PCDHA12 (NM_031864) Human Untagged Clone

CAT#: SC314710

PCDHA12 (untagged)-Human protocadherin alpha 12 (PCDHA12), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PCDHA12
• Synonyms: PCDH-ALPHA12
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_031864, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGTGATTATCGGACCAAGAGGCCCGGGATCCCAGCGTCTGCTGCTCTCGCTTCTGCTCCTTGCAGCCT
  GGGAGGTGGGGAGCGGCCAGCTCCACTACTCCGTCTACGAGGAGGCCAAACACGGCACCTTCGTGGGCCG
  CATCGCTCAGGACCTGGGGCTGGAGCTGGCGGAGCTGGTGCCGCGCCTGTTCCGGGTGGCGTCCAAAAGA
  CACGGGGACCTTCTGGAGGTAAATCTGCAGAATGGCATTTTGTTTGTGAATTCTCGGATCGACCGCGAGA
  AGCTGTGCGGGCGGAGCGCGGAGTGCAGTATCCACCTGGAGGTGATCGTGGACAGGCCGCTGCAGGTTTT
  CCATGTGGACGTGGAGGTGAAGGACATTAACGACAACCCGCCGGTGTTCAGAGAAAGGGAACAAAAGGTA
  CCTGTTTCTGAATCTGCGCCTCTGGACTCTCATTTTCCTCTAGAGGGCGCTTCTGATGCGGATATCGGCG
  TAAACTCTCTTTTGACCTATGCGTTAAGTCTAAATGAGAATTTTGAGCTTAAAATAAAAACAAAAAAAGA
  TAAAAGTATATTGCCTGAATTAGTTCTTCGGAAGTTATTGGACAGAGAGCAAACGCCAAAACTCAATTTA
  TTGCTGATGGTAATCGATGGCGGTAAACCAGAACTAACAGGGTCTGTCCAGATTCAAATAACCGTCCTGG
  ATGTGAATGACAATGGTCCGGCGTTTGATAAGCCCAGCTATAAAGTAGTGTTGTCTGAAAATGTCCAAAA
  CGACACAAGAGTGATCCAACTAAATGCTTCCGATCCAGACGAAGGACTTAATGGAGAAATTTCCTATGGG
  ATCAAAATGATTTTGCCAGTGAGTGAGAAATGTATGTTTTCAATAAATCCAGACACAGGTGAAATTAGAA
  TTTATGGTGAACTGGATTTTGAAGAGAATAATGCCTATGAAATTCAGGTTAACGCCATTGATAAAGGGAT
  TCCTTCCATGGCAGGTCACAGCATGGTCCTGGTGGAAGTTCTGGACGTGAATGACAATGTCCCTGAAGTA
  ATGGTTACTTCACTGTCGCTCCCTGTGCAAGAGGATGCTCAGGTGGGTACCGTCATTGCCCTGATTAGCG
  TGTCGGATCGTGACTCTGGAGCCAATGGACAGGTCATCTGCTCACTGACACCTCATGTTCCCTTCAAGCT
  GGTGTCCACCTACAAGAATTACTACTCGTTGGTGCTGGACAGCGCCCTGGACCGCGAGAGCGTGTCGGCC
  TATGAGCTGGTGGTGACTGCGCGGGATGGGGGCTCGCCTTCGCTGTGGGCCACGGCTAGAGTGTCCGTGG
  AGGTGGCCGACGTGAACGACAATGCGCCTGCGTTCGCGCAGCCCGAGTACACAGTGTTCGTGAAGGAGAA
  CAACCCGCCGGGCTGCCACATCTTCACGGTGTCGGCATGGGACGCGGACGCGCAGAAGAACGCGCTGGTG
  TCCTACTCGCTGGTGGAGCGGCGGGTGGGCGAGCACGCACTGTCGAGCTACGTGTCGGTGCACGCGGAGA
  GCGGCAAGGTGTACGCGCTGCAGCCGCTAGACCACGAGGAGCTGGAGCTGCTGCAGTTCCAGGTGAGCGC
  GCGCGACGCCGGCGTGCCGCCTCTGGGCAGCAACGTGACGCTGCAGGTGTTCGTGCTGGACGAGAACGAC
  AACGCGCCGGCACTGCTGGCGACTCCGGCTGGCAGCGCAGGAGGCGCAGTTAGCGAGTTGGTACCGCGGT
  CGGTGGGTGCGGGCCACGTGGTGGCGAAAGTGCGCGCGGTGGACGCTGACTCCGGCTATAACGCTTGGCT
  GTCCTACGAGTTGCAACCGGCGGCGGTCGGCGCGCACATCCCGTTCCACGTGGGGCTGTACACTGGCGAG
  ATCAGCACGACACGCATCCTGGATGAGGCGGACGCTCCGCGCCACCGCCTGCTGGTGCTGGTGAAGGACC
  ACGGTGAGCCCGCGCTGACGTCCACGGCCACGGTGCTGGTGTCGCTGGTGGAGAACGGCCAGGCCCCAAA
  GACGTCGTCGCGGGCCTCAGTGGGCGCTGTGGATCCCGAAGCGGCTCTGGTGGATATTAACGTGTACCTC
  ATCATCGCCATCTGTGCGGTGTCCAGCCTGCTGGTGCTCACGCTGCTGCTGTACACTGCGCTGCGTTGCT
  CAGCGCCGCCCACCGTGAGCCGGTGCGCGCCGGGCAAGCCCACGCTGGTGTGCTCCAGCGCCGTGGGGAG
  TTGGTCTTACTCGCAGCAGAGGAGGCAGAGGGTGTGCTCTGCAGAGAGCCCGCCCAAGACGGACCTCATG
  GCCTTCAGCCCAAGCCTTCAGCTGTCTCGAGAAGATTGTTTAAATCCTCCCAGTGAAGTAAGTTATTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_031864
• ORF Size: 2379 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_031864.2, NP_114070.1
• RefSeq Size: 2588
• RefSeq ORF: 2379
• Locus ID: 56137
• Protein Families: Transmembrane
• Gene Summary: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) utilizes the large, first exon then continues into the downstream intron 1 sequence before terminating. This one-exon transcript encodes a shorter isoform (2).