EYA4 (NM_172103) Human Untagged Clone

CAT#: SC109201

EYA4 (untagged)-Human eyes absent homolog 4 (Drosophila) (EYA4), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: EYA4
• Synonyms: CMD1J; DFNA10
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_172103, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGAAGACTCCCAGGATTTAAATGAACAATCAGTAAAGAAAACGTGCACAGAATCAGATGTTTCACAAT
  CTCAGAATTCCAGGTCTATGGAAATGCAGGACCTAGCAAGTCCTCATACTCTTGTTGGAGGTGGTGATAC
  TCCAGGTAGCTCCAAACTGGAAAAATCTAATCTCAGCAGCACATCAGTTACTACAAATGGGACAGGAGTG
  TCTCTTCTTGCAGTCAAAACAGAGCCCTTGAACAGCAGTGAAACCACAGCCACGACTGGAGATGGAGCGC
  TTGACACTTTTACTGGGTCAGTAATTACAAGTAGTGGCTACAGCCCCAGATCAGCACATCAGTATTCCCC
  ACAGCTGTATCCTTCCAAGCCCTATCCACACATTCTTTCTACACCAGCAGCTCAAACAATGTCTGCCTAT
  GCAGGCCAGACTCAGTATTCGGGGATGCAGCAGCCAGCCGTCTACACAGCCTACTCACAGACAGGACAGC
  CCTACAGCTTGCCCACTTACGATTTGGGTGTGATGTTGCCAGCCATCAAGACAGAGAGTGGACTTTCCCA
  AACTCAGTCCCCATTACAGAGTGGCTGCCTCAGTTACAGCCCAGGGTTCTCTACCCCACAGCCAGGCCAG
  ACACCTTATTCTTACCAAATGCCAGGTTCTAGTTTTGCACCATCATCTACTATTTATGCAAATAATTCAG
  TTTCCAATTCAACGAATTTCAGTGGTTCACAACAGGATTATCCATCCTATACAGCCTTTGGCCAAAACCA
  GTATGCACAGTATTATTCAGCATCAACGTATGGAGCGTATATGACATCGAATAACACAGCCGATGGCACA
  CCCTCTTCAACCTCTACTTATCAGTTGCAGGAATCTCTCCCAGGACTGACTAACCAACCAGGAGAGTTCG
  ATACCATGCAGAGTCCCTCCACACCCATCAAAGATCTTGATGAGAGAACCTGTAGGAGTTCTGGGTCAAA
  GTCCAGAGGAAGAGGCCGGAAAAATAATCCCTCCCCGCCTCCTGATAGTGACCTGGAGCGTGTGTTTGTC
  TGGGATTTGGATGAAACCATCATTGTTTTTCACTCACTGCTCACCGGGTCTTATGCACAGAAGTATGGCA
  AGGATCCCCCCATGGCTGTAACCCTTGGACTCCGCATGGAAGAAATGATTTTTAATCTTGCTGATACTCA
  TTTGTTTTTTAATGATTTAGAGGAGTGTGATCAAGTTCATATAGATGATGTTTCCTCTGATGATAATGGG
  CAGGACTTAAGTACCTACAGTTTTGCAACTGATGGCTTCCATGCAGCTGCAAGTAGTGCAAACCTTTGTT
  TGCCAACAGGTGTAAGAGGAGGGGTTGACTGGATGAGGAAGTTGGCTTTTCGTTACAGAAGAGTAAAAGA
  ATTATATAACACCTACAAGAACAACGTTGGAGGACTCCTTGGCCCTGCCAAGAGGGATGCCTGGCTACAG
  TTAAGGGCAGAGATTGAAGGTCTGACAGATTCCTGGCTAACAAATGCACTTAAGTCTTTATCAATTATTA
  GCACTAGGAGTAACTGCATAAATGTCTTGGTAACGACAACTCAACTGATCCCAGCACTTGCGAAGGTTCT
  ACTCTATAGTTTAGGAGGTGCTTTCCCCATTGAGAATATTTACAGTGCAACTAAAATAGGAAAAGAAAGT
  TGCTTTGAACGAATAATGCAAAGGTTTGGCAGAAAAGTAGTGTATGTTGTAATTGGGGATGGTGTAGAAG
  AAGAACAGGCAGCAAAAAAGCACAACATGCCCTTCTGGAGGATATCCAGTCACTCAGACCTCCTGGCTCT
  CCACCAAGCACTGGAATTAGAGTATTTGTAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_172103 unedited
  CGGATTTTGTATACGATCTCACTATAGGGCGGCCGCGATTCGGCACGAGGGTGGCCGAAG
  GGATGTCCTGTTTTCACCAGAGGCACAGCGCGAAGGGGAAACTTCGACACTGGAAGGAAC
  GAGAATAAATACTTAATTACGGACGCACTGAACCGCGGCTGGGACAGACACTTCGGGAAC
  CCGAGGCGGACCGGGCGACGAGATAGTCATTTTTACTTGAAGGAAGCTGCTTCTACTTGG
  GAGTGGCAGGAGAAGTGAGAAAACCACATGGAAGACTCCCAGGATTTAAATGAACAATCA
  GTAAAGAAAACGTGCACAGAATCAGATGTTTCACAATCTCAGAATTCCAGGTCTATGGAA
  ATGCAGGACCTAGCAAGTCCTCATACTCTTGTTGGAGGTGGTGATACTCCAGGTAGCTCC
  AAACTGGAAAAATCTAATCTCAGCAGCACATCAGTTACTACAAATGGGACAGGAGTGTCT
  CTTCTTGCAGTCAAAACAGAGCCCTTGAACAGCAGTGAAACCACAGCCACGACTGGAGAT
  GGAGCGCTTGACACTCTTACTGGGTCAGTAATTACAAGTAGTGGCTACAGCCCCAGATCA
  GCACATCAGTATTCCCCACAGCTGTATCCTTCCAAGCCCTATCCACACATTCTTTCTACA
  CCAGCAGCTCAAACAATGTCTGCCTATGCAGGCCAGACTCAGTATTCGGGGATGCAGCAG
  CCAGCCGTCTACACAGCCTACTCACAGACAGGACAGNCCTACAGCTTGGCCACTTACGAT
  TTGGGGTGTGATGTTGCCAGCCATCCAGACAGAGAGTGGACTTTCCAAACTCAATCCCCA
  TTACAGAGTGGGCTGCTCAGTTACAGCCCAGGGTTTTCTACCCNAAGNCAGCCAGGAAAC
  TTAATCTTACCAAATGCAGGTTCTAGTTTGACCATATT
  
