P2X6 (P2RX6) (NM_005446) Human Untagged Clone

CAT#: SC317723

P2RX6 (untagged)-Human purinergic receptor P2X, ligand-gated ion channel, 6 (P2RX6), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: P2RX6
• Synonyms: P2RXL1; P2X6; P2XM
• Vector: PCMV6-Neo
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_005446 edited
  ATGTGCCCGCAGCTAGCAGGAGCTGGCAGCATGGGCTCCCCAGGGGCTACGACAGGCTGG
  GGGCTTCTGGATTATAAGACGGAGAAGTATGTGATGACCAGGAACTGGCGGGTGGGCGCC
  CTGCAGAGGCTGCTGCAGTTTGGGATCGTGGTCTATGTGGTAGGGTGGGCTCTCCTCGCC
  AAAAAAGGCTACCAGGAGCGGGACCTGGAACCCCAGTTTTCCATCATCACCAAACTCAAA
  GGGGTTTCCGTCACTCAGATCAAGGAGCTTGGAAACCGGCTGTGGGATGTGGCCGACTTC
  GTGAAGCCACCTCAGGGAGAGAACGTGTTCTTCTTGGTGACCAACTTCCTTGTGACGCCA
  GCCCAAGTTCAGGGCAGATGCCCAGAGCACCCGTCCGTCCCACTGGCTAACTGCTGGGTC
  GACGAGGACTGCCCCGAAGGGGAGGGAGGCACACACAGCCACGGTGTAAAAACAGGCCAG
  TGTGTGGTGTTCAATGGGACCCACAGGACCTGTGAGATCTGGAGTTGGTGCCCAGTGGAG
  AGTGGCGTTGTGCCCTCGAGGCCCCTGCTGGCCCAGGCCCAGAACTTCACACTGTTCATC
  AAAAACACAGTCACCTTCAGCAAGTTCAACTTCTCTAAGTCCAATGCCTTGGAGACCTGG
  GACCCCACCTATTTTAAGCACTGCCGCTATGAACCACAATTCAGCCCCTACTGTCCCGTG
  TTCCGCATTGGGGACCTCGTGGCCAAGGCTGGAGGGACCTTCGAGGACCTGGCGTTGCTG
  GGTGGCTCTGTAGGCATCAGAGTTCACTGGGATTGTGACCTGGACACCGGGGACTCTGGC
  TGCTGGCCTCACTACTCCTTCCAGCTGCAGGAGAAGAGCTACAACTTCAGGACAGCCACT
  CACTGGTGGGAGCAACCGGGTGTGGAGGCCCGCACCCTGCTCAAGCTCTATGGAATCCGC
  TTCGACATCCTCGTCACCGGGCAGGCAGGGAAGTTCGGGCTCATCCCCACGGCCGTCACA
  CTGGGCACCGGGGCAGCTTGGCTGGGCGTGGTCACCTTTTTCTGTGACCTGCTACTGCTG
  TATGTGGATAGAGAAGCCCATTTCTACTGGAGGACAAAGTATGAGGAGGCCAAGGCCCCG
  AAAGCAACCGCCAACTCTGTGTGGAGGGAGCTGGCCCTTGCATCCCAAGCCCGACTGGCC
  GAGTGCCTCAGACGGAGCTCAGCACCTGCACCCACGGCCACTGCTGCTGGGAGTCAGACA
  CAGACACCAGGATGGCCCTGTCCAAGTTCTGACACCCACTTGCCAACCCATTCCGGGAGC
  CTGTAG
  
• Restriction Sites: Please inquire
• ACCN: NM_005446
• ORF Size: 1326 bp
• Insert Size: 1300
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_005446.3, NP_005437.2
• RefSeq Size: 2754
• RefSeq ORF: 1326
• Locus ID: 9127
• Protein Families: Druggable Genome, Ion Channels: ATP Receptors, Transmembrane
• Protein Pathways: Calcium signaling pathway, Neuroactive ligand-receptor interaction
• Gene Summary: The protein encoded by this gene belongs to the family of P2X receptors, which are ATP-gated ion channels and mediate rapid and selective permeability to cations. This gene is predominantly expressed in skeletal muscle, and regulated by p53. The encoded protein is associated with VE-cadherin at the adherens junctions of human umbilical vein endothelial cells. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 22, has been identified. [provided by RefSeq, Apr 2009]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).