CTIP1 (BCL11A) (NM_022893) Human Untagged Clone

CAT#: SC314796

BCL11A (untagged)-Human B-cell CLL/lymphoma 11A (zinc finger protein) (BCL11A), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: BCL11A
• Synonyms: BCL11A-L; BCL11a-M; BCL11A-S; BCL11A-XL; CTIP1; DILOS; EVI9; HBFQTL5; ZNF856
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_022893 edited
  ATGTCTCGCCGCAAGCAAGGCAAACCCCAGCACTTAAGCAAACGGGAATTCTCGCCCGAG
  CCTCTTGAAGCCATTCTTACAGATGATGAACCAGACCACGGCCCGTTGGGAGCTCCAGAA
  GGGGATCATGACCTCCTCACCTGTGGGCAGTGCCAGATGAACTTCCCATTGGGGGACATT
  CTTATTTTTATCGAGCACAAACGGAAACAATGCAATGGCAGCCTCTGCTTAGAAAAAGCT
  GTGGATAAGCCACCTTCCCCTTCACCAATCGAGATGAAAAAAGCATCCAATCCCGTGGAG
  GTTGGCATCCAGGTCACGCCAGAGGATGACGATTGTTTATCAACGTCATCTAGAGGAATT
  TGCCCCAAACAGGAACACATAGCAGATAAACTTCTGCACTGGAGGGGCCTCTCCTCCCCT
  CGTTCTGCACATGGAGCTCTAATCCCCACGCCTGGGATGAGTGCAGAATATGCCCCGCAG
  GGTATTTGTAAAGATGAGCCCAGCAGCTACACATGTACAACTTGCAAACAGCCATTCACC
  AGTGCATGGTTTCTCTTGCAACACGCACAGAACACTCATGGATTAAGAATCTACTTAGAA
  AGCGAACACGGAAGTCCCCTGACCCCGCGGGTTGGTATCCCTTCAGGACTAGGTGCAGAA
  TGTCCTTCCCAGCCACCTCTCCATGGGATTCATATTGCAGACAATAACCCCTTTAACCTG
  CTAAGAATACCAGGATCAGTATCGAGAGAGGCTTCCGGCCTGGCAGAAGGGCGCTTTCCA
  CCCACTCCCCCCCTGTTTAGTCCACCACCGAGACATCACTTGGACCCCCACCGCATAGAG
  CGCCTGGGGGCGGAAGAGATGGCCCTGGCCACCCATCACCCGAGTGCCTTTGACAGGGTG
  CTGCGGTTGAATCCAATGGCTATGGAGCCTCCCGCCATGGATTTCTCTAGGAGACTTAGA
  GAGCTGGCAGGGAACACGTCTAGCCCACCGCTGTCCCCAGGCCGGCCCAGCCCTATGCAA
  AGGTTACTGCAACCATTCCAGCCAGGTAGCAAGCCGCCCTTCCTGGCGACGCCCCCCCTC
  CCTCCTCTGCAATCCGCCCCTCCTCCCTCCCAGCCCCCGGTCAAGTCCAAGTCATGCGAG
  TTCTGCGGCAAGACGTTCAAATTTCAGAGCAACCTGGTGGTGCACCGGCGCAGCCACACG
  GGCGAGAAGCCCTACAAGTGCAACCTGTGCGACCACGCGTGCACCCAGGCCAGCAAGCTG
  AAGCGCCACATGAAGACGCACATGCACAAATCGTCCCCCATGACGGTCAAGTCCGACGAC
  GGTCTCTCCACCGCCAGCTCCCCGGAACCCGGCACCAGCGACTTGGTGGGCAGCGCCAGC
  AGCGCGCTCAAGTCCGTGGTGGCCAAGTTCAAGAGCGAGAACGACCCCAACCTGATCCCG
  GAGAACGGGGACGAGGAGGAAGAGGAGGACGACGAGGAAGAGGAAGAAGAGGAGGAAGAG
  GAGGAGGAGGAGCTGACGGAGAGCGAGAGGGTGGACTACGGCTTCGGGCTGAGCCTGGAG
  GCGGCGCGCCACCACGAGAACAGCTCGCGGGGCGCGGTCGTGGGCGTGGGCGACGAGAGC
  CGCGCCCTGCCCGACGTCATGCAGGGCATGGTGCTCAGCTCCATGCAGCACTTCAGCGAG
  GCCTTCCACCAGGTCCTGGGCGAGAAGCATAAGCGCGGCCACCTGGCCGAGGCCGAGGGC
  CACAGGGACACTTGCGACGAAGACTCGGTGGCCGGCGAGTCGGACCGCATAGACGATGGC
  ACTGTTAATGGCCGCGGCTGCTCCCCGGGCGAGTCGGCCTCGGGGGGCCTGTCCAAAAAG
  CTGCTGCTGGGCAGCCCCAGCTCGCTGAGCCCCTTCTCTAAGCGCATCAAGCTCGAGAAG
  GAGTTCGACCTGCCCCCGGCCGCGATGCCCAACACGGAGAACGTGTACTCGCAGTGGCTC
  GCCGGCTACGCGGCCTCCAGGCAGCTCAAAGATCCCTTCCTTAGCTTCGGAGACTCCAGA
  CAATCGCCTTTTGCCTCCTCGTCGGAGCACTCCTCGGAGAACGGGAGCTTGCGCTTCTCC
  ACACCGCCCGGGGAGCTGGACGGAGGGATCTCGGGGCGCAGCGGCACGGGAAGTGGAGGG
  AGCACGCCCCATATTAGTGGTCCGGGCCCGGGCAGGCCCAGCTCAAAAGAGGGCAGACGC
  AGCGACACTTGTGAGTACTGTGGGAAAGTCTTCAAGAACTGTAGCAATCTCACTGTCCAC
  AGGAGAAGCCACACGGGCGAAAGGCCTTATAAATGCGAGCTGTGCAACTATGCCTGTGCC
  CAGAGTAGCAAGCTCACCAGGCACATGAAAACGCATGGCCAGGTGGGGAAGGACGTTTAC
  AAATGTGAAATTTGTAAGATGCCTTTTAGCGTGTACAGTACCCTGGAGAAACACATGAAA
  AAATGGCACAGTGATCGAGTGTTGAATAATGATATAAAAACTGAATAG
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_022893 unedited
  GTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCCGCAGCCCACCATGTC
  TCGCCGCAAGCAAGGCAAACCCCAGCACTTAAGCAAACGGGAATTCTCGCCCGAGCCTCT
  TGAAGCCATTCTTACAGATGATGAACCAGACCACGGCCCGTTGGGAGCTCCAGAAGGGGA
  TCATGACCTCCTCACCTGTGGGCAGTGCCAGATGAACTTCCCATTGGGGGACATTCTTAT
  TTTTATCGAGCACAAACGGAAACAATGCAATGGCAGCCTCTGCTTAGAAAAAGCTGTGGA
  TAAGCCACCTTCCCCTTCACCAATCGAGATGAAAAAAGCATCCAATCCCGTGGAGGTTGG
  CATCCAGGTCACGCCAGAGGATGACGATTGTTTATCAACGTCATCTAGAGGAATTTGCCC
  CAAACAGGAACACATAGCAGATAAACTTCTGCACTGGAGGGGCCTCTCCTCCCCTCGTTC
  TGCACATGGAGCTCTAATCCCCACGCCTGGGATGAGTGCAGAATATGCCCCGCAGGGTAT
  TTGTAAAGATGAGCCCAGCAGCTACACATGTACAACTTGCAAACAGCCATTCACCAGTGC
  ATGGTTTCTCTTGCAACACGCACAGAACACTCATGGATTAAGAATCTACTTAGAAAGCGA
  ACACGGAAGTCCCCTGACCCCGCGGGTTGGTATCCCTTCAGGACTAGGTGCAGAATGTCC
  TTCCCAGCCACCTCTCCATGGGATTCATATTGCAGACAATAACCCCTTTAACCTGCTAAG
  AATACCAGGATCAGTATCGAGAGAAGCTTCCGGCCTGNCAGAAGGCGCTTTCCACCCACT
  CCCCCCTGTTTATCCACCACGAGACATACTGGGACCCCACCGCATANACGCCTGGGGCNG
  NAGAGATGCCCTGGCCACCATAACCCGATGCTTGNAAGGTG
  
