SCF (KITLG) (NM_003994) Human Untagged Clone

CAT#: SC312617

KITLG (untagged)-Human KIT ligand (KITLG), transcript variant a


  "NM_003994" in other vectors (6)

Reconstitution Protocol

USD 420.00

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol KITLG
Synonyms DCUA; DFNA69; FPH2; FPHH; Kitl; KL-1; MGF; SCF; SF; SHEP7; SLF
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_003994 edited
GAACAGCTAAACGGAGTCGCCACACCACTGTTTGTGCTGGATCGCAGCGCTGCCTTTCCT
TATGAAGAAGACACAAACTTGGATTCTCACTTGCATTTATCTTCAGCTGCTCCTATTTAA
TCCTCTCGTCAAAACTGAAGGGATCTGCAGGAATCGTGTGACTAATAATGTAAAAGACGT
CACTAAATTGGTGGCAAATCTTCCAAAAGACTACATGATAACCCTCAAATATGTCCCCGG
GATGGATGTTTTGCCAAGTCATTGTTGGATAAGCGAGATGGTAGTACAATTGTCAGACAG
CTTGACTGATCTTCTGGACAAGTTTTCAAATATTTCTGAAGGCTTGAGTAATTATTCCAT
CATAGACAAACTTGTGAATATAGTGGATGACCTTGTGGAGTGCGTGAAAGAAAACTCATC
TAAGGATCTAAAAAAATCATTCAAGAGCCCAGAACCCAGGCTCTTTACTCCTGAAGAATT
CTTTAGAATTTTTAATAGATCCATTGATGCCTTCAAGGACTTTGTAGTGGCATCTGAAAC
TAGTGATTGTGTGGTTTCTTCAACATTAAGTCCTGAGAAAGGGAAGGCCAAAAATCCCCC
TGGAGACTCCAGCCTACACTGGGCAGCCATGGCATTGCCAGCATTGTTTTCTCTTATAAT
TGGCTTTGCTTTTGGAGCCTTATACTGGAAGAAGAGACAGCCAAGTCTTACAAGGGCAGT
TGAAAATATACAAATTAATGAAGAGGATAATGAGATAAGTATGTTGCAAGAGAAAGAGAG
AGAGTTTCAAGAAGTGTAATTGTGGCTTGTATCAACACTGTTACTTTCGTACATTGGCTG
GTAACAGTTCATGTTTGCTTCATAAATGAAGCAGCTTTAAACAAATTCATATTCTGTCTG
GAGTGACAGACCACATCTTTATCTGTTCTTGCTACCCATGACTTTATATGGATGATTCAG
AAATTGGAACAGAATGTTTTACTGTGAAACTGGCACTGAATTAATCATCTATAAAGAAGA
ACTTGCATGGAGCAGGACTCTATTTTAAGGACTGCGGGACTTGGGTCTCATTTAGAACTT
GCAGCTGATGTTGGAAGAGAAAGCACGTGTCTCAGACTGCATGCACCATTTGCATGGCTC
CAGAAATGTCTAAATGCTGAAAAAACACCTAGCTTTATTCTTCAGATACAAACTGCAGCC
TGTAGTTATCCTGGTCTCTGCAAGTAGATTTCAGCTTGGATAGTGAGGGTAACAATTTTT
CTCAAAGGGATCTAGAAAAAATGTTTAAAACTCAGTAGTGTCAGCCACTGTACAGTGTAG
AAAGCAGTGGGAACTGTGATTGGATTTGGCAACATGTCAGCTTTATAGTTGCCGATTAGT
GATATGGGTCTGATTTCGATCTCTTCCTGATGTAAACCATGCTCACCCATATCCCACTAT
ACAAATGCAAATGGTTGCCTGGTTCCATTTATGCAAGGGAGCCAGTACTGAATTATGCCT
TGGCAGAGGGGAGACTCCAAAAGAGTCATCGCAGGAAGAAGTTAAGAACACTGAACATCA
GAACAGTCTGCCAAGAAGGACATTGGCATCCTGGGAAAGTCCGCCTTTTCCCTTGACCAC
TATAGGGTGTATAAATCGTGTTTGCAAAATGTGTTATGATGTGTTTATATTCTAAAACTA
TTACAGAGCTATGTAAAGGGACTTAGGAGAAAATGCTGAATGTAAGATGGTCCCATTTCA
ATTTCCACCATGGGAGAGCCTAAAAATAAATTATGACATTTAGTATCTAAGGTTAGAAAA
