OSMR (NM_003999) Human Untagged Clone

CAT#: SC315027

OSMR (untagged)-Human oncostatin M receptor (OSMR), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: OSMR
• Synonyms: IL-31R-beta; IL-31RB; OSMRB; PLCA1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_003999 edited
  ATGGCTCTATTTGCAGTCTTTCAGACAACATTCTTCTTAACATTGCTGTCCTTGAGGACT
  TACCAGAGTGAAGTCTTGGCTGAACGTTTACCATTGACTCCTGTATCACTTAAAGTTTCC
  ACCAATTCTACGCGTCAGAGTTTGCACTTACAATGGACTGTCCACAACCTTCCTTATCAT
  CAGGAATTGAAAATGGTATTTCAGATCCAGATCAGTAGGATTGAAACATCCAATGTCATC
  TGGGTGGGGAATTACAGCACCACTGTGAAGTGGAACCAGGTTCTGCATTGGAGCTGGGAA
  TCTGAGCTCCCTTTGGAATGTGCCACACACTTTGTAAGAATAAAGAGTTTGGTGGACGAT
  GCCAAGTTCCCTGAGCCAAATTTCTGGAGCAACTGGAGTTCCTGGGAGGAAGTCAGTGTA
  CAAGATTCTACTGGACAGGATATATTGTTCGTTTTCCCTAAAGATAAGCTGGTGGAAGAA
  GGCACCAATGTTACCATTTGTTACGTTTCTAGGAACATTCAAAATAATGTATCCTGTTAT
  TTGGAAGGGAAACAGATTCATGGAGAACAACTTGATCCACATGTAACTGCATTCAACTTG
  AATAGTGTGCCTTTCATTAGGAATAAAGGGACAAATATCTATTGTGAGGCAAGTCAAGGA
  AATGTCAGTGAAGGCATGAAAGGCATCGTTCTTTTTGTCTCAAAAGTACTTGAGGAGCCC
  AAGGACTTTTCTTGTGAAACCGAGGACTTCAAGACTTTGCACTGTACTTGGGATCCTGGG
  ACGGACACTGCCTTGGGGTGGTCTAAACAACCTTCCCAAAGCTACACTTTATTTGAATCA
  TTTTCTGGGGAAAAGAAACTTTGTACACACAAAAACTGGTGTAATTGGCAAATAACTCAA
  GACTCACAAGAAACCTATAACTTCACACTCATAGCTGAAAATTACTTAAGGAAGAGAAGT
  GTCAATATCCTTTTTAACCTGACTCATCGAGTTTATTTAATGAATCCTTTTAGTGTCAAC
  TTTGAAAATGTAAATGCCACAAATGCCATCATGACCTGGAAGGTGCACTCCATAAGGAAT
  AATTTCACATATTTGTGTCAGATTGAACTCCATGGTGAAGGAAAAATGATGCAATACAAT
  GTTTCCATCAAGGTGAACGGTGAGTACTTCTTAAGTGAACTGGAACCTGCCACAGAGTAC
  ATGGCGCGAGTACGGTGTGCTGATGCCAGCCACTTCTGGAAATGGAGTGAATGGAGTGGT
  CAGAACTTCACCACACTTGAAGCTGCTCCCTCAGAGGCCCCTGATGTCTGGAGAATTGTG
  AGCTTGGAGCCAGGAAATCATACTGTGACCTTATTCTGGAAGCCATTATCAAAACTGCAT
  GCCAATGGAAAGATCCTGTTCTATAATGTAGTTGTAGAAAACCTAGACAAACCATCCAGT
  TCAGAGCTCCATTCCATTCCAGCACCAGCCAACAGCACAAAACTAATCCTTGACAGGTGT
  TCCTACCAAATCTGCGTCATAGCCAACAACAGTGTGGGTGCTTCTCCTGCTTCTGTAATA
  GTCATCTCTGCAGACCCCGAAAACAAAGAGGTTGAGGAAGAAAGAATTGCAGGCACAGAG
  GGTGGATTCTCTCTGTCTTGGAAACCCCAACCTGGAGATGTTATAGGCTATGTTGTGGAC
  TGGTGTGACCATACCCAGGATGTGCTCGGTGATTTCCAGTGGAAGAATGTAGGTCCCAAT
  ACCACAAGCACAGTCATTAGCACAGATGCTTTTAGGCCAGGAGTTCGATATGACTTCAGA
  ATTTATGGGTTATCTACAAAAAGGATTGCTTGTTTATTAGAGAAAAAAACAGGATACTCT
  CAGGAACTTGCTCCTTCAGACAACCCTCACGTGCTGGTGGATACATTGACATCCCACTCC
  TTCACTCTGAGTTGGAAAGATTACTCTACTGAATCTCAACCTGGTTTTATACAAGGGTAC
  CATGTCTATCTGAAATCCAAGGCGAGGCAGTGCCACCCACGATTTGAAAAGGCAGTTCTT
  TCAGATGGTTCAGAATGTTGCAAATACAAAATTGACAACCCGGAAGAAAAGGCATTGATT
  GTGGACAACCTAAAGCCAGAATCCTTCTATGAGTTTTTCATCACTCCATTCACTAGTGCT
  GGTGAAGGCCCCAGTGCTACGTTCACGAAGGTCACGACTCCGGATGAACACTCCTCGATG
