CACNG6 (NM_145814) Human Untagged Clone

CAT#: SC320489

CACNG6 (untagged)-Human calcium channel, voltage-dependent, gamma subunit 6 (CACNG6), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CACNG6
• Synonyms: 2310033H20Rik; AW050150; calcium channel, voltage-dependent, gamma subunit 6; MGC144251; MGC144252; voltage-dependent calcium channel gamma-6 subunit
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_145814.1 CCAAGTCCTCTGTTCTCAAACTCTGAGCCCAAGGGAACCCCGGCCACATCTCCTCCAAAC
  ACACACAGGACCTCAGGTCCCTTCCTGGGTACCCCAAACTCTTAGCCCTAGTGGGGTGCT
  CAGATCTCTCAGGAAAACCAGTTTCCCTTTTGTTAACCCCCCAGCGGGGACCCCAAAGCA
  GCCCCTTGGAGCTGCAGGGAGCTTCAGCGGGCACCAGTTCTCATTCCTCTGGAGCTCTTG
  GGGGGACTCCCTCCTGGGAAGCCGAATTCTATCTCTAAACCTCAGGGTGGGGGCCTTGTT
  TTTCCTCTGGGCCCCGTCTTCTTTGCCAAGTTCTTGAGGGCAACCTAGACCCTCCTCTGA
  ACCCCAGAGGCTTCCCCAGCCCTGGGGATCGTTTTTCTCTTCTGAACCCCAGAAGCAATC
  TCGACTTTCGCATTTGAGATTCCAGACAGGACTCGGCTCTCCCTCTTTCATACCCAGGGG
  AAACTGAGTCCCTCACCCCCTTCAAGACCCCAGGCCGCTCCTCGCTCCCGCCCCTCGAGG
  CCCTTCGCCGGCTCTGCCTCCTCCCCCTTCCCGACCCCACCGGCCATAAGATGATGTGGT
  CCAACTTCTTCCTGCAAGAGGAGAACCGGCGGCGGGGGGCCGCGGGCCGGCGGCGGGCGC
  ACGGGCAGGGCAGGTCGGGGCTGACGCCCGAGCGCGAGGGGAAGGTGAAGCTGGCGCTGC
  TGCTGGCCGCCGTGGGCGCCACGCTGGCGGTGCTGTCCGTGGGCACCGAGTTCTGGGTGG
  AGCTCAACACCTACAAGGCCAACGGCAGCGCCGTGTGCGAAGCGGCCCACCTGGGGCTGT
  GGAAGGCGTGCACCAAGCGGCTGTGGCAGGCGGACGTGCCCGTGGACAGGGACACCTGCG
  GCCCCGCGGAGCTGCCCGGAGAAGCAAACTGCACCTATTTTAAATTCTTCACCACGGGGG
  AGAATGCACGCATCTTTCAGAGAACCACAAAGAAAGAGGTGAATCTGGCAGCTGCGGTGA
  TAGCAGTGCTGGGCCTGGCAGTCATGGCCTTGGGGTGCCTCTGTATCATCATGGTGCTCA
  GTAAAGGTGCAGAGTTCCTGCTCCGAGTTGGAGCCGTCTGCTTTGGCCTCTCAGGCCTGC
  TGCTCTTGGTGAGCCTGGAGGTGTTCCGGCATTCCGTGAGGGCCCTGCTGCAGAGAGTCA
  GCCCGGAGCCTCCCCCGGCCCCACGCCTCACCTACGAGTACTCCTGGTCCCTGGGCTGCG
  GCGTGGGGGCCGGCCTGATCCTGCTGTTGGGGGCCGGCTGCTTTCTGCTGCTCACACTGC
  CTTCCTGGCCCTGGGGGTCCCTCTGTCCCAAGCGGGGGCACCGGGCCACCTAGAGCCACG
  CGTGAGACTTCTCTAAGCAACCACCGAGCCCTTTGACCTTCTCCATTGTACCCCCAAGAT
  CTTTTTGCCCCATCTCCTAGAGAAACTGTGTTCTCCCTGCTCGGGGGCCCATGTTTTTTT
  ACACGCCTGCCTCCTGTCCCCTTATCCTTTCTCCCTCTGTAAATACGTTTTTCTCTGTGG
  CTGTATGTGGGTTGCTTGGGGGTGGGATGGGAAGAGGCTCTTTGCAAACGAGGGTCCCCA
  GAGAAGACTGGCGGGGACCTGATGGGGTAGCTGGGGTGTGGGGTTGGGGGATGAGGTCAG
  GGGGTCTTGGGTGGGAGTTGGGGGCCCCTTCATTTCCCAGGTCTGGATCGATTCACTTGC
  CGGGAGAGACTTTTTACAACTCATCTGCAGCTCCGGGTGCGGTTGGGGGAGATAGCGAAG