CCACGCCCACATGCTAATATGGGTGTTGAAAACTAGGTTACTTATAATGCAAGGAATCAG
GAAACTTTAGTTATTTATAGTATAATCACCATTATCTGTTTAAAGGATCCATTTAGTTAA
AATCGGGCACTCTATATTCATTAAGGTTTATGAATTAAAAAGAAAGCTTTATGTAGTTAT
GCATGTCAGTTTGCTATTTAAAATGTGTGACAGTGTTTGTCATATTAAGAGTGAATTTGG
CAGGAATTCCCAAGATGGACATTGTGCTTTTAAACTAGAACTTGTAAGACATTATGTGAA
TATCCCTTGCCAATTTTTTTTATAATAAGAAAACATCTGACTAAAGTCAAAGAATGATTT
CTTATGGTTTATTTTGATGAAAGTTCTTTTAACATGTCTTGAATGTACACATAAAGGAAT
CCAAAGCTTTCCATTCTAACTTAATCTTTGTGATAACATTATTGCCATGTTCTACAACCG
TAAGATGACAGTTTTCAATGTAGTGACACAAAAGGGCATGAAAAACTAACTGCTAGCTTT
CCTTTCATTTCAAAAGTCCAAGAATTTCTAGTATATTTGGATTTTAGCTTCTGTTCAAAG
CAAATCCAGATGCAACTCCAGTAAGTGGCCTTTGCTCTTTTTTGTACCAAAGAGCCCAGA
TGATTCCTACAGTCCCTTTCTTCTCTAACATGCTGTGGTTCCTTAAATATGAGTAATTTC
TCTAAGATATAACCCAGGTGCTTTGAGAAGCTGCATTAAGGTGTTCAGGCCCTCAGATAT
CACATGGTACACTTGATTAGTAATAAAACCAGAGATCAATTTAAATTGCTGATAGGTCCT
GTCTCAGTGTGTGGCATTGACTGTTTTCAGGAAAATAGATACAGATTAATATGAGTTATG
CGTGTAGGTTGTGTATAGATTGAGAAGATAGATACTTCTCAATCTAGTAGTTTGATTTAT
TTAACCAATGGTTTCAGTTTGCTTGAGCATATGAAAATCCTGCTTAATGTGCTTAAGAGT
ATAATAAATGTGTACTTTTGTCCTCAAACCTAGTAGCTGGGTTTTAACACTCATGGACAT
GGTCTTAATCAATGGAGTTAAATAAACAAATTCAGCAAGTTATTAAATCTGACATGGTAG
GAGAGGGGAGATGTGTCCTGCTTATTAAATGTGTTGGTCCATTGAAAGTTACATGGATTG
CCAATTTTTAAAACACTAAAGTTGAATAAAATGCATGAACAATAGAAAAATGCTGAACAT
TATTTTGGATGCTAGCTGCTTGGACATTAACTGTGTTATTTCTGCTTTGAGATGAAAATA
TATATTTATCTTTGCTTATTTTATCCCAGATGTGTTCTGAATATCCTTCTTCATAAATCA
TGGAAAACTCACTGCTGAGATAGTAAACCATGAAATCGCCTTTTCAGTTGGTGCCATGTA
TCTGACAGTTCCATCTTGGAAGGTTTCAAAATTACCTTTTAAAATGATCTCAGAAGTCTG
TAGATTCTCAATGATACTGAAAGCTTTGCACCTCTTTGGTAGAAACCAGGTCTATTTAGA
AAATGGCTTTATGATAAATGTTGCCTCCTGAGTGATAATGAAGTGTTCCTGGATATTGTA
TTGTAATTTAATGTGCTTACCACACTGCCACATTTTAATGAGTCAGAGAAAAATTAATTT
TTCTTCAATACAATAATAGAACAAGTAGCCTATTCTCTTAAAAAGTATGTGAAAAGAAAA
TTATGAAAAAATATGCATACCTAATGAAGTATTGGTTTTAGTAAGAATTAAATACATTTC
ATTGAGCTTTAAAGTACTTTGGAGAAACTTTGGGGCACGTTTTCCTACTCTAATTCAACT
AAAGTTATAAATAAAGAGAAAAACTCATTCAGAAATCATGGATTTTAAAAATATTTTACT
GCAGCCAAGTTTTCATTTCAAAATGTAATTTCAGTTTGGAGCTTTTAGGCATTATGTATA
TTTAAAAAATATATTCTTCAAAAATGCATTTTGGCATGGTGGGATGGATGTTGCAAAAGA
TATCCGGAGCCTCCAGTCTGTCATTAACTGATATGGTAAATCACCTCTCTTCTTTGGGTC
TCAATTTTTTATTTATCTATATGGTAAACTCAGAGATCACTCCTTAGGGGTGAGTCCTAT
