SORBS2 (AF396457) Human Untagged Clone

CAT#: SC313337

(untagged)-Human sorbin polypeptide mRNA, complete cds

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SORBS2
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for AF396457, the custom clone sequence may differ by one or more nucleotides
  ATGAAAGCAACAACACCTTTGCAGACAGTCGACCGGCCCAAGGACTGGTACAAGACGATG
  TTTAAGCAAATTCACATGGTGCACAAGCCGGATGATGACACAGACATGTATAATACTCCT
  ACACCTCACATGAAATATACATACAATGCAGGTCTGTACAACCCACCCTACAGTGCTCAG
  TCACACCCTGCTGCAAAGACCCAAACCTACAGACCTCTTTCCAAAAGCCACTCCGACAAC
  AGCCCCAATGCCTTTAAGGATGCGTCCTCCCCAGTGCCTCCCCCACATGTTCCACCTCCA
  GTCCCGCCGCTTCGACCAAGAGATCGGTCTTCAACAGAAAAGCATGACTGGGATCCTCCA
  GACAGAAAAGTGGACACAAGAAATTTCGGGTCTGAGCCAAGGAGTATTTTTGAATACGAG
  GACAGAAAAGTGGACACGAGAAAATTTCGATCGGAGCCACGGTCTATTTTTGAATACGAG
  CCTGGGAAGTCATCCATCCTGCAGCACGAACGACCCGTCTACCAGTCTTCCATAGACAGA
  AGCTTGGAAAGACCCAGCAGCTCTGCAAGCATGGCGGGTGACTTTAGAAAACGGAGGAAG
  AGTGAACCTGCAGTGGGCCCGCCCAGGGGCTTGGGGGATCACAGTTCAAGCAGGACCAGC
  CCCGGCCGGGCAGACCTCCCAGGATCAAGTTCCACCTTTACCACGTCTTTCATTAGTTCT
  TCTCCTTCCTCTCCCTCGAGAGCACAAGGTGGGGATGATAGCAAAATGTGTCCGCCCCTT
  TGCAGTTACTCGGGGCTCAATGGCTCGCCCTCTAGTGAGTTAGAGTGCTGCGGCGCTTAT
  AGAAGGCACTTGGACGTCCCCCAGGACTCTCAAAGGGCCATCACTTTCAAGAACGGCTGG
  CAAATGGCCCGGCAAAATGCAGAGATCTGGAGTAGCACTGAAGAGGCGGTTTCCCCCAAA
  ATCAAATCACGAAGCTGTGACGATCTCCTGAATGATGACTGCGGCAGCTTCCCAGACCCT
  AAAACCAAGTCAGAAAGCATGGGTTCTCTGTTATGTGACGAAGGCTCCAAAGAGAGCGAC
  CCCATGACGTGGACTTCCCCCTACATCCCGGAAGTGTGCGGGAACAGCAGAGAATTCATG
  TTAAGCAAATGGATATTCGTGGAATCTCTGGATGGAGGACCATTTTGGAAAGTGCTAAAG
  GAATATCTAGAGCGAGTGAGGAATCTA
  
• Restriction Sites: Please inquire
• ACCN: AF396457
• ORF Size: 1569 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: AF396457.1, AAK81860.1
• RefSeq Size: 1569
• RefSeq ORF: 1569
• Locus ID: 8470
• Domains: Sorb
• Gene Summary: Arg and c-Abl represent the mammalian members of the Abelson family of non-receptor protein-tyrosine kinases. They interact with the Arg/Abl binding proteins via the SH3 domains present in the carboxy end of the latter group of proteins. This gene encodes the sorbin and SH3 domain containing 2 protein. It has three C-terminal SH3 domains and an N-terminal sorbin homology (SoHo) domain that interacts with lipid raft proteins. The subcellular localization of this protein in epithelial and cardiac muscle cells suggests that it functions as an adapter protein to assemble signaling complexes in stress fibers, and that it is a potential link between Abl family kinases and the actin cytoskeleton. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]