ASH2L (NM_001105214) Human Untagged Clone

CAT#: SC317115

ASH2L (untagged)-Human ash2 (absent, small, or homeotic)-like (Drosophila) (ASH2L), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ASH2L
• Synonyms: ASH2; ASH2L1; ASH2L2; Bre2
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001105214, the custom clone sequence may differ by one or more nucleotides
  ATGGATACTCAGGCGGGCTCCGTGGATGAAGAGAATGGCCGACAGTTGGGTGAGGTAGAG
  CTGCAATGTGGGATTTGTACAAAATGGTTCACGGCTGACACATTTGGCATAGATACCTCA
  TCCTGTCTACCTTTCATGACCAACTACAGTTTTCATTGCAACGTCTGCCATCACAGTGGG
  AATACCTATTTCCTCCGGAAGCAAGCAAACTTGAAGGAAATGTGCCTTAGTGCTTTGGCC
  AACCTGACATGGCAGTCCCGAACACAGGATGAACATCCGAAGACAATGTTCTCCAAAGAT
  AAGGATATTATACCATTTATTGATAAATACTGGGAGTGCATGACAACCAGACAGAGACCT
  GGGAAAATGACTTGGCCAAATAACATTGTTAAAACAATGAGTAAAGAAAGAGATGTATTC
  TTGGTAAAGGAACACCCAGATCCAGGCAGTAAAGATCCAGAAGAAGATTACCCCAAATTT
  GGACTTTTGGATCAGGACCTTAGTAACATTGGTCCTGCTTATGACAACCAAAAACAGAGC
  AGTGCTGTGTCTACTAGTGGGAATTTAAATGGGGGAATTGCAGCAGGAAGCAGCGGAAAA
  GGACGAGGAGCCAAGCGCAAACAGCAGGATGGAGGGACCACAGGGACCACCAAGAAGGCC
  CGGAGTGACCCTTTGTTTTCTGCTCAGCGCCTTCCCCCTCATGGCTACCCATTGGAACAC
  CCGTTTAACAAAGATGGCTATCGGTATATTCTAGCTGAGCCTGATCCGCACGCCCCTGAC
  CCCGAGAAGCTGGAACTTGACTGCTGGGCAGGAAAACCTATTCCTGGAGACCTCTACAGA
  GCCTGCTTGTATGAACGGGTTTTGTTAGCCCTACATGATCGAGCTCCCCAGTTAAAGATC
  TCAGATGACCGGCTGACTGTGGTTGGAGAGAAGGGCTACTCTATGGTGAGGGCCTCTCAT
  GGAGTACGGAAAGGTGCCTGGTATTTTGAAATCACTGTGGATGAGATGCCACCAGATACC
  GCTGCCAGACTGGGTTGGTCCCAGCCCCTAGGAAACCTTCAAGCTCCTTTAGGTTATGAT
  AAATTTAGCTATTCTTGGCGGAGCAAAAAGGGAACCAAGTTCCACCAGTCCATTGGCAAA
  CACTACTCTTCTGGCTATGGACAGGGAGACGTCCTGGGATTTTATATTAATCTTCCTGAA
  GACACAGAGACAGCCAAGTCATTGCCAGACACATACAAAGATAAGGCTTTGATAAAATTC
  AAGAGTTATTTGTATTTTGAGGAAAAAGACTTTGTGGATAAAGCAGAGAAGAGCCTGAAG
  CAGACTCCCCATAGTGAGATAATATTTTATAAAAATGGTGTCAATCAAGGTGTGGCTTAC
  AAAGATATTTTTGAGGGGGTTTACTTCCCAGCCATCTCACTGTACAAGAGCTGCACGGTT
  TCCATTAACTTTGGACCATGCTTCAAGTATCCTCCGAAGGATCTCACTTACCGCCCTATG
  AGTGACATGGGCTGGGGCGCCGTGGTAGAGCACACCCTGGCTGACGTCTTGTATCACGTG
  GAGACAGAAGTGGATGGGAGGCGCAGTCCCCCATGGGAACCC
  
• Restriction Sites: Please inquire
• ACCN: NM_001105214
• ORF Size: 1605 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001105214.1, NP_001098684.1
• RefSeq Size: 2662
• RefSeq ORF: 1605
• Locus ID: 9070
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis. [UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at a downstream, in-frame start codon, compared to variant 1. The encoded isoform (b) has a shorter N-terminus, compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.