Selenophosphate synthetase 2 (SEPHS2) (NM_012248) Human Untagged Clone

CAT#: SC320578

SEPHS2 (untagged)-Human selenophosphate synthetase 2 (SEPHS2) (10ug), (Note: selenocysteine protein, Internal stop codon present. see reference data summary below)

Specifications

Product Data

• Type: Human Untagged Clone
• Symbol: SEPHS2
• Synonyms: SPS2
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_012248.2 GCCGTGGGTCTGACGGCTTGAGTAGCGCTAGGGAGAATCCCTGCAGGTAATATTTGACTT
  TTGCTTCATATTAATCTGAGTGGAAAATAAAAGGGCCCTCTTCTCCTCTCGCTTCCCTGC
  CGGGCAGGCGCCATGGCGGAAGCCTCGGCGACGGGCGCCTGCGGAGAGGCGATGGCAGCG
  GCGGAAGGCTCCTCGGGCCCGGCGGGCTTGACTCTGGGCCGGAGCTTCTCGAACTACCGG
  CCCTTCGAGCCCCAGGCGTTGGGCCTCAGCCCGAGCTGGCGGCTGACGGGCTTCTCCGGC
  ATGAAGGGCTGAGGCTGCAAGGTCCCGCAGGAGGCGCTGCTCAAACTCCTGGCGGGACTG
  ACGCGGCCGGACGTGCGGCCCCCGCTGGGCCGGGGCCTGGTGGGTGGCCAGGAAGAGGCG
  TCCCAGGAAGCCGGCCTGCCGGCAGGAGCGGGCCCCAGCCCCACCTTTCCAGCCCTGGGC
  ATCGGGATGGACTCCTGCGTCATCCCCCTGAGGCACGGGGGCCTGTCACTGGTGCAGACC
  ACGGACTTCTTTTACCCCTTGGTAGAAGATCCCTACATGATGGGGCGCATAGCTTGTGCC
  AACGTGCTGAGTGACCTCTACGCCATGGGGATTACTGAGTGTGACAACATGTTGATGTTA
  CTCAGCGTCAGCCAGAGTATGAGTGAGGAGGAACGCGAAAAGGTAACGCCACTCATGGTC
  AAAGGCTTTCGGGATGCGGCTGAGGAAGGAGGGACGGCAGTGACCGGTGGGCAAACGGTG
  GTCAACCCTTGGATTATAATCGGTGGAGTTGCCACTGTAGTATGCCAACCAAATGAGTTC
  ATAATGCCGGACAGCGCCGTCGTTGGGGACGTGCTGGTGTTAACCAAACCGTTAGGAACC
  CAGGTTGCTGTCAATGCCCACCAATGGCTGGATAATCCTGAAAGATGGAATAAAGTAAAG
  ATGGTGGTCTCCAGAGAAGAGGTGGAGCTGGCCTATCAGGAAGCCATGTTCAATATGGCT
  ACCCTCAACAGAACTGCTGCAGGTTTAATGCACACATTTAATGCCCATGCGGCCACAGAT
  ATCACAGGCTTTGGCATTCTAGGACACTCCCAGAACCTTGCAAAACAACAAAGAAATGAA
  GTGTCCTTTGTTATTCATAATCTGCCAATAATTGCCAAGATGGCTGCCGTCAGCAAGGCC
  AGTGGACGGTTTGGGCTTCTTCAAGGAACCTCAGCTGAAACCTCTGGGGGATTACTGATT
  TGTCTGCCAAGAGAACAGGCGGCTCGCTTTTGTTCTGAAATCAAATCCTCCAAGTACGGA
  GAGGGTCACCAAGCGTGGATCGTTGGCATTGTGGAAAAGGGAAACCGAACGGCCCGGATC
  ATTGACAAGCCGCGAGTTATTGAAGTCCTGCCTCGTGGGGCCACAGCTGCTGTTCTTGCT
  CCTGACAGTTCAAATGCCTCCTCTGAGCCTAGCTCGTGAGATGAAAGAACAGAAGTTGTT
  TGGACCTTAGAGCCATTGTCCACAATCACGGATGGTTCTCAAGAGTTGATTGTAAGAAAT
  TTCCAAAGAAGGCTGCCTGCATAGTGGTTCCGGCTGCCCTTTCTAGGTGATTGGAATCAG
  CCCATCTAAAGCAGTCTTTATATGCATTCCGAGGCCAGAGTAACATTTTGAACTTTGGGG
  GGATATTTGTTCATCACTTGGGTAGAAGAGGAGCAAAAATACCTCTGTTTTCTCTTGCCA
  AAGTAAGATGAAGCTATTCCAGGTTGAGGGATTTTTCTTTGCACGGGGTTGATTAATTTC
  TGCACAGGGAGTGAGATTATTAAAGTAACACACACACAAAGTAAATTGCAAAATGAAAAA
  AATTAGAAGCAAATGAGTTTTGGACCAATATTGTTGATAAATCTAAATTGTTAAGAGAGA
  TCTTATAATGCAACATCAAATTCTTTATTCAATTTTACTGAAGTACTGGCTCTTTCCTGC
  TCTGGACAAGAATTGAGCAACTTGTCTGATGACTGGGAAAGGAGGACCTGCAACCATCTG
  ACTTGGTCTCTGTTAATGACGTCTCTCCCTCTAAACCCCATTAAGGACTGGGAGAGGCAG
