PLA2G12A (NM_030821) Human Untagged Clone

CAT#: SC320348

PLA2G12A (untagged)-Human phospholipase A2, group XIIA (PLA2G12A)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PLA2G12A
• Synonyms: GXII; PLA2G12; ROSSY
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_030821.3 GCTGGCCCAGGTGAGCGGGCGCGCTGGTCCAGGTGAGCGGGCGCGTCCCCGCGACGGCGC
  TGCCTGCCCGAGGCGGTTCACGTAAAGACAGCGAGATCCTGAGGGCCAGCCGGGAAGGAG
  GCGTGGATATGGAGCTGGCTGCTGCCAAGTCCGGGGCCCGCGCCGCTGCCTAGCGCGTCC
  TGGGGACTCTGTGGGGACGCGCCCCGCGCCGCGGCTCGGGGACCCGTAGAGCCCGGCGCT
  GCGCGCATGGCCCTGCTCTCGCGCCCCGCGCTCACCCTCCTGCTCCTCCTCATGGCCGCT
  GTTGTCAGGTGCCAGGAGCAGGCCCAGACCACCGACTGGAGAGCCACCCTGAAGACCATC
  CGGAACGGCGTTCATAAGATAGACACGTACCTGAACGCCGCCTTGGACCTCCTGGGAGGC
  GAGGACGGTCTCTGCCAGTATAAATGCAGTGACGGATCTAAGCCTTTCCCACGTTATGGT
  TATAAACCCTCCCCACCGAATGGATGTGGCTCTCCACTGTTTGGTGTTCATCTTAACATT
  GGTATCCCTTCCCTGACAAAGTGTTGCAACCAACACGACAGGTGCTATGAGACCTGTGGC
  AAAAGCAAGAATGACTGTGATGAAGAATTCCAGTATTGCCTCTCCAAGATCTGCCGAGAT
  GTACAGAAAACACTAGGACTAACTCAGCATGTTCAGGCATGTGAAACAACAGTGGAGCTC
  TTGTTTGACAGTGTTATACATTTAGGTTGTAAACCATATCTGGACAGCCAACGAGCCGCA
  TGCAGGTGTCATTATGAAGAAAAAACTGATCTTTAAAGGAGATGCCGACAGCTAGTGACA
  GATGAAGATGGAAGAACATACCTTTGACAAATAACTAATGTTTTTACAACATAAAACTGT
  CTTATTTTTGTGAAAGGATTATTTTGAGACCTTAAAATAATTTATATCTTGATGTTAAAA
  CCTCAAAGCAAAAAAAGTGAGGGAGATAGTGAGGGGAGGGCACGCTTGTCTTCTCAGGTA
  TCTTCCCCAGCATTGCTCCCTTACTTAGTATGCCAAATGTCTTGACCAATATCAAAAACA
  AGTGCTTGTTTAGCGGAGAATTTTGAAAAGAGGAATATATAACTCATTTTCACAACCACA
  TTTACCAAAAAAAGAGATCAAATATAAAATTCATCATAATGTCTGTTCAACATTATCTTA
  TTTGGAAAATGGGGAAATTATCACTTACAAGTATTTGTTTACTATGAAATTTTAAATACA
  CATTTATGCCTAGAAGGAACGGACTTTTTTTTTTCTATTTTAATTACACATAATATGTAA
  TTAAAGTACAACATAATATGTTGTTTCTCTGTAGCCCGTTGAGCATATGAGTAAGTCACA
  TTTCTATTAGGACTACTTACAAGGACAAGGTTTCCATTTTTCCAGTTGTAAAATTGGAAC
  CATCAGCTGATAACCTCGTAGGGAGCAACCCCAGGATAGCTAAGTGTTATGTAATATGCC
  TAGAAGGTGATGTGAATGCGATTCAGAAGCATAGCCACTCCCATTTTATGAGCTACTCAC
  ATGACAAATGTCATCTTTTGCTATAACCTTTGCCAAGTTAGAGAAAAGATGGATTTAATG
  AGATAAATGAAAAGATATTTAACCTAATATATCAAGGCAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_030821.3 unedited
  GGACGACTGAGACTCTAAGTGCGGCTACTCACGTCCCGCGGCCGGGATTCGTCGACTGGA
  TCCGGTACCGAGGAGATCTGCTTAACTAGTTAGCGGACCGACGCGTTAAGCGGCCGCGAA
  TTCAGATCCACAAGTTTGTACAAAAAAGCAGGCTTGTAAAACGACGGCCAGTAACTATAA
  CGGTCCTAAGGTAGCGAGGCCTGGGTGGCGAATTCGGCACGAGGGCTGGCCCAGGTGAGC
  GGGCGCGCTGGTCCAGGTGAGCGGGCGCGTCCCCGCGACGGCGCTGCCTGCCCGAGGCGG
  TTCACGTAAAGACAGCGAGATCCTGAGGGCCAGCCGGGAAGGAGGCGTGGATATGGAGCT
  GGCTGCTGCCAAGTCCGGGGCCCGCGCCGCTGCCTAGCGCGTCCTGGGGACTCTGTGGGG
  ACGCGCCCCGCGCCGCGGCTCGGGGACCCGTAGAGCCCGGCGCTGCGCGCATGGCCCTGC
  TCTCGCGCCCCGCGCTCACCCTCCTGCTCCTCCTCATGGCCGCTGTTGTCAGGTGCCAGG
  AGCAGGCCCAGACCACCGACTGGAGAGCCACCCTGAAGACCATCCGGAACGGCGTTCATA
  AGATAGACACGTACCTGAACGCCGCCTTGGACCTCCTGGGAGGCGAGGACGGTCTCTGCC
  AGTATAAATGCAGTGACGGATCTAAGCCTTTCCCACGTTATGGTTATAAACCCTCCCCAC
  CGAATGGATGTGGCTCTCCACTGTTTGGTGTTCATCTTAACATTGGTATCCCTTCCCTGA
  CAAAGTGTTGCAACCAACACGACAGGTGCTATGAGACCTGTGGCAAAGCAAGAATGACTG
  TGATGAAGAATTCAGTATTGCCTCTTCCAGATCTGCCGAGATGTACAGGAAAACACTAGA
  CTAACTCAGCATGTTCAGGCATGGTGAAACAAACCAGTGGGGAGCCTCTTTTGTTTGAAC
  AG
• Restriction Sites: Please inquire
• ACCN: NM_030821
• ORF Size: 570 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_030821.3, NP_110448.2
• RefSeq Size: 1699
• RefSeq ORF: 570
• Locus ID: 81579
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: alpha-Linolenic acid metabolism, Arachidonic acid metabolism, Ether lipid metabolism, Fc epsilon RI signaling pathway, Glycerophospholipid metabolism, GnRH signaling pathway, Linoleic acid metabolism, Long-term depression, MAPK signaling pathway, Metabolic pathways, Vascular smooth muscle contraction, VEGF signaling pathway
• Gene Summary: Secreted phospholipase A2 (sPLA2) enzymes liberate arachidonic acid from phospholipids for production of eicosanoids and exert a variety of physiologic and pathologic effects. Group XII sPLA2s, such as PLA2G12A, have relatively low specific activity and are structurally and functionally distinct from other sPLA2s (Gelb et al., 2000 [PubMed 11031251]). [supplied by OMIM, Mar 2008]