ARTS1 (ERAP1) (NM_016442) Human Untagged Clone

CAT#: SC318407

ERAP1 (untagged)-Human endoplasmic reticulum aminopeptidase 1 (ERAP1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ERAP1
• Synonyms: A-LAP; ALAP; APPILS; ARTS-1; ARTS1; ERAAP; ERAAP1; PILS-AP; PILSAP
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_016442, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGTGTTTCTGCCCCTCAAATGGTCCCTTGCAACCATGTCATTTCTACTTTCCTCACTGTTGGCTCTCT
  TAACTGTGTCCACTCCTTCATGGTGTCAGAGCACTGAAGCATCTCCAAAACGTAGTGATGGGACACCATT
  TCCTTGGAATAAAATACGACTTCCTGAGTACGTCATCCCAGTTCATTATGATCTCTTGATCCATGCAAAC
  CTTACCACGCTGACCTTCTGGGGAACCACGAAAGTAGAAATCACAGCCAGTCAGCCCACCAGCACCATCA
  TCCTGCATAGTCACCACCTGCAGATATCTAGGGCCACCCTCAGGAAGGGAGCTGGAGAGAGGCTATCGGA
  AGAACCCCTGCAGGTCCTGGAACACCCCCGTCAGGAGCAAATTGCACTGCTGGCTCCCGAGCCCCTCCTT
  GTCGGGCTCCCGTACACAGTTGTCATTCACTATGCTGGCAATCTTTCGGAGACTTTCCACGGATTTTACA
  AAAGCACCTACAGAACCAAGGAAGGGGAACTGAGGATACTAGCATCAACACAATTTGAACCCACTGCAGC
  TAGAATGGCCTTTCCCTGCTTTGATGAACCTGCCTTCAAAGCAAGTTTCTCAATCAAAATTAGAAGAGAG
  CCAAGGCACCTAGCCATCTCCAATATGCCATTGGTGAAATCTGTGACTGTTGCTGAAGGACTCATAGAAG
  ACCATTTTGATGTCACTGTGAAGATGAGCACCTATCTGGTGGCCTTCATCATTTCAGATTTTGAGTCTGT
  CAGCAAGATAACCAAGAGTGGAGTCAAGGTTTCTGTTTATGCTGTGCCAGACAAGATAAATCAAGCAGAT
  TATGCACTGGATGCTGCGGTGACTCTTCTAGAATTTTATGAGGATTATTTCAGCATACCGTATCCCCTAC
  CCAAACAAGATCTTGCTGCTATTCCCGACTTTCAGTCTGGTGCTATGGAAAACTGGGGACTGACAACATA
  TAGAGAATCTGCTCTGTTGTTTGATGCAGAAAAGTCTTCTGCATCAAGTAAGCTTGGCATCACAATGACT
  GTGGCCCATGAACTGGCTCACCAGTGGTTTGGGAACCTGGTCACTATGGAATGGTGGAATGATCTTTGGC
  TAAATGAAGGATTTGCCAAATTTATGGAGTTTGTGTCTGTCAGTGTGACCCATCCTGAACTGAAAGTTGG
  AGATTATTTCTTTGGCAAATGTTTTGACGCAATGGAGGTAGATGCTTTAAATTCCTCACACCCTGTGTCT
  ACACCTGTGGAAAATCCTGCTCAGATCCGGGAGATGTTTGATGATGTTTCTTATGATAAGGGAGCTTGTA
  TTCTGAATATGCTAAGGGAGTATCTTAGTGCTGACGCATTTAAAAGTGGTATTGTACAGTATCTCCAGAA
  GCATAGCTATAAAAATACAAAAAACGAGGACCTGTGGGATAGTATGGCAAGTATTTGCCCTACAGATGGT
  GTAAAAGGGATGGATGGCTTTTGCTCTAGAAGTCAACATTCATCTTCATCCTCACATTGGCATCAGGAAG
  GGGTGGATGTGAAAACCATGATGAACACTTGGACACTGCAGAAGGGTTTTCCCCTAATAACCATCACAGT
  GAGGGGGAGGAATGTACACATGAAGCAAGAGCACTACATGAAGGGCTCTGACGGCGCCCCGGACACTGGG
  TACCTGTGGCATGTTCCATTGACATTCATCACCAGCAAATCCGACATGGTCCATCGATTTTTGCTAAAAA
  CAAAAACAGATGTGCTCATCCTCCCAGAAGAGGTGGAATGGATCAAATTTAATGTGGGCATGAATGGCTA
  TTACATTGTGCATTACGAGGATGATGGATGGGACTCTTTGACTGGCCTTTTAAAAGGAACACACACAGCA
  GTCAGCAGTAATGATCGGGCGAGTCTCATTAACAATGCATTTCAGCTCGTCAGCATTGGGAAGCTGTCCA
  TTGAAAAGGCCTTGGATTTATCCCTGTACTTGAAACATGAAACTGAAATTATGCCCGTGTTTCAAGGTTT
  GAATGAGCTGATTCCTATGTATAAGTTAATGGAGAAAAGAGATATGAATGAAGTGGAAACTCAATTCAAG
  GCCTTCCTCATCAGGCTGCTAAGGGACCTCATTGATAAGCAGACATGGACAGACGAGGGCTCAGTCTCAG
  AGCGAATGCTGCGGAGTCAACTACTACTCCTCGCCTGTGTGCACAACTATCAGCCGTGCGTACAGAGGGC
  AGAAGGCTATTTCAGAAAGTGGAAGGAATCCAATGGAAACTTGAGCCTGCCTGTCGACGTGACCTTGGCA
  GTGTTTGCTGTGGGGGCCCAGAGCACAGAAGGCTGGGATTTTCTTTATAGTAAATATCAGTTTTCTTTGT
  CCAGTACTGAGAAAAGCCAAATTGAATTTGCCCTCTGCAGAACCCAAAATAAGGAAAAGCTTCAATGGCT
  ACTAGATGAAAGCTTTAAGGGAGATAAAATAAAAACTCAGGAGTTTCCACAAATTCTTACACTCATTGGC
  AGGAACCCAGTAGGATACCCACTGGCCTGGCAATTTCTGAGGAAAAACTGGAACAAACTTGTACAAAAGT
  TTGAACTTGGCTCATCTTCCATAGCCCACATGGTAATGGGTACAACAAATCAATTCTCCACAAGAACACG
  GCTTGAAGAGGTAAAAGGATTCTTCAGCTCTTTGAAAGAAAATGGTTCTCAGCTCCGTTGTGTCCAACAG
  ACAATTGAAACCATTGAAGAAAACATCGGTTGGATGGATAAGAATTTTGATAAAATCAGAGTGTGGCTGC
  AAAGTGAAAAGCTTGAACATGATCCTGAAGCTGACGCAACAGGATGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_016442
• ORF Size: 2847 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_016442.3, NP_057526.3
• RefSeq Size: 5584
• RefSeq ORF: 2847
• Locus ID: 51752
• Domains: Peptidase_M1
• Protein Families: Druggable Genome, Protease, Secreted Protein
• Gene Summary: The protein encoded by this gene is an aminopeptidase involved in trimming HLA class I-binding precursors so that they can be presented on MHC class I molecules. The encoded protein acts as a monomer or as a heterodimer with ERAP2. This protein may also be involved in blood pressure regulation by inactivation of angiotensin II. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Variants 1 and 4 encode the same isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.