NADPH oxidase 4 (NOX4) (NM_016931) Human Untagged Clone

CAT#: SC322623

NOX4 (untagged)-Human NADPH oxidase 4 (NOX4), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NOX4
• Synonyms: KOX; KOX-1; RENOX
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for SC322623 CCGCTGCCCCGGCCGCCGCCCGCTCCTTCTCGGTCCGGCGGGCACAGAGCGCAGCGCGGC
  GGGGCCGGCGGCATGGCTGTGTCCTGGAGGAGCTGGCTCGCCAACGAAGGGGTTAAACAC
  CTCTGCCTGTTCATCTGGCTCTCCATGAATGTCCTGCTTTTCTGGAAAACCTTCTTGCTG
  TATAACCAAGGGCCAGAGTATCACTACCTCCACCAGATGTTGGGGCTAGGATTGTGTCTA
  AGCAGAGCCTCAGCATCTGTTCTTAACCTCAACTGCAGCCTTATCCTTTTACCCATGTGC
  CGAACACTCTTGGCTTACCTCCGAGGATCACAGAAGGTTCCAAGCAGGAGAACCAGGAGA
  TTGTTGGATAAAAGCAGAACATTCCATATTACCTGTGGTGTTACTATCTGTATTTTCTCA
  GGCGTGCATGTGGCTGCCCATCTGGTGAATGCCCTCAACTTCTCAGTGAATTACAGTGAA
  GACTTTGTTGAACTGAATGCAGCAAGATACCGAGATGAGGATCCTAGAAAACTTCTCTTC
  ACAACTGTTCCTGGCCTGACAGGGGTCTGCATGGTGGTGGTGCTATTCCTCATGATCACA
  GCCTCTACATATGCAATAAGAGTTTCTAACTATGATATCTTCTGGTATACTCATAACCTC
  TTCTTTGTCTTCTACATGCTGCTGACGTTGCATGTTTCAGGAGGGCTGCTGAAGTATCAA
  ACTAATTTAGATACCCACCCTCCCGGCTGCATCAGTCTTAACCGAACCAGCTCTCAGAAT
  ATTTCCTTACCAGAGTATTTCTCAGAACATTTTCATGAACCTTTCCCTGAAGGATTTTCA
  AAACCGGCAGAGTTTACCCAGCACAAATTTGTGAAGATTTGTATGGAAGAGCCCAGATTC
  CAAGCTAATTTTCCACAGACTTGGCTTTGGATTTCTGGACCTTTGTGCCTGTACTGTGCC
  GAAAGACTTTACAGGTATATCCGGAGCAATAAGCCAGTCACCATCATTTCGGTCATAAGT
  CATCCCTCAGATGTCATGGAAATCCGAATGGTCAAAGAAAATTTTAAAGCAAGACCTGGT
  CAGTATATTACTCTACATTGTCCCAGTGTATCTGCATTAGAAAATCATCCATTTACCCTC
  ACAATGTGTCCAACTGAAACCAAAGCAACATTTGGGGTTCATCTTAAAATAGTAGGAGAC
  TGGACAGAACGATTTCGAGATTTACTACTGCCTCCATCTAGTCAAGACTCCGAAATTCTG
  CCCTTCATTCAATCTAGAAATTATCCCAAGCTGTATATTGATGGTCCTTTTGGAAGTCCA
  TTTGAGGAATCACTGAACTATGAGGTCAGCCTCTGCGTGGCTGGAGGCATTGGAGTAACT
  CCATTTGCATCAATACTCAACACCCTGTTGGATGACTGGAAACCATACAAGCTTAGAAGA
  CTATACTTTATTTGGGTATGCAGAGATATCCAGTCCTTCCGTTGGTTTGCAGATTTACTC
  TGTATGTTGCATAACAAGTTTTGGCAAGAGAACAGACCTGACTATGTCAACATCCAGCTG
  TACCTCAGTCAAACAGATGGGATACAGAAGATAATTGGAGAAAAATATCATGCACTGAAT
  TCAAGACTGTTTATAGGACGTCCTCGGTGGAAACTTTTGTTTGATGAAATAGCAAAATAT
  AACAGAGGAAAAACAGTTGGTGTTTTCTGTTGTGGACCCAATTCACTATCCAAGACTCTT
  CATAAACTGAGTAACCAGAACAACTCATATGGGACAAGATTTGAATACAATAAAGAGTCT
  TTCAGCTGAAAACTTTTGCCATGAAGCAGGACTCTAAAGAAGGAATGAGTGCAATTTCTA
  AGACTTTGAAACTCAGCGGAATCAATCAGCTGTGTTATGCCAAAGAATAGTAAGGTTTTC
  TTATTTATGATTATTTAAAATGGAAATGTGAGAATGTGGCAAGATGACCGTCACATTACA
  TGTTTAATCTGGAAACCAAAGAGACCCTGAAGAATATTTGATGTGATGATTCACTTTTCA
  GTTCTCAAATTAAAAGAAAACTGTTAGATGCAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for SC322623 unedited
  GCCGTATTTTGGTGCATTGTATACGACTCCTATAGGGCGGCCGGCGATCGCGGCGCGCCG
  GTACCGGTCCGGCGGGCACAGAGCGCAGCGCGGCGGGGCCGGCGGCATGGCTGTGTCCTG
  GAGGAGCTGGCTCGCCAACGAAGGGGTTAAACACCTCTGCCTGTTCATCTGGCTCTCCAT
  GAATGTCCTGCTTTTCTGGAAAACCTTCTTGCTGTATAACCAAGGGCCAGAGTATCACTA
  CCTCCACCAGATGTTGGGGCTAGGATTGTGTCTAAGCAGAGCCTCAGCATCTGTTCTTAA
  CCTCAACTGCAGCCTTATCCTTTTACCCATGTGCCGAATTCTTTTGGCTTACCTCCGAGG
  ATCACAGAAGGTTCCAAGCAGGAGAACCAGGAGATTGTTGGATAAAAGCAGAACATTCCA
  TATTACCTGTGGTGTTACTATCTGTATTTTCTCAGGCGTGCATGTGGCTGCCCATCTGGT
  GAATGCCCTCAACTTCTCAGTGAATTACAGTGAAGACTTTGTTGAACTGAATGCAGCAAG
  ATACCGAGATGAGGATCCTAGAAAACTTCTCTTCACAACTGTTCCTGGCCTGACAGGGGT
  CTGCATGGTGGTGGTGCTATTCCTCATGATCACAGCCTCTACATATGCAATAAGAGTTTC
  TAACTATGATATCTTCTGGTATACTCATAACCTCTTCTTTGTCTTCTACATGCTGCTGAC
  GTTGCATGTTTCAGGAGGGCTGCTGAAGTATCAAACTAATTTAGATACCCCACCCCTCCC
  GGCTGCATCAGTCTTAACCCGAACCAGCTCTCAGATATTTCTTACCAGAGTATTTCTCAG
  AACATTTTCATGACTTCCCTGAGATTTCAAACGGCAGAGTTACCAGCACAATTTGTGAGA
  TTGTATGAGAGCCAGATCCAGCTAATTTCACAGACTTGGCCTTTGAATTTCTGACTTTTG
  TGGCCTGTGTACTGGGCACG
• Restriction Sites: Please inquire
• ACCN: NM_016931
• ORF Size: 1737 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_016931.2, NP_058627.1
• RefSeq Size: 2416
• RefSeq ORF: 1737
• Locus ID: 50507
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]
  Transcript Variant: This variant (1) encodes isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.