NADPH oxidase 4 (NOX4) (NM_016931) Human Untagged Clone

CAT#: SC310253

NOX4 (untagged)-Human NADPH oxidase 4 (NOX4), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NOX4
• Synonyms: KOX; KOX-1; RENOX
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_016931 edited
  CCGCTGCCCCGGCCGCCGCCCGCTCCTTCTCGGTCCGGCGGGCACAGAGCGCAGCGCGGC
  GGGGCCGGCG GCATGGCTGTGTCCTGGAGGAGCTGGCTCGCCAACGAAGGGGTTAAACA
  CCTCTGCCTGTTCATCTGGCT CTCCATGAATGTCCTGCTTTTCTGGAAAACCTTCTTGC
  TGTATAACCAAGGGCCAGAGTATCACTACCTC CACCAGATGTTGGGGCTAGGATTGTGT
  CTAAGCAGAGCCTCAGCATCTGTTCTTAACCTCAACTGCAGCC TTATCCTTTTACCCAT
  GTGCCGAACACTCTTGGCTTACCTCCGAGGATCACAGAAGGTTCCAAGCAGGAG AACCA
  GGAGATTGTTGGATAAAAGCAGAACATTCCATATTACCTGTGGTGTTACTATCTGTATTT
  TCTCA GGCGTGCATGTGGCTGCCCATCTGGTGAATGCCCTCAACTTCTCAGTGAATTAC
  AGTGAAGACTTTGTTG AACTGAATGCAGCAAGATACCGAGATGAGGATCCTAGAAAACT
  TCTCTTCACAACTGTTCCTGGCCTGAC AGGGGTCTGCATGGTGGTGGTGCTATTCCTCA
  TGATCACAGCCTCTACATATGCAATAAGAGTTTCTAAC TATGATATCTTCTGGTATACT
  CATAACCTCTTCTTTGTCTTCTACATGCTGCTGACGTTGCATGTTTCAG GAGGGCTGCT
  GAAGTATCAAACTAATTTAGATACCCACCCTCCCGGCTGCATCAGTCTTAACCGAACCAG
  CTCTCAGAATATTTCCTTACCAGAGTATTTCTCAGAACATTTTCATGAACCTTTCCCTG
  AAGGATTTTCA AAACCGGCAGAGTTTACCCAGCACAAATTTGTGAAGATTTGTATGGAA
  GAGCCCAGATTCCAAGCTAATT TTCCACAGACTTGGCTTTGGATTTCTGGACCTTTGTG
  CCTGTACTGTGCCGAAAGACTTTACAGGTATAT CCGGAGCAATAAGCCAGTCACCATCA
  TTTCGGTCATAAGTCATCCCTCAGATGTCATGGAAATCCGAATG GTCAAAGAAAATTTT
  AAAGCAAGACCTGGTCAGTATATTACTCTACATTGTCCCAGTGTATCTGCATTAG AAAA
  TCATCCATTTACCCTCACAATGTGTCCAACTGAAACCAAAGCAACATTTGGGGTTCATCT
  TAAAAT AGTAGGAGACTGGACAGAACGATTTCGAGATTTACTACTGCCTCCATCTAGTC
  AAGACTCCGAAATTCTG CCCTTCATTCAATCTAGAAATTATCCCAAGCTGTATATTGAT
  GGTCCTTTTGGAAGTCCATTTGAGGAAT CACTGAACTATGAGGTCAGCCTCTGCGTGGC
  TGGAGGCATTGGAGTAACTCCATTTGCATCAATACTCAA CACCCTGTTGGATGACTGGA
  AACCATACAAGCTTAGAAGACTATACTTTATTTGGGTATGCAGAGATATC CAGTCCTTC
  CGTTGGTTTGCAGATTTACTCTGTATGTTGCATAACAAGTTTTGGCAAGAGAACAGACCT
  G ACTATGTCAACATCCAGCTGTACCTCAGTCAAACAGATGGGATACAGAAGATAATTGG
  AGAAAAATATCA TGCACTGAATTCAAGACTGTTTATAGGACGTCCTCGGTGGAAACTTT
  TGTTTGATGAAATAGCAAAATAT AACAGAGGAAAAACAGTTGGTGTTTTCTGTTGTGGA
  CCCAATTCACTATCCAAGACTCTTCATAAACTGA GTAACCAGAACAACTCATATGGGAC
  AAGATTTGAATACAATAAAGAGTCTTTCAGCTGAAAACTTTTGCC ATGAAGCAGGACTC
  TAAAGAAGGAATGAGTGCAATTTCTAAGACTTTGAAACTCAGCGGAATCAATCAGC TGT
  GTTATGCCAAAGAATAGTAAGGTTTTCTTATTTATGATTATTTAAAATGGAAATGTGAGA
  ATGTGGC AAGATGACCGTCACATTACATGTTTAATCTGGAAACCAAAGAGACCCTGAAG
  AATATTTGATGTGATGAT TCACTTTTCAGTTCTCAAATTAAAAGAAAACTGTTAGATGC