  CTGATTCATATCCTACTGCCCATGGTTTTCTGCGTCTTGCTCATCATGGTCATGTGCTAC
  TTGAAAAGTCAGTGGATCAAGGAGACCTGTTATCCTGACATCCCTGACCCTTACAAGAGC
  AGCATCCTGTCATTAATAAAATTCAAGGAGAACCCTCACCTAATAATAATGAATGTCAGT
  GACTGTATCCCAGATGCTATTGAAGTTGTAAGCAAGCCAGAAGGGACAAAGATACAGTTC
  CTAGGCACTAGGAAGTCACTCACAGAAACCGAGTTGACTAAGCCTAACTACCTTTATCTC
  CTTCCAACAGAAAAGAATCACTCTGGCCCTGGCCCCTGCATCTGTTTTGAGAACTTGACC
  TATAACCAGGCAGCTTCTGACTCTGGCTCTTGTGGCCATGTTCCAGTATCCCCAAAAGCC
  CCAAGTATGCTGGGACTAATGACCTCACCTGAAAATGTACTAAAGGCACTAGAAAAAAAC
  TACATGAACTCCCTGGGAGAAATCCCAGCTGGAGAAACAAGTTTGAATTATGTGTCCCAG
  TTGGCTTCACCCATGTTTGGAGACAAGGACAGTCTCCCAACAAACCCAGTAGAGGCACCA
  CACTGTTCAGAGTATAAAATGCAAATGGCAGTCTCCCTGCGTCTTGCCTTGCCTCCCCCG
  ACCGAGAATAGCAGCCTCTCCTCAATTACCCTTTTAGATCCAGGTGAACACTACTGCTAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003999 unedited
  GCGGTCAGGATTTGNATACGATTCCTCATAGGCGGCCGCGATTCGGCACCAGGCGCTTGC
  CCCGCAGCTGATTCATAGCCCCGGCCCGGGCCGCCTCTGCACGTCCGCCCCGGAGCCCGC
  ACCCGCGCCCCACGCGCCGCCGAGGACTCGGCCCGGCTCGTGGAGCCCTTCGCCCGCGGC
  GTGAGTACCCCCGACCCGCCCGTCCCCGCTCTGCTCGCGCCCTGCCGCTGCGCCGCCCTC
  GGTGGCTTTTCCGACGGGCGAGCCCCGTGCTGTGCGGGAAAGAATCCGACAACTTCGCAG
  CCCATCCCGGCTGGACGCGACCGGGAGTGCAGCAGCCCGTTCCCCTCCTCGGTGCCGCCT
  CTGCCCAGCGTTTGCTTGGCTGGGCTACCACCTGCGCTCGGACGGCGCTCGGAGGGTCCT
  CGCCCCCGGCCTGCCTACCTGAAAACCAGAACTGATGGCTCTATTTGCAGTCTTTCAGAC
  AACATTCTTCTTAACATTGCTGTCCTTGAGGACTTACCAGAGTGAAGTCTTGGCTGAACG
  TTTACCATTGACTCCTGTATCACTTAAAGTTTCCACCAATTCTACGCGTCAGAGTTTGCA
  CTTACAATGGACTGTCCACAACCTTCCTTATCATCAGGAATTGAAAATGGTATTTCAGAT
  CCAGATCAGTAGGATTGAAACATCCAATGTCATCTGGGTGGGGAATTACAGCACCACTGT
  GAAGTGGAACCAGGTTCTGCATTGGAGCTGGGAATCTGAGCTCCCTTTGGAATGTGCCAC
  ACACTTTGTAAGAATAAAGAGTTNGGTGGACGATGCCCAGTTNCCTGAGCCAAATTTCTG
  GNAGCACTGGAGNTNCTGGGAGGAAGTCAGTGTACAAGATCTACTGGACAGGATATATGN
  NTCGTNTCCTAAAGAAG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003999
• ORF Size: 2940 bp
• Insert Size: 4700
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to be a perfect match to NM_003999.1.

Reference Data

• RefSeq: NM_003999.1, NP_003990.1
• RefSeq Size: 4171
• RefSeq ORF: 2940
• Locus ID: 9180
• Domains: FN3
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway
• Gene Summary: This gene encodes a member of the type I cytokine receptor family. The encoded protein heterodimerizes with interleukin 6 signal transducer to form the type II oncostatin M receptor and with interleukin 31 receptor A to form the interleukin 31 receptor, and thus transduces oncostatin M and interleukin 31 induced signaling events. Mutations in this gene have been associated with familial primary localized cutaneous amyloidosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]