MMP16 (NM_005941) Human Untagged Clone

CAT#: SC316625

MMP16 (untagged)-Human matrix metallopeptidase 16 (membrane-inserted) (MMP16)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MMP16
• Synonyms: C8orf57; MMP-X2; MT-MMP2; MT-MMP3; MT3-MMP
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_005941 edited
  GAATTCGGCACGAGGCTGCAGGCTCCTTACCCACCCGGAGGACTTTTTTTTTGAAAGGAA
  ACGAGGGAGGGAGGGAGAGGGAGAGAGGGAGAAAACGAAGGGGAGCTCGTCCATCCATTG
  AAGCACAGTTCACTATGATCTTACTCACATTCAGCACTGGAAGACGGTTGGATTTCGTGC
  ATCATTCGGGGGTGTTTTTCTTGCAAACCTTGCTTTGGATTTTATGTGCTACAGTCTGCG
  GAACGGAGCAGTATTTCAATGTGGAGGTTTGGTTACAAAAGTACGGCTACCTTCCACCGA
  CTGACCCCAGAATGTCAGTGCTGCGCTCTGCAGAGACCATGCAGTCTGCCCTAGCTGCCA
  TGCAGCAGTTCTATGGCATTAACATGACAGGAAAAGTGGACAGAAACACAATTGACTGGA
  TGAAGAAGCCCCGATGCGGTGTACCTGACCAGACAAGAGGTAGCTCCAAATTTCATATTC
  GTCGAAAGCGATATGCATTGACAGGACAGAAATGGCAGCACAAGCACATCACTTACAGTA
  TAAAGAACGTAACTCCAAAAGTAGGAGACCCTGAGACTCGTAAAGCTATTCGCCGTGCCT
  TTGATGTGTGGCAGAATGTAACTCCTCTGACATTTGAAGAAGTTCCCTACAGTGAATTAG
  AAAATGGCAAACGTGATGTGGATATAACCATTATTTTTGCATCTGGTTTCCATGGGGACA
  GCTCTCCCTTTGATGGAGAGGGAGGATTTTTGGCACATGCCTACTTCCCTGGACCAGGAA
  TTGGAGGAGATACCCATTTTGACTCAGATGAGCCATGGACACTAGGAAATCCTAATCATG
  ATGGAAATGACTTATTTCTTGTAGCAGTCCATGAACTGGGACATGCTCTGGGATTGGAGC
  ATTCCAATGACCCCACTGCCATCATGGCTCCATTTTACCAGTACATGGAAACAGACAACT
  TCAAACTACCTAATGATGATTTACAGGGCATCCAGAAGATATATGGTCCACCTGACAAGA
  TTCCTCCACCTACAAGACCTCTACCGACAGTGCCCCCACACCGCTCTATTCCTCCGGCTG
  ACCCAAGGAAAAATGACAGGCCAAAACCTCCTCGGCCTCCAACCGGCAGACCCTCCTATC
  CCGGAGCCAAACCCAACATCTGTGATGGGAACTTTAACACTCTAGCTATTCTTCGTCGTG
  AGATGTTTGTTTTCAAGGACCAGTGGTTTTGGCGAGTGAGAAACAACAGGGTGATGGATG
  GATACCCAATGCAAATTACTTACTTCTGGCGGGGCTTGCCTCCTAGTATCGATGCAGTTT
  ATGAAAATAGCGACGGGAATTTTGTGTTCTTTAAAGGTAACAAATATTGGGTGTTCAAGG
  ATACAACTCTTCAACCTGGTTACCCTCATGACTTGATAACCCTTGGAAGTGGAATTCCCC
  CTCATGGTATTGATTCAGCCATTTGGTGGGAGGACGTCGGGAAAACCTATTTCTTCAAGG
  GAGACAGATATTGGAGATATAGTGAAGAAATGAAAACAATGGACCCTGGCTATCCCAAGC
  CAATCACAGTCTGGAAAGGGATCCCTGAATCTCCTCAGGGAGCATTTGTACACAAAGAAA
  ATGGCTTTACGTATTTCTACAAAGGAAAGGAGTATTGGAAATTCAACAACCAGATACTCA
  AGGTAGAACCTGGATATCCAAGATCCATCCTCAAGGATTTTATGGGCTGTGATGGACCAA
