ZRANB1 (NM_017580) Human Untagged Clone

CAT#: SC314486

ZRANB1 (untagged)-Human zinc finger, RAN-binding domain containing 1 (ZRANB1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ZRANB1
• Synonyms: TRABID
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_017580, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTCAGAACGTGGAATTAAGTGGGCTTGTGAATATTGTACGTATGAAAACTGGCCATCTGCAATCAAGT
  GTACTATGTGTCGTGCCCAAAGACCTAGTGGAACAATTATTACAGAAGATCCATTTAAAAGTGGTTCAAG
  TGATGTTGGTAGAGATTGGGATCCTTCCAGCACCGAAGGAGGAAGTAGTCCTTTGATATGTCCAGACTCT
  AGTGCAAGACCAAGGGTGAAATCTTCGTATAGCATGGAAAATGCAAATAAGTGGTCATGCCACATGTGTA
  CATATTTGAACTGGCCAAGAGCAATCAGATGTACCCAGTGCTTATCCCAACGTAGGACCAGGAGTCCTAC
  AGAATCTCCTCAGTCCTCAGGATCTGGCTCAAGACCAGTTGCTTTTTCTGTTGATCCTTGTGAGGAATAC
  AATGATAGAAATAAACTGAACACTAGGACACAGCACTGGACTTGCTCTGTTTGCACATATGAAAACTGGG
  CCAAGGCTAAAAGATGTGTTGTTTGTGATCATCCCAGACCTAATAACATTGAAGCAATAGAATTGGCAGA
  GACTGAAGAGGCTTCTTCAATAATAAATGAGCAAGACAGAGCTCGATGGAGGGGAAGTTGCAGTAGTGGT
  AATAGCCAAAGGAGATCACCTCCTGCTACGAAGCGGGACTCTGAAGTGAAAATGGATTTTCAGAGGATTG
  AATTGGCTGGTGCTGTGGGAAGCAAGGAGGAACTTGAAGTAGACTTTAAAAAACTAAAGCAAATTAAAAA
  CAGGATGAAAAAGACTGATTGGCTCTTCCTCAATGCTTGTGTGGGGGTTGTAGAAGGTGATTTAGCTGCC
  ATAGAAGCATACAAGTCATCAGGAGGAGACATTGCACGTCAGCTCACCGCAGATGAAGTACGCTTGCTGA
  ATCGTCCTTCTGCCTTTGATGTTGGCTATACTCTTGTACACTTGGCTATACGTTTTCAGAGGCAGGATAT
  GCTAGCAATATTGCTTACAGAGGTGTCTCAACAAGCAGCAAAGTGTATTCCAGCAATGGTGTGTCCTGAA
  CTGACAGAACAAATCCGGAGAGAGATAGCTGCCTCTCTTCATCAGAGAAAGGGGGATTTTGCTTGCTATT
  TTCTGACTGACCTTGTAACATTTACATTGCCAGCAGATATTGAAGATTTGCCCCCAACAGTCCAAGAAAA
  ATTATTTGATGAGGTGCTTGATAGAGACGTTCAAAAAGAATTAGAAGAAGAATCTCCAATTATTAACTGG
  TCCTTGGAATTGGCTACACGTTTGGACAGTCGACTGTATGCACTTTGGAACCGGACTGCAGGAGACTGCC
  TACTTGATTCAGTTCTACAAGCTACCTGGGGCATCTATGACAAGGACTCAGTGCTTCGGAAAGCCCTGCA
  TGACAGCCTGCATGACTGTTCACATTGGTTTTACACACGCTGGAAAGATTGGGAATCATGGTATTCTCAG
  AGCTTTGGTTTACATTTTTCCTTGAGAGAAGAACAGTGGCAAGAAGACTGGGCATTTATACTCTCTCTTG
  CTAGTCAGCCTGGAGCAAGCTTGGAGCAGACGCACATTTTTGTACTGGCACATATTCTTAGACGACCAAT
  TATAGTTTATGGAGTAAAATATTACAAGAGTTTCCGGGGAGAAACTTTAGGATATACTCGGTTTCAAGGT
  GTTTATCTGCCTTTGTTGTGGGAACAGAGTTTTTGTTGGAAAAGTCCGATTGCTCTGGGTTATACGAGGG
  GCCACTTCTCTGCTTTGGTTGCCATGGAAAATGATGGCTATGGCAACCGAGGTGCTGGTGCTAATCTCAA
  TACCGATGATGATGTCACCATCACATTTTTGCCTCTGGTTGACAGTGAAAGGAAGCTACTCCATGTGCAC
  TTCCTTTCTGCTCAGGAGCTAGGTAATGAGGAACAGCAAGAAAAACTGCTCAGGGAGTGGCTGGACTGCT
  GTGTGACGGAGGGGGGAGTTCTGGTTGCCATGCAGAAGAGTTCTCGGCGGCGAAATCACCCCCTGGTCAC
  TCAGATGGTAGAAAAATGGCTTGACCGCTACCGACAGATCCGGCCGTGTACATCCCTGTCTGATGGAGAG
  GAAGATGAGGATGATGAAGATGAATGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_017580
• ORF Size: 2127 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_017580.2, NP_060050.2
• RefSeq Size: 4942
• RefSeq ORF: 2127
• Locus ID: 54764
• Domains: zf-RanBP
• Protein Families: Druggable Genome
• Gene Summary: Specifically hydrolyzes 'Lys-29'-linked and 'Lys-33'-linked diubiquitin. Also cleaves 'Lys-63'-linked chains, but with 40-fold less efficiency compared to 'Lys-29'-linked ones. Positive regulator of the Wnt signaling pathway that deubiquitinates APC protein, a negative regulator of Wnt-mediated transcription. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration. May also modulate TNF-alpha signaling. [UniProtKB/Swiss-Prot Function]