TGCAATATGACCGACAAAGAAGACAAAATAGCATTGAAACTAACCCATACAAAATATCCA
ACTCTGGATTCTGTGAATAAGTATCTTGACCATAAAAAGTCATTGCTGTTCTTGTTTCTA
ATGTAAATAGTGTCCATTAGTAAAAGTGAAATTCAGTCTTAAGTAGGGTGAATTGGATCA
CCATTTACACAAGAGATGGCTTTTTCCTTTGCTTGAATAAACATTTTGGATCACCTCCAA
AGAATGAAAACCAGTAGTACGTTTTAGTCATATTAGTCAGGATGAGAAACTATAAGATGT
GTGTAACATTTGGAAATGCACCAAAGTGAGCGTTTAAATCTTCTCATTTTATTGAAAACT
AAGAGCAGAAAATGTAAAATGCTCATGAAGGTTTTGAATGCCAAAAGATATTTTAGAATC
AATTTATAAAGGGGTAATTCATTAATTACACTTTAAAATTGGAAAGTGGGATAAGAAATC
TAAAGTAAACCAGCTTATCTTTGAAACAATATTATTTTGAAATTGGCTTTAAAATAAAAC
CATTCAGATTGAAATTCTAATTAGCTCATTTGTGGAGTTTGATCACACAATTCATAATGT
TGCTGCTTTCCATTAACTAGTCTTGAAATGCCTTTGTTTGTAAAAATAAAATAATGGTAC
TTTCATTTTATAACAAGGTGTTTTTTTCAAGAAATAATCCATGCTAAAATGGATATTTGT
GATCCTGAAATGTTTACTAAGCATTGTAAATTTATTTATAACTGCCATCTCCAACTACAT
CCTTATGATGTTTTTAACAATAAAATTAAAACAACTGTTAAACTAAAAACCACACCGTTT
TCCAGTACTTGATCTCTGAGCTACAATACTCACTAAATATAATTTTCCAATCAAAATATT
CTATTCTATATTCTAAGGGTTAATATGTGATTATAGTGTCCACTTGCCACCATTTTTTTA
AATCAATGGACTTGAAAAGTATTAATTTAGATGGATGCGCAGATATACCCTCAGTTCAGT
CATAGATTGGAGTTTGCATATAATAATGTAAATGTATGTCGACACTATTCTAAATAGTTC
TATTATGACTGAAATTTAATTAAATAAAAAAGGTTGTAAAATGTGATGTGTATGTGTATA
TACTGTATGTGTACTTTTTAAAATAGGTGTATGTCCCAACCCTTTTTTATACAGGTTTGA
ATTTAAAATTACATGATATATACATATACTTTATTGTTCTAAATAAAGAATTTTATGCAC
TCTCAAAAAAAAAAAAAAAAAAAAAAAAAAA
Restriction Sites Please inquire     
ACCN NM_003994
Insert Size 5200 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation The ORF of this clone has been fully sequenced and found to be a perfect match to NM_003994.4.
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_003994.4, NP_003985.2
RefSeq Size 5351 bp
RefSeq ORF 738 bp
Locus ID 4254
Cytogenetics 12q21.32
Domains SCF
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Melanogenesis, Pathways in cancer
Gene Summary 'This gene encodes the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]'
Transcript Variant: This variant (a) lacks an alternate in-frame exon, compared to variant b. Isoform a lacks the primary proteolytic-cleavage site; as a result, the protein encoded by isoform a is largely a membrane bound product. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

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