  CAGACAGAGTTAAAGAAGGACACAGCCCACCAGATGATGTAGACATTGTCATCAAACTGG
  ACAACACAGCCAGCACTGTGAAAGCCATAGCTATTGTCATTCCCTGCATCTTGGCCTTAT
  GCCTCCTTGTATTGGTTTACACTGTGTTCCAGTTCAAGAGGAAAGGAACACCCCGCCACA
  TACTGTACTGTAAACGCTCTATGCAAGAGTGGGTGTGATGTAGGGTTTTTTCTTCTTTCT
  TTCTTTTGCACGAGTTTGTGGTAACTTGAGATTCAAGACAAGAGCTGTTATGCTGTTTCC
  TAGCTAGGAGCAGGCTTGTGGCAGCCTGATTCGGGGCTGACCTTTCAAACCCAGAGGGTT
  GCTGGTCCTGCACATGAGTGGAAATACACTCATGGGGAAGCTTCCATGATGCACAGTAXX
  XXXXXXXXXXXXXXXXXXXXXXXXXXCTAAGTCTTCTTTTCTTTTTTTTTAGGCATACTG
  AATTTCTGTTTTAAAATCCATTGCATGAAAATTCAATTTGCCTTGGTATATGCAGTTAGC
  ATTGCCATTTTAAAAATGAATTAAAACGGTGACTCTGAAGTTGCATGAATATCCTCCAGT
  GCATTACCTATTGCATGTCCACCATAGTTCTCAAAGGGTTAGTGTGGCTTCTGGCATTTA
  GCCGTCCATTTGATCACTGACAGAGCCAAGAGACCACCAAAGCATTTCATTGTTGAGTGT
  AATTTGTCCTAACAGCAGTATTGTCATTTTCATGTGACCTGCAGAGCAGGTTTGTATCAA
  TATTTTTTTCCTAGAGAAAAGTCAGCAACTGACAGACCTCTTTATTGATTTTTAGGAGCT
  GCTTCTTGCAGTGAAAGGCTTTACAGCCACTGGGCTGTGAACTTATTAGAGATGGTCAGA
  ATGAATGCACCCCATGAGTCAGACATTGGCTTTGTGTGAAAGCCAGCTTTGAGGGGATTA
  GCTTTTGAAACAATGAACAGCTTGCCTTGAACTTGATTATTGATCTATTGACTGTCATTA
  ACAACAACTTAAACATTGTCTTCTGTGAAAATTTTCCTTGAAGAGTCCTGTTCTATGTCT
  TTGCCCTTTGACCTTTAACTTGCAAACTGGCACAAACTGAAGGAAATCTGGTGTTGCTTC
  TCCATTGGATTAGTTGTTCTCTAAAACCTAGTAAGCATGAGCTGTTTCCTTAGAGTGGAG
  AGAGTGGTGATGGCAGATCTGCAGATGGACACTTTGCTCTTTACATGCACACTCTGAAAA
  TGCCCTATAGGTAGAAGTGAATTTTAATTTCATTTTAATATAATTTCAAGTCTAAATTCA
  TCATTTTAGTACAAATTACAAAAAAAAAAAAAAAAAACTCGAC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005941 unedited
  AGAATTTTGTAATACGACTCACTATAGGGCGGCCGCGAAATTCGCACGAGGCTGCAGGCT
  CCTTACCCACCCGGNAGACTTTTTTTTTGAAAGGAAACGAGGGAGGGAGGGAGAGGGAGA
  GAGGGAGAAAACGAAGGGGAGCTCGTCCATCCATTGAAGCACAGTTCACTATGATCTTAC
  TCACATTCAGCACTGGAAGACGGTTGGATTTCGTGCATCATTCGGGGGTGTTTTTCTTGC
  AAACCTTGCTTTGGATTTTATGTGCTACAGTCTGCGGAACGGAGCAGTATTTCAATGTGG
  AGGTTTGGTTACAAAAGTACGGCTACCTTCCACCGACTGACCCCAGAATGTCAGTGCTGC
  GCTCTGCAGAGACCATGCAGTCTGCCCTAGCTGCCATGCAGCAGTTCTATGGCATTAACA
  TGACAGGAAAAGTGGACAGAAACACAATTGACTGGATGAAGAAGCCCCGATGCGGTGTAC
  CTGACCAGACAAGAGGTAGCTCCAAATTTCATATTCGTCGAAAGCGATATGCATTGACAG
  GACAGAAATGGCAGCACAAGCACATCACTTACAGTATAAAGAACGTAACTCCAAAAGTAG
