FOXP2 (NM_014491) Human Untagged Clone

CAT#: SC314508

FOXP2 (untagged)-Human forkhead box P2 (FOXP2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: FOXP2
• Synonyms: CAGH44; SPCH1; TNRC10
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_014491 edited
  ATGATGCAGGAATCTGCGACAGAGACAATAAGCAACAGTTCAATGAATCAAAATGGAATG
  AGCACTCTAAGCAGCCAATTAGATGCTGGCAGCAGAGATGGAAGATCAAGTGGTGACACC
  AGCTCTGAAGTAAGCACAGTAGAACTGCTGCATCTGCAACAACAGCAGGCTCTCCAGGCA
  GCAAGACAACTTCTTTTACAGCAGCAAACAAGTGGATTGAAATCTCCTAAGAGCAGTGAT
  AAACAGAGACCACTGCAGGTGCCTGTGTCAGTGGCCATGATGACTCCCCAGGTGATCACC
  CCTCAGCAAATGCAGCAGATCCTTCAGCAACAAGTCCTGTCTCCTCAGCAGCTACAAGCC
  CTTCTCCAACAACAGCAGGCTGTCATGCTGCAGCAGCAACAACTACAAGAGTTTTACAAG
  AAACAGCAAGAGCAGTTACATCTTCAGCTTTTGCAGCAGCAGCAGCAACAGCAGCAGCAG
  CAACAACAGCAGCAACAACAGCAGCAGCAACAACAACAACAACAGCAGCAACAACAGCAG
  CAGCAGCAGCAACAGCAGCAGCAGCAGCAACAGCATCCTGGAAAGCAAGCGAAAGAGCAG
  CAGCAGCAGCAGCAGCAGCAACAGCAATTGGCAGCCCAGCAGCTTGTCTTCCAGCAGCAG
  CTTCTCCAGATGCAACAACTCCAGCAGCAGCAGCATCTGCTCAGCCTTCAGCGTCAGGGA
  CTCATCTCCATTCCACCTGGCCAGGCAGCACTTCCTGTCCAATCGCTGCCTCAAGCTGGC
  TTAAGTCCTGCTGAGATTCAGCAGTTATGGAAAGAAGTGACTGGAGTTCACAGTATGGAA
  GACAATGGCATTAAACATGGAGGGCTAGACCTCACTACTAACAATTCCTCCTCGACTACC
  TCCTCCAACACTTCCAAAGCATCACCACCAATAACTCATCATTCCATAGTGAATGGACAG
  TCTTCAGTTCTAAGTGCAAGACGAGACAGCTCGTCACATGAGGAGACTGGGGCCTCTCAC
  ACTCTCTATGGCCATGGAGTTTGCAAATGGCCAGGCTGTGAAAGCATTTGTGAAGATTTT
  GGACAGTTTTTAAAGCACCTTAACAATGAACACGCATTGGATGACCGAAGCACTGCTCAG
  TGTCGAGTGCAAATGCAGGTGGTGCAACAGTTAGAAATACAGCTTTCTAAAGAACGCGAA
  CGTCTTCAAGCAATGATGACCCACTTGCACATGCGACCCTCAGAGCCCAAACCATCTCCC
  AAACCTCTAAATCTGGTGTCTAGTGTCACCATGTCGAAGAATATGTTGGAGACATCCCCA
  CAGAGCTTACCTCAAACCCCTACCACACCAACGGCCCCAGTCACCCCGATTACCCAGGGA
  CCCTCAGTAATCACCCCAGCCAGTGTGCCCAATGTGGGAGCCATACGAAGGCGACATTCA
  GACAAATACAACATTCCCATGTCATCAGAAATTGCCCCAAACTATGAATTTTATAAAAAT
  GCAGATGTCAGACCTCCATTTACTTATGCAACTCTCATAAGGCAGGCTATCATGGAGTCA
  TCTGACAGGCAGTTAACACTTAATGAAATTTACAGCTGGTTTACACGGACATTTGCTTAC
  TTCAGGCGTAATGCAGCAACTTGGAAGAATGCAGTACGTCATAATCTTAGCCTGCACAAG
