EXTL3 (NM_001440) Human Untagged Clone

CAT#: SC320147

EXTL3 (untagged)-Human exostoses (multiple)-like 3 (EXTL3)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: EXTL3
• Synonyms: BOTV; EXTL1L; EXTR1; ISDNA; REGR; RPR
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001440.2 CACTAACTCTTCTGGAAACGTGTCAGTGAAACAGAGATCGTTTTGTGGAATAGCAACCCA
  TGGTTATGGCGAGTGACCCGACGTGATCTGGGGGGCAGGCTGCAGAGGACTCATGACAGG
  CTATACCATGCTGCGGAATGGGGGCGCGGGGAACGGAGGTCAGACCTGCATGCTGCGCTG
  GTCCAACCGCATCCGCCTCACGTGGCTCAGCTTCACGCTCTTTGTCATCCTGGTCTTCTT
  CCCGCTCATCGCCCACTATTACCTCACCACTCTGGATGAGGCTGATGAGGCAGGCAAGCG
  GATTTTTGGTCCCCGGGTGGGGAACGAGCTGTGCGAGGTGAAGCACGTGCTGGATCTGTG
  CCGCATCCGGGAGTCGGTGAGTGAAGAGCTCCTGCAGCTGGAGGCCAAGCGCCAAGAGCT
  GAACAGCGAGATCGCCAAGCTGAATCTGAAGATCGAAGCCTGTAAGAAGAGCATTGAGAA
  CGCCAAGCAGGACCTGCTCCAGCTCAAGAATGTCATCAGCCAGACCGAGCATTCCTACAA
  GGAGCTCATGGCCCAGAACCAGCCCAAGCTGTCCCTGCCCATCCGACTGCTCCCAGAGAA
  GGACGATGCCGGCCTCCCTCCCCCGAAGGCCACTCGGGGCTGCCGGCTACACAACTGCTT
  TGATTATTCTCGTTGCCCTCTCACCTCTGGCTTCCCGGTCTACGTCTATGACAGTGACCA
  GTTTGTCTTTGGCAGCTACCTGGATCCCTTGGTCAAGCAGGCTTTTCAGGCGACAGCACG
  AGCTAACGTTTATGTTACAGAAAATGCAGACATCGCCTGCCTTTACGTGATACTAGTGGG
  AGAGATGCAGGAGCCGGTGGTGCTGCGGCCTGCTGAGCTGGAGAAGCAGTTGTATTCCCT
  GCCACACTGGCGGACGGATGGACACAACCATGTCATCATCAATCTGTCACGTAAGTCAGA
  TACACAGAACCTTCTCTATAACGTCAGTACTGGCCGTGCCATGGTGGCCCAGTCCACCTT
  CTACACTGTCCAGTACAGACCTGGCTTTGACTTGGTCGTATCACCGCTGGTCCATGCCAT
  GTCTGAGCCCAACTTCATGGAAATCCCACCACAGGTGCCGGTGAAGCGGAAATATCTCTT
  CACCTTCCAGGGCGAGAAGATTGAGTCTCTGAGGTCTAGCCTTCAGGAGGCCCGCTCCTT
  CGAAGAGGAAATGGAGGGCGACCCTCCCGCCGACTACGATGACCGGATCATTGCCACCCT
  GAAGGCGGTGCAGGACAGCAAGCTGGATCAGGTCCTGGTGGAATTCACCTGCAAAAACCA
  GCCCAAACCCAGCCTGCCAACTGAGTGGGCACTGTGTGGAGAGCGGGAGGACCGCTTGGA
  ATTGCTGAAGCTCTCCACCTTCGCCCTCATCATTACCCCCGGGGACCCTCGCTTGGTTAT
  TTCCTCTGGGTGTGCAACACGGCTCTTCGAAGCCCTGGAAGTCGGTGCCGTCCCGGTGGT
  GCTGGGGGAGCAGGTCCAGCTTCCCTACCAGGACATGCTGCAGTGGAACGAGGCGGCCCT
  GGTGGTGCCAAAGCCTCGTGTTACCGAGGTTCATTTCCTGCTCAGAAGCCTCTCCGATAG
  TGACCTCCTGGCTATGAGGCGGCAAGGCCGCTTTCTCTGGGAGACTTACTTCTCCACTGC
  TGACAGTATTTTTAATACCGTGCTGGCTATGATTAGGACTCGCATCCAGATCCCAGCCGC
  TCCCATCCGGGAAGAGGCGGCAGCTGAGATCCCCCACCGTTCAGGCAAGGCGGCTGGAAC
  TGACCCCAACATGGCTGACAACGGGGACCTGGACCTGGGGCCAGTGGAGACGGAGCCGCC