  GAGACCCTGAGACTCGTAAAGCTATTCGCCGTGCCTTTGATGTGTGGCAGAATGTAACTC
  CTCTGACATTTGAAGAAGTTCCCTACAGTGAATTAGAAAATGGCAAACGTGATGTGGATA
  TAACCATTATTTTTGCATCTGGTTTCCATGGGGACAGCTCTCCCTTTGATGGAGAGGGGA
  GATTTTTGGCACATGCCTACTTCCCTGGACCAGGAATTGGANGAGATACCCATTNTGACT
  CAGATGAGCCATGGACACTANGAAATNNCTATCATGATGGNAATGANCTATTTCTTGTAG
  CAGTCCATGAACTGGGGACATGCTCTGGGATGGNAGCATTNCATGACCCCACTGNCTCAT
  GGCTNCATTTTACCAGTCATGGAAACAGACACTTCAACTACCTATGAG
  
  3' Read Nucleotide Sequence

  >OriGene 3' genomic read for NM_005941 unedited
  GTACCGCGGCCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTGTAATTTGTACTAA
  AATGATGAATTTAGACTTGAAATTATATTAAAATGAAATTAAAATTCACTTCTACCTATA
  GGGCATTTTCAGAGTGTGCATGTAAAGAGCAAAGTGTCCATCTGCAGATCTGCCATCACC
  ACTCTCTCCACTCTAAGGAAACAGCTCATGCTTACTAGGTTTTAGAGAACAACTAATCCA
  ATGGAGAAGCAACACCAGATTTCCTTCAGTTTGTGCCAGTTTGCAAGTTAAAGGTCAAAG
  GGCAAAGACATAGAACAGGACTCTTCAAGGAAAATTTTCACAGAAGACAATGTTTAAGTT
  GTTGTTAATGACAGTCAATAGATCAATAATCAAGTTCAAGGCAAGCTGTTCATTGTTTCA
  AAAGCTAATCCCCTCAAAGCTGGCTTTCACACAAAGCCAATGTCTGACTCATGGGGTGCA
  TTCATTCTGACCATCTCTAATAAGTTCACAGCCCAGTGGCTGTAAAGCCTTTCACTGCAA
  GAAGCAGCTCCTAAAAATCAATAAAGAGGTCTGTCAGTTGCTGACTTTTCTCTAGGAAAA
  AAATATTGATACAAACCTGCTCTGCAGGTCACATGAAAATGAACATACTGCTGTTAGGAC
  AAATTACACTCAACAATGAAATGCTTTGGTGGTCTCTTGGCTCTGTCAGTGATCAAATGG
  ACGGCTAAATGCCAGAAGCACCACTTACCCTTTGAGAACTATGGTGGACATGCAATANGT
  AATGCACTGGAGGAAATCATGCAACTCCGAGTCCCCGTTTAAATCTTTTTAAATGGCATG
  CTACTGCTATACCAAGCAATGAATTTCTGCATGGATTTAAACGGAATCATTTGCTAAAAA
  AAAAAAAAAACTAGCTTTTCGTTTTCAAAAAATTCGATTTTGAAACTAATAATACTTTTA
  ATTGCCGAAATTTGGCAGTACTCTN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_005941
• Insert Size: 4110 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_005941.2, NP_005932.2
• RefSeq Size: 2589 bp
• RefSeq ORF: 1824 bp
• Locus ID: 4325
• Cytogenetics: 8q21.3
• Protein Families: Druggable Genome, Protease, Secreted Protein, Transmembrane
• Gene Summary: 'Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The encoded protein activates MMP2 by cleavage. This gene was once referred to as MT-MMP2, but was renamed as MT-MMP3 or MMP16. [provided by RefSeq, Oct 2010]'