TPCN1 (NM_017901) Human Untagged Clone

CAT#: SC314764

TPCN1 (untagged)-Human two pore segment channel 1 (TPCN1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TPCN1
• Synonyms: TPC1
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_017901, the custom clone sequence may differ by one or more nucleotides
  ATGGCTGTGAGTTTGGATGACGACGTGCCGCTCATCCTGACCTTGGATGAGGGTGGCAGT
  GCCCCACTGGCTCCCTCCAACGGCCTGGGCCAAGAAGAGCTACCTAGCAAAAATGGCGGC
  AGCTATGCCATCCACGACTCCCAGGCCCCCAGTCTCAGCTCTGGGGGTGAGAGTTCCCCC
  TCCAGCCCCGCACACAACTGGGAGATGAATTACCAAGAGGCAGCAATCTACCTCCAGGAA
  GGCGAGAACAACGACAAGTTCTTCACCCACCCCAAGGATGCCAAGGCGCTGGCGGCCTAC
  CTCTTTGCACACAATCACCTCTTCTACCTGATGGAGCTGGCCACGGCCCTGCTGCTGCTG
  CTGCTCTCCCTGTGCGAGGCCCCCGCCGTCCCCGCACTCCGGCTTGGCATCTATGTCCAC
  GCCACCCTGGAGCTGTTTGCCCTGATGGTGGTAGTGTTTGAACTCTGCATGAAGTTACGC
  TGGCTGGGCCTCCACACCTTCATCCGGCACAAGCGGACCATGGTCAAGACCTCGGTGCTG
  GTGGTGCAGTTTGTCGAGGCCATCGTGGTGTTGGTACGGCAGATGTCCCATGTGCGGGTG
  ACCCGAGCACTGCGCTGCATTTTCCTGGTGGACTGTCGGTATTGCGGTGGCGTCCGGCGC
  AACCTGCGGCAGATCTTCCAGTCCCTGCCGCCCTTCATGGACATCCTCCTGCTGCTGCTG
  TTCTTCATGATCATCTTTGCCATCCTCGGTTTCTACTTGTTCTCCCCTAACCCTTCAGAC
  CCCTACTTCAGCACCCTGGAGAACAGCATCGTCAGTCTGTTTGTCCTTCTGACCACAGCC
  AATTTCCCAGATGTGATGATGCCCTCCTACTCCCGGAACCCCTGGTCCTGCGTCTTCTTC
  ATCGTGTACCTCTCCATCGAGCTGTATTTCATCATGAACCTGCTTCTGGCTGTGGTGTTC
  GACACCTTCAATGACATTGAGAAACGCAAGTTCAAGTCTTTGCTACTGCACAAGCGAACC
  GCTATCCAGCATGCCTACCGCCTGCTCATCAGCCAGAGGAGGCCTGCCGGCATCTCCTAC
  AGGCAGTTTGAAGGCCTCATGCGCTTCTACAAGCCCCGGATGAGTGCCAGGGAGCGCTAT
  CTTACCTTCAAGGCCCTGAATCAGAACAACACACCCCTGCTCAGCCTAAAGGACTTTTAC
  GATATCTACGAAGTTGCTGCTTTGAAGTGGAAGGCCAAGAAAAACAGAGAGCACTGGTTT
  GATGAGCTTCCCAGGACGGCGCTCCTCATCTTCAAAGGTATTAATATCCTTGTGAAGTCC
  AAGGCCTTCCAGTATTTCATGTACTTGGTGGTGGCAGTCAACGGGGTCTGGATCCTCGTG
  GAGACATTTATGCTGAAAGGTGGGAACTTCTTCTCCAAGCACGTGCCCTGGAGTTACCTC
  GTCTTTCTAACTATCTATGGGGTGGAGCTGTTCCTGAAGGTTGCCGGCCTGGGCCCTGTG
  GAGTACTTGTCTTCCGGATGGAACTTGTTTGACTTCTCCGTGACAGTGTTCGCCTTCCTG
  GGACTGCTGGCGCTGGCCCTCAACATGGAGCCCTTCTATTTCATCGTGGTCCTGCGCCCC
  CTCCAGCTGCTGAGGTTGTTTAAGTTGAAGGAGCGCTACCGCAACGTGCTGGACACCATG
  TTCGAGCTGCTGCCCCGGATGGCCAGCCTGGGCCTCACCCTGCTCATCTTTTACTACTCC
  TTCGCCATCGTGGGCATGGAGTTCTTCTGCGGGATCGTCTTCCCCAACTGCTGCAACACG
  AGTACAGTGGCAGATGCCTACCGCTGGCGCAACCACACCGTGGGCAACAGGACCGTGGTG
  GAGGAAGGCTACTATTATCTCAATAATTTTGACAACATCCTCAACAGCTTTGTGACCCTG
  TTTGAGCTCACAGTTGTCAACAACTGGTACATCATCATGGAAGGCGTCACCTCTCAGACC
  TCCCACTGGAGCCGCCTCTACTTCATGACCTTTTACATTGTGACCATGGTGGTGATGACG
  ATCATTGTCGCCTTTATCCTCGAGGCCTTCGTCTTCCGAATGAACTACAGCCGCAAGAAC
  CAGGACTCGGAAGTTGATGGTGGCATCACCCTTGAGAAGGAAATCTCCAAAGAAGAGCTG
  GTTGCCGTCCTGGAGCTCTACCGGGAGGCACGGGGGGCCTCCTCGGATGTCACCAGGCTG
  CTGGAGACCCTCTCCCAGATGGAGAGATACCAGCAACATTCCATGGTGTTTCTGGGACGG
  CGATCAAGGACCAAGAGCGACCTGAGCCTGAAGATGTACCAGGAGGAGATCCAGGAGTGG
  TATGAGGAGCATGCCAGGGAGCAAGAGCAGCAGCGACAACTCAGCAGCAGTGCAGCCCCC
  GCCGCCCAGCAGCCCCCAGGCAGCCGCCAGCGCTCCCAGACCGTTACC
  
• Restriction Sites: Please inquire
• ACCN: NM_017901
• ORF Size: 2451 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_017901.3, NP_060371.2
• RefSeq Size: 2810
• RefSeq ORF: 2451
• Locus ID: 53373
• Protein Families: Druggable Genome, Ion Channels: Other, Transmembrane
• Gene Summary: Voltage-gated Ca(2+) and Na+ channels have 4 homologous domains, each containing 6 transmembrane segments, S1 to S6. TPCN1 is similar to these channels, but it has only 2 domains containing S1 to S6 (Ishibashi et al., 2000 [PubMed 10753632]). [supplied by OMIM, Mar 2008]
  Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and uses a downstream start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus compared to isoform 1.