SGEF (ARHGEF26) (NM_015595) Human Untagged Clone

CAT#: SC318346

ARHGEF26 (untagged)-Human Rho guanine nucleotide exchange factor (GEF) 26 (ARHGEF26)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ARHGEF26
• Synonyms: CSGEF; HMFN1864; SGEF
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_015595, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGACGGCGAGAGCGAGGTGGATTTTTCTAGCAACAGCATAACCCCTTTGTGGCGGAGGCGGTCGATTC
  CTCAGCCCCACCAGGTTCTGGGCCGGAGCAAGCCGAGGCCCCAGTCCTACCAGAGCCCCAACGGGTTACT
  AATTACGGATTTCCCGGTGGAGGACGGAGGGACGCTCCTCGCAGCGCAGATTCCCGCCCAGGTGCCCACC
  GCCTCGGACAGCAGGACGGTACATAGGAGCCCCCTGCTTCTGGGCGCCCAGCGGAGAGCGGTGGCCAATG
  GTGGGACGGCATCCCCGGAGTACAGGGCTGCCTCTCCTCGACTTCGACGGCCCAAGTCACCCAAGCTCCC
  CAAAGCGGTGCCTGGCGGCTCCCCGAAATCCCCAGCAAATGGCGCGGTGACCTTGCCTGCGCCGCCGCCG
  CCGCCGGTTCTGCGCCCCCCGCGGACTCCTAACGCGCCCGCCCCCTGCACCCCCGAGGAGGACCTTACTG
  GGTTGACTGCCAGCCCGGTGCCTTCGCCCACTGCAAATGGCCTTGCCGCTAATAACGACTCTCCTGGGTC
  AGGTTCGCAGTCCGGCCGGAAGGCAAAGGACCCCGAACGGGGGCTCTTTCCTGGGCCCCAGAAAAGTTCT
  TCGGAACAAAAACTCCCCCTCCAAAGGCTGCCCTCCCAGGAGAACGAGCTCCTCGAGAATCCTTCCGTGG
  TTTTGAGTACAAACAGCCCCGCCGCCCTCAAAGTGGGGAAGCAGCAGATCATTCCGAAGAGTCTGGCCTC
  GGAAATTAAAATAAGTAAATCCAACAATCAAAATGTGGAGCCCCACAAGAGACTCCTCAAGGTGCGCAGC
  ATGGTGGAGGGCCTAGGAGGACCCCTGGGTCACGCAGGGGAGGAGAGTGAGGTCGATAACGACGTGGATA
  GCCCAGGGTCTCTGCGGAGAGGCTTGCGGTCCACGTCTTATCGCAGGGCAGTGGTCAGTGGCTTTGATTT
  TGACAGTCCTACCAGCTCGAAGAAGAAGAACAGAATGTCCCAGCCTGTTCTGAAAGTGGTGATGGAAGAC
  AAGGAGAAGTTTTCCAGTCTGGGAAGGATAAAGAAAAAAATGCTGAAAGGACAAGGAACATTTGATGGGG
  AAGAAAATGCTGTCCTGTATCAAAACTACAAGGAAAAGGCCCTTGACATTGATTCTGATGAAGAGTCAGA
  GCCCAAAGAACAGAAGTCAGATGAAAAAATTGTGATTCACCATAAGCCATTGAGATCCACATGGAGCCAA
  CTCTCTGCGGTGAAAAGAAAGGGATTATCTCAGACAGTAAGCCAGGAGGAAAGAAAGAGACAAGAGGCTA
  TCTTTGAAGTCATATCCTCTGAACATTCATATTTACTCAGCTTGGAGATCTTGATACGAATGTTTAAAAA
  TTCTAAAGAACTGAGTGATACAATGACTAAAACCGAGAGGCACCATCTTTTCTCCAATATTACAGATGTC
  TGTGAGGCAAGCAAAAAGTTCTTTATAGAGTTGGAAGCAAGACATCAGAATAATATCTTCATAGATGACA
  TAAGTGACATTGTGGAAAAACACACAGCATCCACATTTGACCCATATGTGAAATACTGCACAAATGAAGT
  CTACCAACAACGAACACTACAAAAATTGTTAGCTACCAATCCATCCTTTAAGGAAGTATTGTCAAGGATT
  GAGTCCCATGAAGACTGTAGGAACTTACCCATGATCTCTTTTCTCATTCTCCCCATGCAGAGGGTGACCC
  GCCTTCCCCTGCTGATGGATACTATCTGTCAAAAAACACCTAAGGACTCTCCGAAGTATGAAGTCTGCAA
  AAGAGCCTTGAAGGAAGTTAGCAAGTTGGTTCGACTATGCAATGAGGGCGCCCGGAAGATGGAAAGGACT
  GAGATGATGTACACAATTAACTCCCAGCTGGAATTTAAAATTAAGCCTTTTCCTTTAGTCTCCTCTTCCC
  GGTGGTTGGTAAAAAGAGGTGAATTGACAGCCTATGTTGAAGACACTGTGCTTTTCTCAAGAAGGACATC
  CAAACAGCAAGTCTACTTCTTTCTCTTTAACGATGTGCTCATTATCACCAAGAAGAAGAGTGAAGAAAGT
  TACAACGTCAATGATTATTCCTTAAGAGATCAGCTATTGGTGGAATCTTGTGACAATGAAGAGCTTAATT
  CTTCTCCAGGGAAGAACAGCTCCACAATGCTCTATTCAAGACAGAGCTCTGCCAGTCACCTCTTTACTCT
  GACAGTCCTTAGTAACCACGCGAATGAGAAAGTGGAGATGCTACTAGGAGCTGAGACGCAGAGCGAGCGA
  GCCCGCTGGATAACTGCCCTGGGACACAGCAGCGGGAAGCCGCCTGCAGACCGAACCTCACTGACCCAGG
  TGGAAATCGTTAGGTCATTTACTGCTAAGCAGCCAGATGAACTCTCCCTGCAGGTGGCTGACGTCGTCCT
  CATCTATCAACGTGTCAGCGATGGCTGGTATGAGGGGGAACGACTACGAGATGGAGAAAGAGGCTGGTTT
  CCTATGGAATGTGCCAAGGAGATAACATGTCAAGCTACAATTGATAAGAATGTGGAGAGAATGGGACGCT
  TGCTAGGACTGGAGACCAACGTGTAG
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_015595
• ORF Size: 2616 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_015595.3, NP_056410.3
• RefSeq Size: 5181
• RefSeq ORF: 2616
• Locus ID: 26084
• Domains: RhoGEF, SH3, PH
• Gene Summary: This gene encodes a member of the Rho-guanine nucleotide exchange factor (Rho-GEF) family. These proteins regulate Rho GTPases by catalyzing the exchange of GDP for GTP. The encoded protein specifically activates RhoG and plays a role in the promotion of macropinocytosis. Underexpression of the encoded protein may be a predictive marker of chemoresistant disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]
  Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.