATGACGATTCCATAAAATAAACTTGAGGTTAA
  ATAATGGGTAGTAAATTATAGAATGTATAAGAAAAAATATAAAGGAGAAAATCAATTATC
  AGGAAAGCTAAAGAACTTTTCAAATCTAGTAATTTGAATATAGACACAATGCACTTTATT
  GCACTTTCAATTCTTATAAAGCAACAATAATATTAAGGTCCTTGACTATGTGTACAATGT
  TTTCACATATATAGTTTCATTTAATCATTTCAAAGTTAATCTCTGCCATCTCGCTAAATC
  ATCAGTCTCGGCTCTTCTGAAATAGAAGGTGCCTGATCTTCCTAATAATTCTGCCTATTT
  TCATTTGCTTTAAACAGGCGCCCTATTTTCTTTCTAGTTGTGGCTGCGCAAAAACATTTA
  TCTCCCAAATAAGATGTGCTGCTTACCGAGGTATCACGGGGTGGGGCTCCAGCTTGGGTC
  GTTGAAGCTGGGGTTTGGGAAACCACTTCAGAGATGGCAGCAGCAAGTTTAGCATCTTCA
  AATTTCTTTTATTGAAAAAAATTTTATTAGTAACATGTTGTATATAAAATTATGAGCACA
  ATGCCATCACTTAACTATAACTCTTAAAGATAGCTTAATGACTGTTTATTCTCTTGACCA
  AATAGACTCATAATAACATATAATTTTAAAAGAAATTTAAATTCTTTCTTCTCTATTGTA
  TTATTTTATACAATTTGCTATTTCTATTTCCTTCTCATATTGATTATTCTAAATACTATG
  CAATAATATAACTTAGAGTTCCACGGTTTGTTTACACATTTCCTGTTGTACATTTAGGTT
  ATTCAAAGTTTTCAGCTCTTTTAAAATTGCTCTGAATAAGTTCTAGTGAGTGAGTTATGG
  TGCTGGCTATATTTTGCTAAACTGCCCTCTCAAATGTTGCTAGGAATTCATACTGCGAAA
  AGCAATGAATAAGCATGCCTGTTTTCCCATGGCCTTGCTTGCCAGAATTTGACTTTTATT
  ATGATAATCAGTGTAAAATGATATACTACTATTGCTTGTATATTGTGGTATACGGTGTCA
  GGTTTCAGGGTTTTTTTTCAACGTTAAATATTCTAGAAACTTTCTGAAATAATTTCTGTT
  TAAAAATATTGAATATTTGCTTCATTTCAAATACTCCCTTTTGACAAAAAAACTTAGGTA
  TAACTGTTGATGAAAAACCAGAAAAAAGTCCAGAACTCTTTGGTGACTCCAACTATGGAT
  AGCTTATTTTGAAAAAGGAGAATTGCAAATTTTACCAAAAGATGGAGAAAAGCACATTAA
  AAAGATACCAACATTCAGAAATTCATTTCAGCATGTTATTATTGGAAATTATTTAAACTA
  ATTTAGATAACTATAAGATACTTATTGTCCATTTATACCCTGTAAAGCCGTTTTAGAATG
  TAATATTTTAGGTAATCCAAAATGTACTAAATTAAATTCATTTTTAGTTATGAGAAATCT
  TTGCTTATATGACAAATGAAAAGAATAACAAGTTGTCAAATGAAAAGAATGACATTGAAA
  CATTTGTATTGTCTCTTCTTAAACTATCTTATTGACTTATTATTTAAGCCTTTTAATACT
  AAGTATGAAACAACCTATGGTCTGGAAATTTGTATCGCAAAGCTATATGTGCATATGTTA
  TTTAATTCATCTAATGCTACACAAAAGCATAAAATAATGATTTTTCACTCTCTTTAAAAA
  TACTAAATCATTTATGTCCATTTCTCAATTTTTTCATTGATCTATGCTTTGAGTTTGCTT
  TCTCAACATTATTGTATTTTCCACTTATTATTACTGTATAACATATGCTAGTGTTTAGTT
  GGATTAATCTTACCTAAAAGTACTGAAAAATGCTTTTTAGTACTTTTTCATATTTTATAC
  ATTTATTTTCCGAATGTATCATTGAATAATTTTATTGAGTTATAAAAGTATCTTATTGCT
  ATTTAATAAAAAATTAACACATAAAATGAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_016442 unedited
  CGGCACGAGCGGCGGCAGTGGTGGTGGCGGCGGCGCAAGGGTGAGGGCGGCCCCAGAACC
  CCAGGTAGGTAGAGCAAGAAGATGGTGTTTCTGCCCCTCAAATGGTCCCTTGCAACCATG
  TCATTTCTACTTTCCTCACTGTTGGCTCTCTTAACTGTGTCCACTCCTTCATGGTGTCAG
  AGCACTGAAGCATCTCCAAAACGTAGTGATGGGACACCATTTCCTTGGAATAAAATACGA
  CTTCCTGAGTACGTCATCCCAGTTCATTATGATCTCTTGATCCATGCAAACCTTACCACG