  3' Read Nucleotide Sequence

  >Forward primer walk for NM_022893 unedited
  GGCGCCACGGCACGGNAGTGGAGGAGCAGCCCCATATTATGGTCCGGGCCCGGGCAGGCC
  CAGCTCAAAAGAGGCAGACGCAGCGACACTTGTGAGTACTGTGGGAAAGTCTTCAAGAAC
  TGTAGCAATCTCACTGTCCACAGGAGAAGCCACACGGGCGAAAGGCCTTATAAATGCGAG
  CTGTGCAACTATGCCTGTGCCCAGAGTAGCAAGCTCACCAGGCACATGAAAACGCATGGC
  CAGGTGGGGAAGGACGTTTACAAATGTGAAATTTGTAAGATGCCTTTTAGCGTGTACAGT
  ACCCTGGAGAAACACATGAAAAAATGGCACAGTGATCGAGTGTTGAATAATGATATAAAA
  ACTGAATAGAGGTTCTTCACACACCCCCATTCGGCGTAGTACCCAGAGAGCTCAAGATGT
  GTGGCAGTTTTCGGATGGAAGCTCGAGAGCCCTTAAGTTCTGAGAAAATTTGAAGCCCCC
  AGGGGTGNGGGTGGACGCGTGCCGCCCAGTCGACGTCAGCGTGGTCTGTCATCCTGCTAG
  TTTGTGATGTTTTCTGACAGTAGCCTCCAAGAAGCCGTTGTGCGAAGACAGAGTCCTGCA
  GAGTCCTTCCAGCCTANGCCTGCAGCGCCATTTTATTTATATTTTTTTATAAAAAGTAAA
  AACAAAAAAACAGACCCACATTGGGACAGTGAATCAGTCCCATAGAGAGGGCCCGTGGAC
  CATCGCTGTCATGAGTGATGCCCTGGCCCTTCTGAAACCAGCCAACCTAATTACCTGTAT
  TGTGGGAATGCGCATGAGTCCCCCACCCCTTGTTTCTATACATTCTATGGTGGCTTTTAA
  AAAGTGTGCTTAACATTGCACAATAATGTTTGGAGCTTTAAAAAAAAAAAAAAANAAAAA
  ANNNNNNNAAAAAAAAAAAANNNNNNAA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_022893
• ORF Size: 2508 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.

Reference Data

• RefSeq: NM_022893.2, NP_075044.2
• RefSeq Size: 5963
• RefSeq ORF: 2508
• Locus ID: 53335
• Domains: zf-C2H2
• Protein Families: Transcription Factors
• Gene Summary: This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) is also known as B-cell lymphoma/leukaemia 11A extra long form (BCL11A-XL). It encodes the longest isoform (1).