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_016931 unedited
  NNGGGTTCAAATTTGTATACGACTCACTATAGGCGGCCGCGAATTCAATCTGGTACCGGT
  CCGGAATTCCCGGGATCCGCTGCCCCGGCCGCCGCCCGCTCCTTCTCGGTCCGGCGGGCA
  CAGAGCGCAGCGCGGCGGGGCCGGCGGCATGGCTGTGTCCTGGAGGAGCTGGCTCGCCAA
  CGAAGGGGTTAAACACCTCTGCCTGTTCATCTGGCTCTCCATGAATGTCCTGCTTTTCTG
  GAAAACCTTCTTGCTGTATAACCAAGGGCCAGAGTATCACTACCTCCACCAGATGTTGGG
  GCTAGGATTGTGTCTAAGCAGAGCCTCAGCATCTGTTCTTAACCTCAACTGCAGCCTTAT
  CCTTTTACCCATGTGCCGAACACTCTTGGCTTACCTCCGAGGATCACAGAAGGTTCCAAG
  CAGGAGAACCAGGAGATTGTTGGATAAAAGCAGAACATTCCATATTACCTGTGGTGTTAC
  TATCTGTATTTTCTCAGGCGTGCATGTGGCTGCCCATCTGGTGAATGCCCTCAACTTCTC
  AGTGAATTACAGTGAAGACTTTGTTGAACTGAATGCAGCAAGATACCGAGATGAGGATCC
  TAGAAAACTTCTCTTCACAACTGTTCCTGGCCTGACAGGGGTCTGCATGGTGGTGGTGCT
  ATTCCTCATGATCACAGCCTCTACATATGCAATAAGAGTTTCTAACTATGATATCTTCTG
  GTATACTCATAACCTCTTCTTTGTCTTCTACATGCTGCTGACGTTGCATGTTTCANGAGG
  GCTGCTGAAGTATCAAACTAATTTAGATACCCACCCTCCCGGCTGCATCAGTCTTAACCG
  AACCAGCTCTCAGATATTTCCTTACCAGAGTATTTCTCAGAACATTTTCATGAACCTT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_016931 unedited
  AAGAGCAATGGGGAGGGTCAAGGGNNTAGCACCGGGTATGTTCAGAAAAGCTATGACCGC
  GGCCGCCCTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGCATCTAACAGTTNN
  TTCTTTTTAATTTGAGAACTGAAAAGTGAATCATCACATCAAATATTCTTCAGGGTCTCT
  TTGGTTTCCAGATTAAACATGTAATGTGACGGTCATCTTGCCACATTCTCACATTTCCAT
  TTTAAATAATCATAAATAAGAAAACCTTACTATTCTTTGGCATAACACAGCTGATTGATT
  CCGCTGAGTTTCAAAGTCTTAGAAATTGCACTCATTCCTTCTTTAGAGTCCTGCTTCATG
  GCAAAAGTTTTCAGCTGAAAGACTCTTTATTGTATTCAAATCTTGTCCCATATGAGTTGT
  TCTGGTTACTCAGTTTATGAAGAGTCTGNATAGTGAATTTGGGTCCACAACAGAAACACC
  AACTGGTTTTCCTCTGTTATATTTTGCTATTTCATCAAACAAAAGTTTCCACCCAGAACC
  TCCATTAACAGTCTTTGAATTCGTGCCTGAATTTTTTTTTTCCATTATCTTTTTGTTTCC
  CATCTGTTTTAACTGAAGGTACCACTGGGTTTTTGAACTTAATCCGGGTTTTGTTTTCTT
  TGGCAAACTTTGTTTTTGCCAACATCAACGAGTTAAATCCGGCAACACCACCGGGAGGGC
  TTGGGTTTTTTCTTGCTTTCCCCCAAAAAAAGTTTAATCTTTTTCAAACTTGGTTGGGGG
  TTTCCAGTTCACCCCCACGGGGTTGTTGAGTTTTTTGTGGCCCAAAGGGGGTTTTTTCCC
  CAAGGGCCCTCCCCCCCCCCCAGAGGTTG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_016931
• ORF Size: 1737 bp
• Insert Size: 2100
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.

Reference Data

• RefSeq: NM_016931.2, NP_058627.1
• RefSeq Size: 2416
• RefSeq ORF: 1737
• Locus ID: 50507
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]
  Transcript Variant: This variant (1) encodes isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.