OGR1 (GPR68) (NM_003485) Human Untagged Clone

CAT#: SC313197

GPR68 (untagged)-Human G protein-coupled receptor 68 (GPR68), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: GPR68
• Synonyms: AI2A6; GPR12A; OGR1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_003485 edited
  GATGGCGGTGGAGAGACAGGCCCAGTCCCTGAGCCCATGAGGAGTGTGGCCCCTTCAGGC
  CCAAAGATGGGGAACATCACTGCAGACAACTCCTCGATGAGCTGTACCATCGACCATACC
  ATCCACCAGACGCTGGCCCCGGTGGTCTATGTTACCGTGCTGGTGGTGGGCTTCCCGGCC
  AACTGCCTGTCCCTCTACTTCGGCTACCTGCAGATCAAGGCCCGGAACGAGCTGGGCGTG
  TACCTGTGCAACCTGACGGTGGCCGACCTCTTCTACATCTGCTCGCTGCCCTTCTGGCTG
  CAGTACGTGCTGCAGCACGACAACTGGTCTCACGGCGACCTGTCCTGCCAGGTGTGCGGC
  ATCCTCCTGTACGAGAACATCTACATCAGCGTGGGCTTCCTCTGCTGCATCTCCGTGGAC
  CGCTACCTGGCTGTGGCCCATCCCTTCCGCTTCCACCAGTTCCGGACCCTGAAGGCGGCC
  GTCGGCGTCAGCGTGGTCATCTGGGCCAAGGAGCTGCTGACCAGCATCTACTTCCTGATG
  CACGAGGAGGTCATCGAGGACGAGAACCAGCACCGCGTGTGCTTTGAGCACTACCCCATC
  CAGGCATGGCAGCGCGCCATCAACTACTACCGCTTCCTGGTGGGCTTCCTCTTCCCCATC
  TGCCTGCTGCTGGCGTCCTACCAGGGCATCCTGCGCGCCGTGCGCCGGAGCCACGGCACC
  CAGAAGAGCCGCAAGGACCAGATCCAGCGGCTGGTGCTCAGCACCGTGGTCATCTTCCTG
  GCCTGCTTCCTGCCCTACCACGTGTTGCTGCTGGTGCGCAGCGTCTGGGAGGCCAGCTGC
  GACTTCGCCAAGGGCGTTTTCAACGCCTACCACTTCTCCCTCCTGCTCACCAGCTTCAAC
  TGCGTCGCCGACCCCGTGCTCTACTGCTTCGTCAGCGAGACCACCCACCGGGACCTGGCC
  CGCCTCCGCGGGGCCTGCCTGGCCTTCCTCACCTGCTCCAGGACCGGCCGGGCCAGGGAG
  GCCTACCCGCTGGGTGCCCCCGAGGCCTCCGGGAAAAGCGGGGCCCAGGGTGAGGAGCCC
  GAGCTGTTGACCAAGCTCCACCCGGCCTTCCAGACCCCTAACTCGCCAGGGTCGGGCGGG
  TTCCCCACGGGCAGGTTGGCCTAGCCTGGGTCCTCCGCGGGTGGCTCCACGTGAGGCCTG
  AGCCTTCAGCCCACGGGCCTCAGGGCCTGCCGCCTCCTGCTTCCC
  
• Restriction Sites: Please inquire
• ACCN: NM_003485
• ORF Size: 1128 bp
• Insert Size: 1200
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_003485.2, NP_003476.2
• RefSeq Size: 1523
• RefSeq ORF: 1128
• Locus ID: 8111
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Gene Summary: The protein encoded by this gene is a G protein-coupled receptor for sphingosylphosphorylcholine. The encoded protein is a proton-sensing receptor, inactive at pH 7.8 but active at pH 6.8. Mutations in this gene are a cause of amelogenesis imperfecta. [provided by RefSeq, Feb 2017]
  Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 3. Variants 1-3 all encode the same protein. There is an upstream in-frame AUG (uAUG) present; however, translation is thought to begin from the annotated downstream AUG due to inhibition of the uAUG by a small overlapping open reading frame.