Bestrophin 2 (BEST2) (NM_017682) Human Untagged Clone

CAT#: SC317855

BEST2 (untagged)-Human bestrophin 2 (BEST2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: BEST2
• Synonyms: VMD2L1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_017682, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGACCGTCACCTACACAGCCCGAGTGGCGAACGCCCGCTTCGGTGGCTTCTCCCAGCTGCTGCTACTGT
  GGCGTGGGAGCATCTACAAACTCCTGTGGCGAGAGCTGCTCTGCTTCCTTGGGTTCTACATGGCGCTGAG
  TGCTGCCTACCGCTTTGTGCTGACCGAAGGGCAGAAGCGCTACTTCGAGAAGCTTGTGATTTATTGTGAC
  CAGTATGCCAGCCTCATCCCTGTCTCCTTCGTGCTTGGCTTTTATGTGACGCTGGTGGTGAACCGCTGGT
  GGAGCCAGTACCTATGCATGCCGCTGCCCGACGCGCTCATGTGCGTGGTGGCGGGCACCGTGCACGGACG
  CGACGACCGCGGCCGCCTCTACCGGCGCACACTCATGCGCTACGCAGGGCTCTCGGCCGTGCTCATCCTG
  CGCTCCGTCAGCACCGCGGTGTTCAAGCGCTTCCCCACCATAGACCACGTGGTGGAGGCTGGGTTTATGA
  CCCGCGAGGAGCGCAAGAAGTTTGAAAACCTGAACTCATCCTACAACAAGTACTGGGTGCCCTGCGTCTG
  GTTCTCCAACCTGGCGGCACAGGCCCGACGCGAGGGCCGCATCCGCGACAACAGCGCCCTTAAGCTGCTG
  CTCGAGGAGCTGAATGTTTTTCGGGGCAAATGTGGAATGCTCTTTCACTATGACTGGATTAGCGTACCCC
  TCGTGTACACGCAGGTGGTGACCATCGCACTGTACAGCTACTTCCTGGCTTGCCTCATTGGTCGCCAGTT
  CCTGGACCCGGCTCAGGGTTACAAAGACCACGACCTAGACCTGTGTGTGCCCATCTTCACCCTCTTGCAG
  TTCTTCTTCTACGCCGGCTGGCTCAAGGTAGCTGAGCAGCTCATCAACCCCTTCGGAGAGGACGATGATG
  ACTTTGAGACCAACTTTCTGATCGATAGAAACTTCCAGGTGTCCATGCTGGCAGTGGACGAGATGTATGA
  TGACCTGGCTGTGCTGGAGAAGGACTTGTACTGGGATGCAGCCGAGGCTCGCGCCCCATACACAGCGGCT
  ACTGTCTTCCAGCTGCGGCAGCCTTCCTTCCAGGGCTCCACCTTTGACATCACGCTGGCCAAAGAAGACA
  TGCAGTTCCAGCGGCTGGACGGCTTGGATGGACCGATGGGAGAGGCGCCCGGCGACTTCCTGCAGCGCCT
  CCTGCCGGCGGGCGCGGGCATGGTCGCGGGAGGCCCGCTGGGCCGGCGCCTGTCCTTTCTACTCCGCAAG
  AACAGCTGCGTGTCGGAGGCGTCTACTGGGGCCAGCTGCTCATGCGCGGTTGTCCCCGAAGGCGCGGCCC
  CGGAGTGCAGCTGCGGGGACCCGCTGCTCGACCCCGGCCTGCCGGAGCCCGAGGCCCCGCCCCCTGCGGG
  TCCCGAACCGCTTACCCTCATCCCTGGGCCTGTCGAGCCCTTCAGCATCGTGACCATGCCCGGGCCCCGG
  GGTCCGGCGCCACCCTGGCTGCCCAGCCCTATTGGCGAGGAGGAGGAGAATCTGGCCTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_017682
• ORF Size: 1530 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_017682.2, NP_060152.2
• RefSeq Size: 1924
• RefSeq ORF: 1530
• Locus ID: 54831
• Protein Families: Transmembrane
• Gene Summary: This gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3' ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in one of the family members (bestrophin 1) is associated with vitelliform macular dystrophy. The bestrophin 2 gene is mainly expressed in the retinal pigment epithelium and colon. [provided by RefSeq, Jul 2008]