  CTACGCCTCACCCAGATACCTCCGCAATTTCACTCTGACTGTCACTGACTTTTACCGCAG
  CTGGAACTGTGCTCCAGGGCCTTTCCATCTTTTCCCCCACACTCCCTTTGACCCTGTGTT
  GCCCTCAGAGGCCAAATTCTTGGGCTCAGGGACTGGCTTTCGGCCTATTGGTGGTGGAGC
  TGGGGGTTCTGGCAAGGAATTTCAGGCAGCGCTTGGAGGCAATGTTCCCCGAGAGCAGTT
  CACGGTGGTGATGTTGACTTATGAGCGGGAGGAAGTGCTTATGAACTCTTTAGAGAGGCT
  GAATGGCCTCCCTTACCTGAACAAGGTCGTGGTGGTGTGGAATTCTCCCAAGCTGCCATC
  AGAGGACCTTCTGTGGCCTGACATTGGCGTCCCCATCATGGTGGTCCGTACTGAGAAGAA
  CAGTTTGAACAACCGATTCTTACCCTGGAATGAAATTGAGACAGAGGCCATCCTGTCCAT
  TGATGACGATGCTCACCTCCGCCATGACGAAATCATGTTTGGGTTCCGGGTGTGGAGAGA
  AGCTCGGGACCGCATCGTGGGCTTCCCTGGCCGTTACCACGCATGGGACATCCCCCATCA
  GTCCTGGCTCTACAACTCCAACTACTCCTGTGAGCTGTCCATGGTGCTGACAGGTGCTGC
  CTTCTTTCACAAGTATTATGCCTACCTGTATTCTTATGTGATGCCCCAGGCCATCCGGGA
  CATGGTGGATGAATACATCAACTGTGAGGACATTGCCATGAACTTCCTTGTCTCCCACAT
  CACTCGGAAGCCCCCCATCAAGGTGACCTCACGGTGGACATTCCGATGCCCAGGATGCCC
  TCAGGCCCTGTCTCATGATGACTCCCACTTCCACGAGCGGCACAAGTGCATCAACTTCTT
  CGTGAAGGTGTACGGCTACATGCCCCTCCTGTACACGCAGTTCAGGGTGGATTCTGTGCT
  CTTCAAGACACGCCTGCCCCATGACAAGACCAAGTGCTTCAAGTTCATCTAGGGGCAGCG
  CACGGTCTGGGGAAGAGGATGAGCAGAGGGAGGAAGATGGCTCCCAAGGTTCCTAGGCAT
  TGCAGGACCTTGGGCACATCTGCTGGTGGGTGGCCCAGAGCCTCTGCTGGAAGGGGCAGC
  AGGAGGAGTGGAAGGAAACCGCTGCCTTTATCTTGAAGTCAGCCACACTGGGCCTGGAGC
  CCTGGGCGGAGTCCCCGGGGTTCCCCACACAGGGCACTGACTGATAGCTTACACTGAGGA
  CTGTGGCGACTCTGCAGAGTCACTCACACCGTTCGTACGCCCAGGACAGCTGGTTCGTGG
  TTTTTACATTCAATAACAACTATTATGATTATTTAAAAAAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_001440
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001440.2, NP_001431.1
• RefSeq Size: 6172 bp
• RefSeq ORF: 2760 bp
• Locus ID: 2137
• Cytogenetics: 8p21.1
• Domains: Exostosin
• Protein Families: Transmembrane
• Protein Pathways: Heparan sulfate biosynthesis, Metabolic pathways
• Gene Summary: 'This gene encodes a single-pass membrane protein which functions as a glycosyltransferase. The encoded protein catalyzes the transfer of N-acetylglucosamine to glycosaminoglycan chains. This reaction is important in heparin and heparan sulfate synthesis. Alternative splicing results in the multiple transcript variants. [provided by RefSeq, Nov 2012]'
  Transcript Variant: This variant (1) represents the longest transcript and encodes the functional protein.