  CTGACCTTCTGGGGAACCACGAAAGTAGAAATCACAGCCAGTCAGCCCACCAGCACCATC
  ATCCTGCATAGTCACCACCTGCAGATATCTAGGGCCACCCTCAGGAAGGGAGCTGGAGAG
  AGGCTATCGGAAGAACCCCTGCAGGTCCTGGAACACCCCCGTCAGGAGCAAATTGCACTG
  CTGGCTCCCGAGCCCCTCCTTGTCGGGCTCCCGTACACAGTTGTCATTCACTATGCTGGC
  AATCTTTCGGAGACTTTCCACGGATTTTACAAAAGCACCTACAGAACCAAGGAAGGGGAA
  CTGAGGATACTAGCATCAACACAATNTGAACCCACTGCAGCTAGAATGGCCTTTTCCTGC
  TTTGATGAACCTGCCTTCAAAGCAAGTTTCTCAATCAAAATTAGAAGAGAGCCAAGGCAC
  CTAGCCATCTCCAATATGCCATTGGTGAAATCTGTGACTGTTGCTGAAGGACTCATANAA
  GACCATTTTGATGTCACTGTGA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_016442 unedited
  CTCTGGCCCGCGNNGCCGCATTCTAGNGATCGAGTTTTTTTTTTTTTTTTTTTTTTTTTT
  TACATTTAAGGGGTAAATTTTTTATTAAATAGCAATAAGATACTTTTATAACTCAATAAA
  ATTATTCAATGATACATTCGGAAAATAAATGTATAAAATATGAAAAAGTCCTAAAAAGCA
  TTTTTCAGTACTTTTAGGTAAGATTAATCCAACTAAACACTAGCATATGTTATACAGTAA
  TAATAAGGGGAAAATACAATAATGTTGAGAAAGCAAACTCAAAGCATAGATCAATGAAAA
  AATTGAGAAAGGGACATAAATGATTTAGTATTTTTAAAGAGAGTGAAAAATCATTATTTT
  ATGCTTTTGGGTAGCATTAGATGAATTAAATAACATATGCACATATAGCTTTGCGATACA
  AATTTCCAGACCATAGGTTGTTTCATACTTAGTATTAAAAGGCTTAAATAATAAGTCAAT
  AAGATAGTTCAAGAAGAGAAATACAAATGCTTCAATGCCATTCTTTTCATTTGACAACTC
  GGTATTCTTTTCCATTGGCCATAAAGCCAAAATTTCCTCATACCCAAAACGGAATCCATC
  CTATCGCTTTTGGGCTCACCTAAAATATTACTTTTAAAACACGGTCTCCCGGCCATACCC
  GGGCCACATCCACCTTCCCCGTTTTCTCACTCCACCCTACCAAGCTTCCCATCTCTACGT
  GTTCCAATTGTCTCCTCTGCCCGTTTCGTTCCCTTTTCCCATGTGCTATTTGTTTCCCCC
  TCGCTCACCATCACGCCTTGTCTCGCTCTCCCCACCGCATCGACCGCCTCATACGGTCTC
  CTCTACTTTCTCCTNTTACCCTTGTTCCCGCCCCATTTTTCTTCTTCACCCTCTTTTGTC
  CCCCCCCCCTTCCCGCCCGCTTCCCCCCCGCCCCTTTGTCCCCCGCGCCTTCGCCCTCTC
  CCGTCCCCCTTTCCCCCCGTCCCACTTCCATCCATCCCCCCCCGTCAT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_016442
• ORF Size: 2847 bp
• Insert Size: 5300
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.

Reference Data

• RefSeq: NM_016442.3, NP_057526.3
• RefSeq Size: 5584
• RefSeq ORF: 2847
• Locus ID: 51752
• Domains: Peptidase_M1
• Protein Families: Druggable Genome, Protease, Secreted Protein
• Gene Summary: The protein encoded by this gene is an aminopeptidase involved in trimming HLA class I-binding precursors so that they can be presented on MHC class I molecules. The encoded protein acts as a monomer or as a heterodimer with ERAP2. This protein may also be involved in blood pressure regulation by inactivation of angiotensin II. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Variants 1 and 4 encode the same isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.