  TGTTTTGTTCGAGTAGAAAATGTTAAAGGAGCAGTATGGACTGTGGATGAAGTAGAATAC
  CAGAAGCGAAGGTCACAAAAGATAACAGGAAGTCCAACCTTAGTAAAAAATATACCTACC
  AGTTTAGGCTATGGAGCAGCTCTTAATGCCAGTTTGCAGGCTGCCTTGGCAGAGAGCAGT
  TTACCTTTGCTAAGTAATCCTGGACTGATAAATAATGCATCCAGTGGCCTACTGCAGGCC
  GTCCACGAAGACCTCAATGGTTCTCTGGATCACATTGACAGCAATGGAAACAGTAGTCCG
  GGCTGCTCACCTCAGCCGCACATACATTCAATCCACGTCAAGGAAGAGCCAGTGATTGCA
  GAGGATGAAGACTGCCCAATGTCCTTAGTGACAACAGCTAATCACAGTCCAGAATTAGAA
  GACGACAGAGAGATTGAAGAAGAGCCTTTATCTGAAGATCTGGAATGA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_014491 unedited
  GCAAGGGATCCCAGGGAGTTGCTGTGGGCGGGAGACTGAAGATTGAAGTAAAGTATTAAG
  TCATGATGCAGGAATCTGCGACAGAGACAATAAGCAACAGTTCAATGAATCAAAATGGAA
  TGAGCACTCTAAGCAGCCAATTAGATGCTGGCAGCAGAGATGGAAGATCAAGTGGTGACA
  CCAGCTCTGAAGTAAGCACAGTAGAACTGCTGCATCTGCAACAACAGCAGGCTCTCCAGG
  CAGCAAGACAACTTCTTTTACAGCAGCAAACAAGTGGATTGAAATCTCCTAAGAGCAGTG
  ATAAACAGAGACCACTGCAGGTGCCTGTGTCAGTGGCCATGATGACTCCCCAGGTGATCA
  CCCCTCAGCAAATGCAGCAGATCCTTCAGCAACAAGTCCTGTCTCCTCAGCAGCTACAAG
  CCCTTCTCCAACAACAGCAGGCTGTCATGCTGCAGCAGCAACAACTACAAGAGTTTTACA
  AGAAACAGCAAGAGCAGTTACATCTTCAGCTTTTGCAGCAGCAGCAGCAACAGCAGCAGC
  AGCAACAACAGCAGCAACAACAGCAGCAGCAACAACAACAACAACAGCAGCAACAACAGC
  AGCAGCAGCAGCAACAGCAGCAGCAGCAGCACCAGCATCCTGGAAAAGCAGCGANAGAGC
  AGCAGCAGCAGCAGCAGCAGCAACAGCAATTGGCAGCCCAGCAGCTTGGTCTTCAGCAGC
  AGCTTCTCCAGATGGGCACACTNCAGCAGCAGCAGCATCTGCTCAGCCTTCAGCGTCAGG
  GACTCATCTNCATTTCACCTGGNCAGGCAGNACTTNCTGTCCAATCGCTGC
  
• Restriction Sites: Please inquire
• ACCN: NM_014491
• ORF Size: 2148 bp
• Insert Size: 4700
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_014491.1, NP_055306.1
• RefSeq Size: 2472
• RefSeq ORF: 2148
• Locus ID: 93986
• Domains: FH
• Protein Families: Transcription Factors
• Gene Summary: This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene. [provided by RefSeq, Feb 2010]
  Transcript Variant: This variant (1) lacks an in-frame exon in the 5' coding region, as compared to variant 2. The resulting isoform (I) is shorter than isoform II. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.