Claudin 23 (CLDN23) (NM_194284) Human Untagged Clone

CAT#: SC317428

CLDN23 (untagged)-Human claudin 23 (CLDN23)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CLDN23
• Synonyms: CLDNL; hCG1646163
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_194284 edited
  ATGCGGACGCCGGTGGTGATGACGCTGGGCATGGTGTTGGCGCCCTGCGGGCTCCTGCTC
  AACCTGACCGGCACCCTGGCGCCCGGCTGGCGGCTGGTGAAGGGCTTCCTGAACCAGCCA
  GTGGACGTGGAGTTGTACCAGGGCCTGTGGGACATGTGTCGCGAGCAGAGCAGCCGCGAG
  CGCGAGTGCGGCCAGACGGACCAGTGGGGCTACTTCGAGGCCCAGCCCGTGCTGGTGGCG
  CGGGCACTCATGGTCACCTCGCTGGCCGCCACGGTCCTGGGGCTTCTGCTGGCGTCGCTG
  GGCGTGCGCTGCTGGCAGGACGAGCCCAACTTCGTGCTGGCAGGGCTCTCGGGCGTCGTG
  CTCTTCGTCGCTGGCCTCCTCGGCCTCATCCCGGTGTCCTGGTACAACCACTTCTTGGGG
  GACCGCGACGTGCTGCCCGCCCCGGCCAGCCCGGTCACGGTGCAGGTCAGCTACAGCCTG
  GTCCTGGGCTACCTGGGCAGCTGCCTCCTGCTGCTGGGCGGCTTCTCGCTGGCGCTCAGC
  TTCGCGCCCTGGTGCGACGAGCGTTGTCGCCGCCGCCGCAAGGGACCCTCCGCCGGGCCT
  CGCCGCAGCAGCGTCAGCACCATCCAAGTGGAGTGGCCCGAGCCCGACCTGGCGCCCGCC
  ATCAAGTACTACAGCGACGGCCAGCACCGACCGCCGCCTGCCCAGCACCGCAAGCCCAAG
  CCCAAGCCCAAGGTCGGCTTCCCCATGCCGCGGCCGCGGCCCAAGGCCTACACCAACTCG
  GTGGACGTCCTCGACGGGGAGGGGTGGGAGTCCCAGGACGCTCCCTCGTGCAGCACCCAC
  CCCTGCGACAGCTCGCTGCCCTGCGACTCCGACCTCTAG
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for XM_059895 unedited
  TTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGTCCAGGCCAGGCG
  TGGCCCAGCCGCCCGGCTGCAAGGTGGGGTGTCCCCGCCGCTCGGATCCCCATCTCGCCT
  GCCGCGGGCGAGGTGGCCCCGCCGCTTCCTGCGCTCACCTCGGGTCCCTCCCTCCCGGGC
  CAGGTTTGGCCACGGCGGCCGCCCCTGGGCGCCCGCGCCCGGACCCGCGGTTTCGGTCAG
  ACCCGCCCGCGGGCTGGTTTCGATTAGGGCCTGTAGGAGGGCGGAGCGGCCGGGACGCCA
  GGAGGGAACTAGCCTAAGTGGGGACGGTCCCCGTGCAGGAGACAAAGAGCGTCCCTGGAG
  CGATCAGGGCTCAGGAGCCCGACCCGGAGCCCGGGGCGTCCGCGCTGACTTCGGGTCCCC
  GGAGCCTGGGGCACGGCAGGGAGAAGACGACGGCGGAGAAGGCGACAGCGGAGAAGGAAG
  GCAGGCTGCAGGGGCGCCGTCGGCGCAGCGGGCCGGGATGCGGACGCCGGTGGTGATGAC
  GCTGGGCATGGTGTTGGCGCCCTGCGGGCTCCTGCTCAACCTGACCGGCACCCTGGCGCC
  CGGCTGGCGGCTGGTGAAGGGCTTCCTGAACCAGCCAGTGGACGTGGAGTTGTACCAGGG
  CCCTGTGGGACATGTGTCGCGAGCAGAGCAGCCGCGAGCGCGAGTGCGGCCAGACGGACC
  AGTGGNGCTACTTCGAGGCCCAGCCCGTGCTGGTGGCGCGGGCACTCATGGTCACCTCGC
  TGGCCGNCACGGTCCTGGGGCTTCTGCTGGCGTCGCTGGGCGTGCGCTGCTGGGCAGACN
  AGCCCCACTTCGTGCTGGCAAGGCTCTNCGGCGTCGTGCTCTTCGTCGCTGGCCTCCTCG
  GCTCATNCCGGTGTCCTGGACCACCCTC
  
• Restriction Sites: Please inquire
• ACCN: NM_194284
• ORF Size: 879 bp
• Insert Size: 2200
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_194284.2, NP_919260.2
• RefSeq Size: 1972
• RefSeq ORF: 879
• Locus ID: 137075
• Protein Pathways: Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Tight junction
• Gene Summary: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is expressed in germinal center B-cells, placenta and stomach as well as in colon tumor. This gene is down-regulated in intestinal type gastric cancer. [provided by RefSeq, Aug 2010]