  GGTCTGGCCTCGCTGTGATCTGATTTGGGATTAAAGGTTTGGAAATTTAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_145814.1 unedited
  GGAGCACTTGTAGTACGACTCCTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTAC
  CGAGGAGATCTGCCGCCGCGATCGCGGCGCGCCAGATCTCAAGCTTAACTAGTTAGCGGA
  CCGACGCGTTAAGCGGCCGCGAATTCAGATCCACAAGTTTGTACAAAAAAGCAGGCTTGT
  AAAACGACGGCCAGTAACTATAACGGTCCTAAGGTAGCGAGGCCTGGGTGGCGAATTCGG
  CACGAGGCCAAGTCCTCTGTTCTCAAACTCTGAGCCCAAGGGAACCCCGGCCACATCTCC
  TCCAAACACACACAGGACCTCAGGTCCCTTCCTGGGTACCCCAAACTCTTAGTCCTAGTG
  GGGTGCTCAGATCTCTCAGGAAAACCAGTTTCCCTTTTGTTAACCCCCCAGCGGGGACCC
  CAAAGCAGCCCCTTGGAGCTGCAGGGAGCTTCAGCGGGCACCAGTTCTCATTCCTCTGGA
  GCTCTTGGGGGGACTCCCTCCTGGGAAGCCGAATTCTATCTCTAAACCTCAGGGTGGGGG
  CCTTGTTTTTCCTCTGGGCCCCCGTCTTCTTTGCCAAGTTCTTGAGGGCAACCTAGACCC
  CTCCTCTGAACCCCAGAGGCTTTCCCCAGCCCCTGGGGATCGTTTTTCTCTTCTGAACCC
  CAGAAGCAATCTCGACTTTCGCATTTGAGATTCCAGACAGGACTCGGCTCTCCCTCTTTC
  ATACCCAGGGGAAACTGAGTCCCTCACCCCCTTTCAAGACCCCAGCCCGCTCCTCGCTCC
  CGCCCTCGAGGCCCTTTCGCCGGCTCTGCCTCTCCCCTTCCCGACCCCACCGACATAGAT
  GATGTGGTCCACTTCTTCTGCAGAAGAGACCGCGCGGGGCCGCGGCGGCGGCGCGCACGC
  AGCAAGTCCGGGCCTGACCCGACCGCGAGGGCGGAGCTTGACTGCTGCTGACCGCTGGGC
  CCACGCCTGGGCGGTGCCTGTCCTGAG
• Restriction Sites: Please inquire
• ACCN: NM_145814
• ORF Size: 783 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_145814.1, NP_665813.1
• RefSeq Size: 1886
• RefSeq ORF: 783
• Locus ID: 59285
• Protein Families: Druggable Genome, Ion Channels: Other, Transmembrane
• Protein Pathways: Arrhythmogenic right ventricular cardiomyopathy (ARVC), Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM), MAPK signaling pathway
• Gene Summary: Voltage-dependent calcium channels are composed of five subunits. The protein encoded by this gene represents one of these subunits, gamma, and is one of two known gamma subunit proteins. This particular gamma subunit is an integral membrane protein that is thought to stabilize the calcium channel in an inactive (closed) state. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members that function as transmembrane AMPA receptor regulatory proteins (TARPs). Alternative splicing results in multiple transcript variants. Variants in this gene have been associated with aspirin-intolerant asthma. [provided by RefSeq, Dec 2010]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).