PMVK (NM_006556) Human Untagged Clone

CAT#: SC319138

PMVK (untagged)-Human phosphomevalonate kinase (PMVK)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PMVK
• Synonyms: HUMPMKI; PMK; PMKA; PMKASE; POROK1
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_006556.3 GAAGGTTCTGGGCGGGGCTGGACTGTTCTAAGTGAGTTCGGGTGGGGGAGCTTCACGAGG
  GGAGGCTGCTCTGTGAAGGAACCGCCTTTCTCTCCGCGTGTCTCACCCTTTTCTCCCCAT
  ATCTGTTTGGACATGAGCTGAGGGCACGGTCGCGGGCGGTCAGCCCTGTTCGCAGCTACG
  GCGAGGAGGGGCGCGATTGTTCCTTGTTGCCGCTCCGCTTAGTGGCCGCGTCCATTCCGC
  GCGGTGTCCCGATTTTAGGGGTAGGGAGAAGTGTCAGCTTCAGGCATCGCGAGGCGTGGC
  GGCCCCATGGCCCCGCTGGGAGGCGCCCCGCGGCTGGTACTGCTGTTCAGCGGCAAGAGG
  AAATCCGGGAAGGACTTCGTGACCGAGGCGCTGCAGAGCAGACTTGGAGCTGATGTCTGT
  GCTGTCCTCCGGCTCTCTGGTCCACTCAAGGAACAGTATGCTCAGGAGCATGGCTTGAAC
  TTCCAGAGACTCCTGGACACCAGCACCTACAAGGAGGCCTTTCGGAAGGACATGATCCGC
  TGGGGAGAGGAGAAACGCCAGGCTGACCCAGGCTTCTTTTGCAGGAAGATTGTGGAGGGC
  ATCTCCCAGCCCATCTGGCTGGTGAGTGACACACGGAGAGTGTCTGACATCCAGTGGTTT
  CGGGAGGCCTATGGGGCCGTGACGCAGACGGTCCGCGTTGTAGCGTTGGAGCAGAGCCGA
  CAGCAGCGGGGCTGGGTGTTCACGCCAGGGGTGGACGATGCTGAGTCAGAATGTGGCCTG
  GACAACTTCGGGGACTTTGACTGGGTCATCGAGAACCATGGAGTTGAACAGCGCCTGGAG
  GAGCAGTTGGAGAACCTGATAGAATTTATCCGCTCCAGACTTTAGTCACTAGGTTCTAGG
  AGTGAGCTGGGGCCTGCTGAGGTGGGGGTGGGGCTGACTCTGCAAAATGGGGGTGTCCCC
  CGATCCTGGCCGAGGTGAGGAACAGACAGGGGGGGTCTAGATTCTGAGGGGGTTGGTGGA
  TATTGGGCAAGGCAGGAAACCTCTGGAGACCTCATTTTCTCCATGGGGAAGACAGCCATG
  CTCTTCAGGAGGAGACTCCAAGGGCAAAGGAGGGTGTCTTGGCTGTGCTTGAAGGCGAAA
  CCCTGCCATATCCCCAGTGCCAGTCCCCTCAGCCTGTGGTGGCCTTGCATCCTGACTGGA
  TGTTCTCAGCCCCTTGTTCTGGGCAAGAACCCAGAGCTCCCCAGTGTGGATACTAATAAA
  CCTCTTGGAGCACACTCTCAAAACAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAACCTCGGG
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006556.3 unedited
  GACCATTTGTATACGACTCCTATAGGGCGGCCGGGAATTCGGCACGAGGGAAGGTTCTGG
  GCGGGGCTGGACTGTTCTAAGTGAGTTCGGGTGGGGGAGCTTCACGAGGGGAGGCTGCTC
  TGTGAAGGAACCGCCTTTCTCTCCGCGTGTCTCACCCTTTTCTCCCCATATCTGTTTGGA
  CATGAGCTGAGGGCACGGTCGCGGGCGGTCAGCCCTGTTCGCAGCTACGGCGAGGAGGGG
  CGCGATTGTTCCTTGTTGCCGCTCCGCTTAGTGGCCGCGTCCATTCCGCGCGGTGTCCCG
  ATTTTAGGGGTAGGGAGAAGTGTCAGCTTCAGGCATCGCGAGGCGTGGCGGCCCCATGGC
  CCCGCTGGGAGGCGCCCCGCGGCTGGTACTGCTGTTCAGCGGCAAGAGGAAATCCGGGAA
  GGACTTCGTGACCGAGGCGCTGCAGAGCAGACTTGGAGCTGATGTCTGTGCTGTCCTCCG
  GCTCTCTGGTCCACTCAAGGAACAGTATGCTCAGGAGCATGGCTTGAACTTCCAGAGACT
  CCTGGACACCAGCACCTACAAGGAGGCCTTTCGGAAGGACATGATCCGCTGGGGAGAGGA
  GAAACGCCAGGCTGACCCAGGCTTCTTTTGCAGGAAGATTGTGGAGGGCATCTCCCAGCC
  CATCTGGCTGGTGAGTGACACACGGAGAGTGTCTGACATCCAGTGGTTTCGGGAGGCCTA
  TGGGGCCGTGACGCAGACGGTCCGCGTTGTAGCGTTGGAGCAGAGCCGACAGCAGCGGGG
  CTGGGTGTTCACGCAGGGGTGGACGATGCTGGAGTCAGATGTGCTGACACTCGGGACTTG
  ACTGGTCATCGAGACATGAGTGACAGCGCTGAGGAGCAGTTGGGAGACCTGATAGAATTT
  AT
• Restriction Sites: Please inquire
• ACCN: NM_006556
• ORF Size: 579 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_006556.3, NP_006547.1
• RefSeq Size: 1307
• RefSeq ORF: 579
• Locus ID: 10654
• Domains: P-mevalo_kinase
• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Terpenoid backbone biosynthesis
• Gene Summary: This gene encodes a peroxisomal enzyme that is a member of the galactokinase, homoserine kinase, mevalonate kinase, and phosphomevalonate kinase (GHMP) family of ATP-dependent enzymes. The encoded protein catalyzes the conversion of mevalonate 5-phosphate to mevalonate 5-diphosphate, which is the fifth step in the mevalonate pathway of isoprenoid biosynthesis. Mutations in this gene are linked to certain types of porokeratosis including disseminated superficial porokeratosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).