  3' Read Nucleotide Sequence

  >OriGene 3' genomic read for NM_172103 unedited
  CCCCCAAATGTTAGNCCGCGGCCGCAATCTACGAGCGGGTNTTTTTTTTTTTTTTTTTTT
  TTTTTTTTTTTTTTTTTTTTTTTTTTTTAAGAGCCGACCTGGATTTTAAGGGGAATAATA
  GCCAATATTAACATTTTTTAGATAGTTTAAAATTTATTTTGGAAGTATCGTTACCAACAT
  CAACATTTGGGAAAGCAAGGGGGCATCAAAATCCTACCTGGTTAAGGGAAAGCAGGTTTT
  AATCAGGGCATCACTCCTACGGGCCTTTCAATTAAAAATAAAATGAAACCAAATGACCAA
  CTTTTTAATTTTGTTAATCTAGGAAGAAAAGAGGGTGAATTCCTTTTTGTATAAAAATAA
  TTTGAAGCCGGACTACCTAAAGTAAAAAAAAAAGGGGGGGATTATAACTTTTTTACTTGT
  TTGGGACCACCCATAACTTAAGCCCGTAGAGGCCACCTGATTTATTTCACTGGCGTAAAA
  TTGAGAGAAAGTACTTTAGCATACATTTTCAAGGGGGAAGATATTTCCCAAGGGACCCAA
  ATGAGCTTTTGTGGGGCAAAAAAACTTAGACAATACCGGGGTGTTGGGGCCTTCAAAAGA
  GATACTATAATAGTATACCGTCCATATGTGACATTAAAATTTCATGAAAGGGGGTAATTA
  GAGAAAAACTGGTAAAGGAGTCCCACTGGCGATGATAATGAAAAGAAAAAACCCTGCTTA
  CANGAACTGGCCAAACAAAGCATGAATTGNTAAATTTGGGCTGGGGACATTTTTAGAAAA
  TTTCCTATAACAATTCTGTTTTAGGGAAAGGGGTTTTTGAATTAAACATGCACAGAATTT
  TTTTAAGAGCTAGGCCAAAGACCCTTTTGTTATTATTCTTTTTCCACATAGGACCACCCC
  CCTGGGGATTGGCATTAAAGGGTTGGACCTTTAAAACAAGGATTCAGACTTGCCAAC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_172103
• ORF Size: 5628 bp
• Insert Size: 4400
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_172103.1, NP_742101.1
• RefSeq Size: 5628
• RefSeq ORF: 5628
• Locus ID: 2070
• Protein Families: Druggable Genome, Phosphatase, Transcription Factors
• Gene Summary: This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator through its protein phosphatase activity, and it may be important for eye development, and for continued function of the mature organ of Corti. Mutations in this gene are associated with postlingual, progressive, autosomal dominant hearing loss at the deafness, autosomal dominant non-syndromic sensorineural 10 locus. The encoded protein is also a putative oncogene that mediates DNA repair, apoptosis, and innate immunity following DNA damage, cellular damage, and viral attack. Defects in this gene are also associated with dilated cardiomyopathy 1J. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]
  Transcript Variant: This variant (2) lacks an in-frame segment of the 5' coding region, compared to variant 1. The resulting isoform (b) is shorter than isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The extent of this transcript is supported by transcript alignments.