EYA4 (NM_172103) Human Untagged Clone

CAT#: SC318057

EYA4 (untagged)-Human eyes absent homolog 4 (Drosophila) (EYA4), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: EYA4
• Synonyms: CMD1J; DFNA10
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_172103 edited
  GGGAAAAGCCGGGGAGTGACGACTGCGGCGGCTGGGCGCGCTCTCTCATTTTCTTTTCTT
  CTCCTTTCCCCCCTGTCGCAGTCCGGAGTTTTGGCTCCTCTCCTTTCCTCCTCCCCCTCG
  GAGCCGGCTTCTCCCTCCGCCCCGCTTCTCCCCCGCTTGTGTACGCTATTTGTTGTGGGG
  TGGCCGAAGGGGATGTCCTGTTTTCACCAGAGGCACAGCGCGAAGGGGAAACTTCGACAC
  TGGAAGGAACGAGAATAAATACTTAATTACGGACGCACTGAACCGCGGCTGGGACAGACA
  CTTCGGGAACCCGAGGCGGACCGGGCGACGAGATAGTCATTTTTACTTGAAGGAAGCTGC
  TTCTACTTGGGAGTGGCAGGAGAAGTGAGAAAACCACATGGAAGACTCCCAGGATTTAAA
  TGAACAATCAGTAAAGAAAACGTGCACAGAATCAGATGTTTCACAATCTCAGAATTCCAG
  GTCTATGGAAATGCAGGACCTAGCAAGTCCTCATACTCTTGTTGGAGGTGGTGATACTCC
  AGGTAGCTCCAAACTGGAAAAATCTAATCTCAGCAGCACATCAGTTACTACAAATGGGAC
  AGGAGTGTCTCTTCTTGCAGTCAAAACAGAGCCCTTGAACAGCAGTGAAACCACAGCCAC
  GACTGGAGATGGAGCGCTTGACACTTTTACTGGGTCAGTAATTACAAGTAGTGGCTACAG
  CCCCAGATCAGCACATCAGTATTCCCCACAGCTGTATCCTTCCAAGCCCTATCCACACAT
  TCTTTCTACACCAGCAGCTCAAACAATGTCTGCCTATGCAGGCCAGACTCAGTATTCGGG
  GATGCAGCAGCCAGCCGTCTACACAGCCTACTCACAGACAGGACAGCCCTACAGCTTGCC
  CACTTACGATTTGGGTGTGATGTTGCCAGCCATCAAGACAGAGAGTGGACTTTCCCAAAC
  TCAGTCCCCATTACAGAGTGGCTGCCTCAGTTACAGCCCAGGGTTCTCTACCCCACAGCC
  AGGCCAGACACCTTATTCTTACCAAATGCCAGGTTCTAGTTTTGCACCATCATCTACTAT
  TTATGCAAATAATTCAGTTTCCAATTCAACAAATTTCAGTGGTTCACAACAGGATTATCC
  ATCCTATACAGCCTTTGGCCAAAACCAGTATGCACAGTATTATTCAGCATCAACGTATGG
  AGCGTATATGACATCGAATAACACAGCCGATGGCACACCCTCTTCAACCTCTACTTATCA
  GTTGCAGGAATCTCTCCCAGGACTGACTAACCAACCAGGAGAGTTCGATACCATGCAGAG
  TCCCTCCACACCCATCAAAGATCTTGATGAGAGAACCTGTAGGAGTTCTGGGTCAAAGTC
  CAGAGGAAGAGGCCGGAAAAATAATCCCTCCCCGCCTCCTGATAGTGACCTGGAGCGTGT
  GTTTGTCTGGGATTTGGATGAAACCATCATTGTTTTTCACTCACTGCTCACCGGGTCTTA
  TGCACAGAAGTATGGCAAGGATCCCCCCATGGCTGTAACCCTTGGACTCCGCATGGAAGA
  AATGATTTTTAATCTTGCTGATACTCATTTGTTTTTTAATGATTTAGAGGAGTGTGATCA
  AGTTCATATAGATGATGTTTCCTCTGATGATAATGGGCAGGACTTAAGTACCTACAGTTT
  TGCAACTGATGGCTTCCATGCAGCTGCAAGTAGTGCAAACCTTTGTTTGCCAACAGGTGT
  AAGAGGAGGGGTTGACTGGATGAGGAAGTTGGCTTTTCGTTACAGAAGAGTAAAAGAATT
  ATATAACACCTACAAGAACAACGTTGGAGGACTCCTTGGCCCTGCCAAGAGGGATGCCTG
  GCTACAGTTAAGGGCAGAGATTGAAGGTCTGACAGATTCCTGGCTAACAAATGCACTTAA
  GTCTTTATCAATTATTAGCACTAGGAGTAACTGCATAAATGTCTTGGTAACGACAACTCA
  ACTGATCCCAGCACTTGCGAAGGTTCTACTCTATAGTTTAGGAGGTGCTTTCCCCATTGA
  GAATATTTACAGTGCAACTAAAATAGGAAAAGAAAGTTGCTTTGAACGAATAATGCAAAG
  GTTTGGCAGAAAAGTAGTGTATGTTGTAATTGGGGATGGTGTAGAAGAAGAACAGGCAGC
  AAAAAAGCACAACATGCCCTTCTGGAGGATATCCAGTCACTCAGACCTCCTGGCTCTCCA
  CCAAGCACTGGAATTAGAGTATTTGTAACTGTGTTCTTTAGCCGGAGATCTATTTTTTAT
  ATTTCAAGTACACTGAATTTTTATGTGTGATTCAATGCCTCTGGCTCTACACATATAAAT
  TGTCTTAATGGATGAAATCATATTTGGAATAAAAATTCCAGAATGAAGAATTCAGATTGC
  TGAATGGAGTTAAACTTTAGTGCTACAGAAAAGAAACTCTATGGTCTTATATTTACAACA
  CTTTAATGGGTTTTTTAAAAATCTGTGGAGGTTGCTGGTACACACCAAATGAGTCCAAAC
