AKR1B10 (NM_020299) Human Untagged Clone

CAT#: SC311363

AKR1B10 (untagged)-Human aldo-keto reductase family 1, member B10 (aldose reductase) (AKR1B10)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: AKR1B10
• Synonyms: AKR1B11; AKR1B12; ALDRLn; ARL-1; ARL1; HIS; HSI
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_020299 edited
  CCTGAGCTCAGGAGTTTGAGACCAGCCTGTCTCTACTAACAATATAAAAATTAGCTGGGA
  GTCACGGTGGGCGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATTGCTTGA
  ACCCAGGAGACAGAGGTTGTAGTGAGCTGAGATCGCACCACTGCACTCTAGCCTTGGCAA
  CAGTGCAAGACTGTCTCAAAAACAGCAACAGAGAGCAGGACGTGAGACTTCTACCTGCTC
  ACTCAGAATCATTTCTGCACCAACCATGGCCACGTTTGTGGAGCTCAGTACCAAAGCCAA
  GATGCCCATTGTGGGCCTGGGCACTTGGAAGTCTCCTCTTGGCAAAGTGAAAGAAGCAGT
  GAAGGTGGCCATTGATGCAGGATATCGGCACATTGACTGTGCCTATGTCTATCAGAATGA
  ACATGAAGTGGGGGAAGCCATCCAAGAGAAGATCCAAGAGAAGGCTGTGAAGCGGGAGGA
  CCTGTTCATCGTCAGCAAGTTGTGGCCCACTTTCTTTGAGAGACCCCTTGTGAGGAAAGC
  CTTTGAGAAGACCCTCAAGGACCTGAAGCTGAGCTATCTGGACGTCTATCTTATTCACTG
  GCCACAGGGATTCAAGTCTGGGGATGACCTTTTCCCCAAAGATGATAAAGGTAATGCCAT
  CGGTGGAAAAGCAACGTTCTTGGATGCCTGGGAGGCCATGGAGGAGCTGGTGGATGAGGG
  GCTGGTGAAAGCCCTTGGGGTCTCCAATTTCAGCCACTTCCAGATCGAGAAGCTCTTGAA
  CAAACCTGGACTGAAATATAAACCAGTGACTAACCAGGTTGAGTGTCACCCATACCTCAC
  ACAGGAGAAACTGATCCAGTACTGCCACTCCAAGGGCATCACCGTTACGGCCTACAGCCC
  CCTGGGCTCTCCGGATAGACCTTGGGCCAAGCCAGAAGACCCTTCCCTGCTGGAGGATCC
  CAAGATTAAGGAGATTGCTGCAAAGCACAAAAAAACCGCAGCCCAGGTTCTGATCCGTTT
  CCATATCCAGAGGAATGTGATTGTCATCCCCAAGTCTGTGACACCAGCACGCATTGTTGA
  GAACATTCAGGTCTTTGACTTTAAATTGAGTGATGAGGAGATGGCAACCATACTCAGCTT
  CAACAGAAACTGGAGGGCCTGTAACGTGTTGCAATCCTCTCATTTGGAAGACTATCCCTT
  CGATGCAGAATATTGAGGTTGAATCTCCTGGTGAGATTATACAGGAGATTCTCTTTCTTC
  GCTGAAGTGTGACTACCTCCACTCATGTCCCATTTTAGCCAAGCTTATTTAAGATCACAG
  TGAACTTAGTCCTGTTATAGACGAGAATCGAGGTGCTGTTTTAGACATTTATTTCTGTAT
  GTTCAACTAGGATCAGAATATCACAGAAAAGCATGGCTTGAATAAGGAAATGACAATTTT
  TTCCACTTATCTGATCAGAACAAATGTTTATTAAGCATCAGAAACTCTGCCAACACTGAG
  GATGTAAAGATCAATAAAAAAAATAATAATCATAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_020299 unedited
  GAGTAGTATTTTGTATACGACTACTATAGGGCGGCCGCGAATCGGCACGAGGCCTGAGCT
  CAGGAGTTTGAGACCAGCCTGTCTCTACTAACAATATAAAAATTAGCTGGGAGTCACGGT
  GGGCGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATTGCTTGAACCCAGGA
  GACAGAGGTTGTAGTGAGCTGAGATCGCACCACTGCACTCTAGCCTTGGCAACAGTGCAA
  GACTGTCTCAAAAACAGCAACAGAGAGCAGGACGTGAGACTTCTACCTGCTCACTCAGAA
  TCATTTCTGCACCAACCATGGCCACGTTTGTGGAGCTCAGTACCAAAGCCAAGATGCCCA
  TTGTGGGCCTGGGCACTTGGAAGTCTCCTCTTGGCAAAGTGAAAGAAGCAGTGAAGGTGG
  CCATTGATGCAGGATATCGGCACATTGACTGTGCCTATGTCTATCAGAATGAACATGAAG
  TGGGGGAAGCCATCCAAGAGAAGATCCAAGAGAAGGCTGTGAAGCGGGAGGACCTGTTCA
  TCGTCAGCAAGTTGTGGCCCACTTTCTTTGAGAGACCCCTTGTGAGGAAAGCCTTTGAGA
  AGACCCTCAAGGACCTGAAGCTGAGCTATCTGGACGTCTATCTTATTCACTGGCCACAGG
  GATTCAAGTCTGGGGATGACCTTTTCCCCAAAGATGATAAAGTAATGCCATCGGTGGAAA
  AGCAACGTTCTTGGATGCCTGGAGCCATGGAGGAGCTGGTGGATGAGGGGCTGGTGAAAG
  CCCTTGGGGTCTCCAATTTCAGCCACTTCAGATCGAGAAGCTCTTGAACAACCTGGACTG
  AAATATTAACCAGTGACTACCAGTTGAGTGTCACCATACCTCACACAGGAGAAACTGATC
  CAGTACTGCCACTCAAGGCATCACCGTTACGGCTACAGGCCCCCTGGG
  
• Restriction Sites: Please inquire
• ACCN: NM_020299
• ORF Size: 951 bp
• Insert Size: 1600
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.

Reference Data

• RefSeq: NM_020299.3, NP_064695.2
• RefSeq Size: 1551
• RefSeq ORF: 951
• Locus ID: 57016
• Domains: aldo_ket_red
• Protein Families: Druggable Genome
• Protein Pathways: Butanoate metabolism, Fructose and mannose metabolism, Linoleic acid metabolism, Metabolic pathways
• Gene Summary: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member can efficiently reduce aliphatic and aromatic aldehydes, and it is less active on hexoses. It is highly expressed in adrenal gland, small intestine, and colon, and may play an important role in liver carcinogenesis. [provided by RefSeq, Jul 2008]