HEY1 (NM_001040708) Human Untagged Clone

CAT#: SC311179

HEY1 (untagged)-Human hairy/enhancer-of-split related with YRPW motif 1 (HEY1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: HEY1
• Synonyms: BHLHb31; CHF2; HERP2; HESR1; hHRT1; HRT-1; NERP2; OAF1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001040708 edited
  GAGGCAAAGCGTGAGCGGGATCAGTGTGTGCGGAACGCAAGCAGCCGAGAGCGGAGAGGC
  GCCGCTGTAGTTAACTCCTCCCTGCCCGCCGCGCCGACCCTCCCCAGGAACCCCCAGGGA
  GCCAGCATGAAGCGAGCTCACCCCGAGTACAGCTCCTCGGACAGCGAGCTGGACGAGACC
  ATCGAGGTGGAGAAGGAGAGTGCGGACGAGAATGGAAACTTGAGTTCGGCTCTAGGTTCC
  ATGTCCCCAACTACATCTTCCCAGATTTTGGCCAGAAAAAGACGGAGAGGAATAATTGAG
  AAGCGCCGACGAGACCGGATCAATAACAGTTTGTCTGAGCTGAGAAGGCTGGTACCCAGT
  GCTTTTGAGAAGCAGGTAATGGAGCAAGGATCTGCTAAGCTAGAAAAAGCCGAGATCCTG
  CAGATGACCGTGGATCACCTGAAAATGCTGCATACGGCAGGAGGGAAAGGTTACTTTGAC
  GCGCACGCCCTTGCTATGGACTATCGGAGTTTGGGATTTCGGGAATGCCTGGCAGAAGTT
  GCGCGTTATCTGAGCATCATTGAAGGACTAGATGCCTCTGACCCGCTTCGAGTTCGACTG
  GTTTCGCATCTCAACAACTACGCTTCCCAGCGGGAAGCCGCGAGCGGCGCCCACGCGGGC
  CTCGGACACATTCCCTGGGGGACCGTCTTCGGACATCACCCGCACATCGCGCACCCGCTG
  TTGCTGCCCCAGAACGGCCACGGGAACGCGGGCACCACGGCCTCACCCACGGAACCGCAC
  CACCAGGGCAGGCTGGGCTCGGCACATCCGGAGGCGCCTGCTTTGCGAGCGCCCCCTAGC
  GGCAGCCTCGGACCGGTGCTCCCTGTGGTCACCTCCGCCTCCAAACTGTCGCCGCCTCTG
  CTCTCCTCAGTGGCCTCCCTGTCGGCCTTCCCCTTCTCTTTCGGCTCCTTCCACTTACTG
  TCTCCCAATGCACTGAGCCCTTCAGCACCCACGCAGGCTGCAAACCTTGGCAAGCCCTAT
  AGACCTTGGGGGACGGAGATCGGAGCTTTTTAAAGAACTGATGTAGAATGAGGGAGGGGA
  AAGTTTAAAATCCCAGCTGGGCTGGACTGTTGCCAACATCACCTTAAAGTCGTCAGTAAA
  AGTAAAAAGGAAAAAGGTACACTTTCAGATAATTTTTTTTTTAAAGACTAAAGGTTTGTT
  GGTTTACTTTTATCTTTTTTAATGTTTTTTTCATCATGTCATGTATTAGCAGTTTTTAAA
  AACTAGTTGTTAAATTTTGTTCAAGACATTAAATTGAAATAGTGAGTATAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001040708 unedited
  CTACACATTTGTACACGACTTACTACTAGGGCGGCCGCGAACTCGGCACGAGGCAAAGCG
  TGAGCGGGATCAGTGTGTGCGGAACGCAAGCAGCCGAGAGCGGAGAGGCGCCGCTGTAGT
  TAACTCCTCCCTGCCCGCCGCGCCGACCCTCCCCAGGAACCCCCAGGGAGCCAGCATGAA
  GCGAGCTCACCCCGAGTACAGCTCCTCGGACAGCGAGCTGGACGAGACCATCGAGGTGGA
  GAAGGAGAGTGCGGACGAGAATGGAAACTTGAGTTCGGCTCTAGGTTCCATGTCCCCAAC
  TACATCTTCCCAGATTTTGGCCAGAAAAAGACGGAGAGGAATAATTGAGAAGCGCCGACG
  AGACCGGATCAATAACAGTTTGTCTGAGCTGAGAAGGCTGGTACCCAGTGCTTTTGAGAA
  GCAGGTAATGGAGCAAGGATCTGCTAAGCTAGAAAAAGCCGAGATCCTGCAGATGACCGT
  GGATCACCTGAAAATGCTGCATACGGCAGGAGGGAAAGGTTACTTTGACGCGCACGCCCT
  TGCTATGGACTATCGGAGTTTGGGATTTCGGGAATGCCTGGCAGAAGTTGCGCGTTATCT
  GAGCATCATTGAAGGACTAGATGCCTCTGACCCGCTTCGAGTTCGACTGGTTTCGCATCT
  CAACAACTACGCTTCCCAGCGGGAAGCCGCGAGCGGCGCCCACGCGGGCCTCGGACACAT
  TCCCTGGGGGACCGTCTTCGGACATCACCCGCACATCGCGCACCCGCTGTTGCTGCCCCA
  GAACGGCCCACGGGAACGCGGGCACCACGGCCTCACCCACGGAACCCGCACCACCAGGGC
  AGGCTGGGCTCGGCACATCCGGAGGCGCCTGCTTTGCGAGCGCCCCTAGCGCAGCCTCGA
  CCGTGCTCCCTGTGGTCACCTCCGCCTCAAACTGTCGCCGCCTCTGCTCTCTCAGTGGCC
  TCCCTGTCGGCTTCCCCTTTCTCTTTCGGCTCCTTCCACTA
  
• Restriction Sites: Please inquire
• ACCN: NM_001040708
• ORF Size: 927 bp
• Insert Size: 1400
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.

Reference Data

• RefSeq: NM_001040708.1, NP_001035798.1
• RefSeq Size: 2331
• RefSeq ORF: 927
• Locus ID: 23462
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: This gene encodes a nuclear protein belonging to the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcriptional repressors. Expression of this gene is induced by the Notch and c-Jun signal transduction pathways. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2), also known as HESR1-12nt, uses an alternate in-frame splice site in the central coding region, compared to variant 1, resulting in a longer protein (isoform b).