DUSP12 (NM_007240) Human Untagged Clone

CAT#: SC319165

DUSP12 (untagged)-Human dual specificity phosphatase 12 (DUSP12)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DUSP12
• Synonyms: DUSP1; YVH1
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_007240.1 GGCACGAGGCCGCCTTGTCTCTGGGCGCGGCCATGTTGGAGGCTCCGGGCCCGAGTGATG
  GCTGCGAGCTCAGCAACCCCAGCGCCAGCAGAGTCAGCTGTGCCGGGCAGATGCTGGAAG
  TGCAGCCAGGATTGTATTTCGGTGGGGCCGCGGCCGTCGCGGAGCCAGATCACCTGAGGG
  AAGCGGGCATCACGGCCGTGCTAACAGTGGACTCGGAGGAGCCCAGCTTCAAGGCGGGGC
  CTGGGGTCGAGGATCTATGGCGCCTCTTCGTGCCAGCGCTGGACAAACCCGAGACGGACC
  TACTCAGCCATCTGGACCGGTGCGTGGCCTTCATCGGTCAGGCCCGCGCTGAGGGCCGTG
  CGGTGTTGGTGCACTGTCATGCAGGAGTCAGTCGAAGTGTGGCCATAATAACTGCTTTTC
  TCATGAAGACTGACCAACTTCCCTTTGAAAAAGCCTATGAAAAGCTCCAGATTCTCAAAC
  CAGAGGCTAAGATGAATGAGGGGTTTGAGTGGCAACTGAAATTATACCAGGCAATGGGAT
  ATGAAGTGGATACCTCTAGTGCAATTTATAAGCAATATCGTTTACAAAAGGTTACAGAGA
  AGTATCCAGAATTGCAGAATTTACCTCAAGAACTCTTTGCTGTTGACCCAACTACCGTTT
  CACAAGGATTGAAAGATGAGGTTCTCTACAAGTGTAGAAAGTGCAGGCGATCATTATTTC
  GAAGTTCTAGTATTCTGGATCACCGTGAAGGAAGTGGACCTATAGCCTTTGCCCACAAGA
  GAATGACACCATCTTCCATGCTTACCACAGGGAGGCAAGCTCAATGTACATCTTATTTCA
  TTGAACCTGTACAGTGGATGGAATCTGCTTTGTTGGGAGTGATGGATGGACAGCTTCTTT
  GCCCAAAATGCAGTGCCAAGTTGGGTTCCTTCAACTGGTATGGTGAACAGTGCTCTTGTG
  GTAGGTGGATAACACCTGCTTTTCAAATACATAAGAATAGAGTGGATGAAATGAAAATAT
  TGCCTGTTTTGGGATCACAAACAGGAAAAATATGAACATGATATTTTATAGCTTGGGAAG
  AAACTTGCAGATGATATGTGCTGCCTTTGCTTCTTATCATTCATGGCAGATTGTTTGTGC
  TTTCAACATTTCATTTGAAATGGGAGAAGATAAAATCACTTGATGTAACCTGGAAACTAT
  GCTTTACATGGCAATCAAAGCCTTTTGATCATGTACATTTTATTTGATATTAAAATCTTT
  TATAACCAGAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_007240.1 unedited
  GGCGTTTGTATACGACTCCTATAGGGCGGCCGGGAATTCGGCACGAGGCCGCCTTGTCTC
  TGGGCGCGGCCATGTTGGAGGCTCCGGGCCCGAGTGATGGCTGCGAGCTCAGCAACCCCA
  GCGCCAGCAGAGTCAGCTGTGCCGGGCAGATGCTGGAAGTGCAGCCAGGATTGTATTTCG
  GTGGGGCCGCGGCCGTCGCGGAGCCAGATCACCTGAGGGAAGCGGGCATCACGGCCGTGC
  TAACAGTGGACTCGGAGGAGCCCAGCTTCAAGGCGGGGCCTGGGGTCGAGGATCTATGGC
  GCCTCTTCGTGCCAGCGCTGGACAAACCCGAGACGGACCTACTCAGCCATCTGGACCGGT
  GCGTGGCCTTCATCGGTCAGGCCCGCGCTGAGGGCCGTGCGGTGTTGGTGCACTGTCATG
  CAGGAGTCAGTCGAAGTGTGGCCATAATAACTGCTTTTCTCATGAAGACTGACCAACTTC
  CCTTTGAAAAAGCCTATGAAAAGCTCCAGATTCTCAAACCAGAGGCTAAGATGAATGAGG
  GGTTTGAGTGGCAACTGAAATTATACCAGGCAATGGGATATGAAGTGGATACCTCTAGTG
  CAATTTATAAGCAATATCGTTTACAAAAGGTTACAGAGAAGTATCCAGAATTGCAGAATT
  TACCTCAAGAACTCTTTGCTGTTGACCCAACTACCGTTTCACAAGGATTGAAGATGAGTT
  CTCTACAAGTGTAGAAAGTGCAGCGATCATTATTTCGAAGTTCTAGTATTCTGGATCACC
  CGTGAAGAAGTGGACCTAATAGCCTTTGCCCACAGAGATGACACCATCTTCATGCTTACC
  ACAGGAGGCAGCTCATGTACATCTTATTTCATGACCTGTACAGTGATGCATCTGCCTTTG
  TTGGGATGATGATGACAGCTTCTTGCCAAAATGCATGCCCAGGTGGATTCCTCTCACCTG
  T
• Restriction Sites: Please inquire
• ACCN: NM_007240
• ORF Size: 1023 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_007240.1, NP_009171.1
• RefSeq Size: 1271
• RefSeq ORF: 1023
• Locus ID: 11266
• Domains: DSPc
• Protein Families: Druggable Genome, Phosphatase
• Gene Summary: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain. [provided by RefSeq, Jul 2008]