  TGGAATGAGCAGCTTTAGCAAAGAACTCTTACCTGGCAAAGCAGCAACACACATGCTCCG
  TCTGACAAGGTGGTCAACAACATTCCTCAAAATGGGAGATCTTCTCAGCCCTGAGGTTTG
  AATCTGACTTTAGCCTACCTAACCCAGAAAATCTGAATTGGAATGCACTCAGACTGTATA
  AGGACAGTCCTATTTAGACATGTAATTTGTGTAAATTATTGATGAAAATAATTTACTGTG
  ACTTTATTAGCAGCTGACTTTCAAAGTGGATGCAATTTTTCTTTCTTTTGTTGGGGAGGG
  GAATGGGAGGGGAAATGGGAATATAATATTGTCTCTTTTTTAAGTTTGGCAAACAGAATG
  TTCATACTGATGTGTTGTGCCTTAAAGACAAGACAGCATTTGTGTGTTACAATGTAACTT
  TGGTTAAAATCTCTGTAGATAATGAAAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for SC321470 unedited
  GACATTGTATACGACTCCTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAG
  GAGATCTGCCGCCGCGATCGCGGCGCGCCAGATCTCAAGCTTAACTAGTTAGCGGACCGA
  CGCGTTAAGCGGCCGCGAATTCAGATCCACAAGTTTGTACAAAAAAGCAGGCTTGTAAAA
  CGACGGCCAGTAACTATAACGGTCCTAAGGTAGCGAGGCCTGGGTGGCGAATTCGGCACG
  AGGGGGAAAAGCCGGGGAGTGACGACTGCGGCGGCTGGGCGCGCTCTCTCATTTTCTTTT
  CTTCTCCTTTCCCCCCTGTCGCAGTCCGGAGTTTTGGCTCCTCTCCTTTCCTCCTCCCCC
  TCGGAGCCGGCTTCTCCCTCCGCCCCGCTTCTCCCCCGCTTGTGTACGCTATTTGTTGTG
  GGGTGGCCGAAGGGGATGTCCTGTTTTCACCAGAGGCACAGCGCGAAGGGGAAACTTCGA
  CACTGGAAGGAACGAGAATAAATACTTAATTACGGACGCACTGAACCGCGGCTGGGACAG
  ACACTTCGGGAACCCGAGGCGGACCGGGCGACGAGATAGTCATTTTTACTTGAAGGAAGC
  TGCTTCTACTTGGGAGTGGCAGGAGAAGTGAGAAAACCACATGGAAGACTCCCAGGATTT
  AAATGAACAATCAGTAAAGAAAACGTGCACAGAATCAGATGTTTCACAATCTCAGAATTT
  CCAGGTCTATGGAAATGCAGACCTAGCAAGTCCTCATACTCTTGTTGGAGGTGGTGATAC
  TCCAGGTAGCTCCAAACTGGAAAAATCTAATCTCAGCAGCACATCAGTTACTACAATGGG
  AACAGAGTGTCTCTCTGCAGTCAAAACAGAGCCCTGACAGCAGTGAAACACAGCCACGAC
  TGAGAATGGAGCGCCTTGACACCTTTACTGGTCAGTAATTACAAGTAATG
• Restriction Sites: Please inquire
• ACCN: NM_172103
• ORF Size: 1851 bp
• Insert Size: 3000
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to be a perfect match to NM_172103.2.

Reference Data

• RefSeq: NM_172103.2, NP_742101.2
• RefSeq Size: 5031
• RefSeq ORF: 1851
• Locus ID: 2070
• Protein Families: Druggable Genome, Phosphatase, Transcription Factors
• Gene Summary: This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator through its protein phosphatase activity, and it may be important for eye development, and for continued function of the mature organ of Corti. Mutations in this gene are associated with postlingual, progressive, autosomal dominant hearing loss at the deafness, autosomal dominant non-syndromic sensorineural 10 locus. The encoded protein is also a putative oncogene that mediates DNA repair, apoptosis, and innate immunity following DNA damage, cellular damage, and viral attack. Defects in this gene are also associated with dilated cardiomyopathy 1J. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]
  Transcript Variant: This variant (2) lacks an in-frame segment of the 5' coding region, compared to variant 1. The resulting isoform (b) is shorter than isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The extent of this transcript is supported by transcript alignments.