Apc7 (ANAPC7) (NM_016238) Human Untagged Clone

CAT#: SC314026

ANAPC7 (untagged)-Human anaphase promoting complex subunit 7 (ANAPC7), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ANAPC7
• Synonyms: APC7
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_016238, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGACCCCGGCGACGCCGCCATTTTGGAGTCTTCCCTAAGGATCCTCTACCGGCTTTTCGAGTCAGTGC
  TGCCGCCGCTGCCCGCGGCTTTGCAGAGCAGGATGAATGTGATAGACCACGTGCGGGACATGGCGGCCGC
  GGGGCTGCACTCCAACGTGCGGCTCCTCAGCAGCTTGTTACTTACAATGAGTAATAACAACCCTGAGTTA
  TTCTCCCCACCTCAGAAGTACCAGCTTTTGGTGTATCATGCAGATTCTCTCTTTCATGATAAGGAATATC
  GGAATGCTGTGAGTAAGTATACCATGGCTTTACAGCAGAAGAAAGCGCTAAGTAAAACTTCAAAAGTGAG
  ACCTTCAACTGGAAATTCTGCATCTACTCCACAAAGTCAGTGTCTTCCATCTGAAATTGAAGTGAAATAC
  AAAATGGCTGAATGTTATACAATGCTAAAACAAGATAAAGATGCCATTGCTATACTTGATGGGATCCCTT
  CAAGACAAAGAACTCCCAAAATAAACATGATGCTGGCAAACCTGTACAAGAAGGCTGGTCAGGAGCGCCC
  TTCAGTCACCAGCTATAAGGAGGTGCTGAGGCAGTGCCCATTAGCCCTTGATGCCATTCTAGGCTTGTTG
  TCCCTTTCTGTAAAAGGGGCAGAGGTGGCATCCATGACAATGAATGTGATCCAAACCGTGCCTAACTTGG
  ACTGGCTCTCTGTGTGGATCAAAGCGTATGCTTTTGTGCACACTGGTGACAACTCAAGAGCAATCAGTAC
  CATCTGTTCACTAGAGAAAAAATCCTTATTGCGAGATAACGTGGACCTATTGGGAAGCTTGGCAGATCTG
  TACTTCAGAGCTGGAGACAATAAAAACTCTGTCCTCAAGTTTGAACAGGCACAGATGTTGGATCCTTATC
  TGATAAAAGGAATGGATGTATATGGCTACCTACTGGCACGAGAAGGGCGGCTAGAGGATGTTGAGAACCT
  TGGATGCCGCCTTTTCAATATCTCTGATCAGCATGCAGAACCGTGGGTGGTTTCTGGCTGTCACAGCTTC
  TATAGCAAACGCTACTCCCGGGCCCTCTATTTAGGAGCCAAGGCCATTCAGCTGAACAGTAATAGTGTTC
  AAGCTCTGCTACTTAAGGGAGCAGCACTTAGGAACATGGGCAGAGTCCAAGAAGCAATAATCCACTTTCG
  GGAGGCCATACGGCTCGCACCTTGTCGCTTAGATTGTTATGAAGGTCTTATCGAATGTTACTTAGCCTCC
  AACAGTATTCGAGAAGCAATGGTAATGGCTAACAACGTTTACAAAACTCTGGGAGCAAATGCACAGACCC
  TTACCCTTTTAGCCACCGTTTGTCTTGAAGACCCAGTGACACAGGAGAAAGCCAAAACATTATTAGATAA
  AGCCCTGACCCAAAGGCCAGATTACATTAAGGCTGTGGTGAAAAAAGCAGAACTACTTAGCAGAGAACAG
  AAATATGAAGATGGAATTGCTTTGCTGAGGAACGCACTGGCTAATCAGAGTGACTGTGTCCTGCATCGGA
  TCCTAGGAGATTTCCTTGTAGCTGTCAATGAGTATCAGGAGGCAATGGACCAGTATAGTATAGCACTAAG
  TTTGGACCCCAATGACCAGAAGTCTCTAGAGGGGATGCAGAAGATGGAGAAGGAGGAGAGTCCCACGGAT
  GCCACTCAGGAGGAGGATGTGGACGACATGGAAGGGAGTGGGGAAGAAGGGGACCTGGAGGGCAGCGACA
  GTGAGGCGGCCCAGTGGGCTGACCAGGAGCAGTGGTTCGGCATGCAGTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_016238
• ORF Size: 1800 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_016238.2, NP_057322.2
• RefSeq Size: 3070
• RefSeq ORF: 1800
• Locus ID: 51434
• Domains: TPR
• Protein Families: Druggable Genome
• Protein Pathways: Cell cycle, Oocyte meiosis, Progesterone-mediated oocyte maturation, Ubiquitin mediated proteolysis
• Gene Summary: This gene encodes a tetratricopeptide repeat containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for proper protein ubiquitination function of APC/C and for the interaction of APC/C with certain transcription coactivators. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).