  AGCAAGCCTCAGAGCCCAGGCCTCAGTGGTCATTAAGATGTTAAGTCTTTTGCGGCAGAT
  TCCTGGTGATTTGATCAATAAAGAGTAATTTCTTGCTAAATAAATAAAAGAAACCTTGTT
  GAAAAACTAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_012248.2 unedited
  GCATTGTATACGACTACTATAGGGCGGAGGGACACGGCACGAGGGCCGTGGGTCTGACGG
  CTGAGTAGCGCTAGGGAGAATCCCTGCAGGTAATATTTGACTTTTGCTTCATATTAATCT
  GAGTGGAAAATAAAAGGGCCCTCTTCTCCTCTCGCTTCCCTGCCGGGCAGGCGCCATGGC
  GGAAGCCTCGGCGACGGGCGCCTGCGGAGAGGCGATGGCAGCGGCGGAAGGCTCCTCGGG
  CCCGGCGGGCTTGACTCTGGGCCGGAGCTTCTCGAACTACCGGCCCTTCGAGCCCCAGGC
  GTTGGGCCTCAGCCCGAGCTGGCGGTTGTTGGGCTTCTCCGGCATGATTTTTCTGAGGCT
  GCAAGGTCCCGCAGGAGGCGCTGCTCAAACTCCTGGCGGGACTGACGCGGCCGGACGTGC
  GGCCCCCGCTGGGCCGGGGCCTGGTGGGTGGCCAGGAAGAGGCGTCCCAGGAAGCCGGCC
  TGCCGGCAGGAGCGGGCCCCAGCCCCACCTTTCCAGCCCTGGCATCGGGATGGACTCCTG
  CGTCATCCCCCTGAGGCACGGGGGCCTGTCACTGGTGCAGACCACGGACTTCTTTTACCC
  CTTGGTAGAAGATCCCTACATGATGGGGCGCATAGCTTGTGCCAACGTGCTGAGTGACCT
  CTACGCCATGGGGATTACTGAGTGTGACACATGTTGATGTTACTCAGCGTCAGCCAGAGT
  ATGAGTGAGGAGGAACGCGAAAGGTAACGCCACTCATGGTCAAAGGCTTTCGGATGCTGC
  TGATGAGAGGACGCAGTGACCGGTGGGCAAACGGTGTCAACCTTGATTATATCGGTGGAG
  TTGCCACTGTAGTATGCCACCAATGTTCATAATGCCGACAGGCCCGTCCTTTGGACCGGC
  TGGTGGTTAACCAAACCGTTATGA
• Restriction Sites: Please inquire
• ACCN: NM_012248
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). The expression of this clone is not guaranteed due to the nature of selenoproteins.
• OTI Annotation: This clone encodes a selenoprotein containing the rare amino acid selenocysteine (Sec). Sec is encoded by UGA codon, which normally signals translational termination. Expression of this clone is not guaranteed due to the nature of selenoproteins.

Reference Data

• RefSeq: NM_012248.2, NP_036380.2
• RefSeq Size: 2291
• Locus ID: 22928
• Domains: AIRS
• Protein Pathways: Metabolic pathways, Selenoamino acid metabolism
• Gene Summary: This gene encodes an enzyme that catalyzes the production of monoselenophosphate (MSP) from selenide and ATP. MSP is the selenium donor required for synthesis of selenocysteine (Sec), which is co-translationally incorporated into selenoproteins at in-frame UGA codons that normally signal translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element, which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein is itself a selenoprotein containing a Sec residue at its active site, suggesting the existence of an autoregulatory mechanism. It is preferentially expressed in tissues implicated in the synthesis of selenoproteins and in sites of blood cell development. A pseudogene for this locus has been identified on chromosome 5. [provided by RefSeq, May 2017]