TNFAIP8 (NM_014350) Human Untagged Clone

CAT#: SC320774

TNFAIP8 (untagged)-Human tumor necrosis factor, alpha-induced protein 8 (TNFAIP8), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TNFAIP8
• Synonyms: GG2-1; MDC-3.13; NDED; SCC-S2; SCCS2
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_014350.2 GGCTCCGGGGGCGGACTCCCGCCGCCCAGCTGACACGCGATTCGTCACTCTTGCAGAACT
  TTCCCCCTGAAAATCCCTGCACCAGAACCCGCTCTCCCGCCCCGGGGAGGTTTTGATTTT
  AGTGGCTTTCTTCCTTTTATTTTCCGTCGTGTGCGGATTTCGCTGCAGAGCGAACTTGCG
  GCTCGTCCGAGTACATGTGAGCGGTAATCGCCCCTGCAGCTGGTTATCCTGACATTATGC
  ACTCCGAAGCAGAAGAATCCAAGGAAGTGGCCACAGATGTCTTTAATTCCAAAAACCTGG
  CCGTTCAGGCACAAAAGAAGATCTTGGGTAAAATGGTGTCCAAATCCATCGCCACCACCT
  TAATAGACGACACAAGTAGTGAGGTGCTGGATGAGCTCTACAGAGTGACCAGGGAGTACA
  CCCAAAACAAGAAGGAGGCAGAGAAGATCATCAAGAACCTCATCAAGACAGTCATCAAGC
  TGGCCATTCTTTATAGGAATAATCAGTTTAATCAAGATGAGCTAGCATTGATGGAGAAAT
  TTAAGAAGAAAGTTCATCAGCTTGCTATGACCGTGGTCAGTTTCCATCAGGTGGATTATA
  CCTTTGACCGGAATGTGTTATCCAGGCTGTTAAATGAATGCAGAGAGATGCTGCACCAAA
  TCATTCAGCGCCACCTCACTGCCAAGTCACATGGACGGGTTAATAATGTGTTTGATCATT
  TTTCAGATTGTGAATTTTTGGCTGCCTTGTATAATCCTTTTGGGAATTTTAAACCCCACT
  TACAAAAACTATGTGATGGTATCAACAAAATGTTGGATGAAGAGAACATATGAGCACATG
  AGTTAAGATTGTGACTGATCATGATTTATTTGAAGATGGAGCACTGCTGATTTATGAAGG
  AAAAAAGAAGAATTTTCTAAAGATTACACATATTTCAGAAAGACTTTACCCAATTCAGTT
  GTCAGACATAATGATTTATTTGAAGGCTTGTTTTATTTGAAGAAAAGCATATTGCCAAAA
  ATTCTGGTTAAAAGCTTCCTAACGGGTAACAGACCATGGGAGAGATATGTGGTTGGGTAA
  TGCAAATGTAGTTATACAAAGAAAAATACAGATGTCTCCAGACCTGAGGACTTTTTAATA
  GGGCAGTTGTTGTGTTGGTGGCACATTGGATATTTCTAACATGTACAAAGCTATGTATTT
  TGATTTACTTTCATTTCTTGCTATGTATATGTACTTTTCTTAAAATGCCAAGAACTTTCT
  CTTGCTATCATTGCTCCTTTTGAAACAATTCAATTTTCATGTCTACAGCTGACTGTTTTG
  TTAAGATTGAGTCATCGACATTCAGGATTTAAGTCTGAGGTAGTCAACCCTCAGGAAAAA
  AAAAATGGCTTATCTGAAATCAGTACTGTGGAAATGAACTATATTAGCTATTATGAATAA
  TGTCCAGTATAAGAATATGCTTCTGGAATTGAGTTCTCCTTTTAAGTACCAATGATACTT
  AAATTTCTCAGAAATGTAATGGTGTGTCATTGCCTTGAAATGCTTGCTTAGGGCTTCTTT
  TATGTTATCTTAAAAAGTGCTGGTGAATTTTCCATTTTTTACATCCATTTCACATGTAAG
  AGACAAAAAAGTCTAGATTGGTCTTGATATTGAGATAATAAAAAGTAAGTAGCATTAAGA
  AAGGTAACAATCTTCATTCTACAGATGAACTCATTGAAACAATTTAGGGGAATGAGGGGC
  AAAAGGGGAGAAATACTGCTAAAGAACATGAGCATAAAAATGCGTGCGTTTCAGTGTTTA
  AGAAGGCTTGATAAAGAATGTCACTTTTTTATTTAACTGATAAGATTTTTGTTATTTTTT
  ACTTTGATAAGTAAACCAAAGAATATTTGTATTTCAAGCAGTTTGTGTGGTGTTTCTATA
  TAATTTTCTGTGTATAAATAATAAAGTAGGCATTTGTTTATTTTGTAAAAAAGAAATGAA
  AATCTGCTGGCCAGCTATGTCCTCTAGGAAATGACAGACCCAACCACCAGCAATAAACAT
  TTCCATTGTCGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_014350.2 unedited
  GCGATTGTATACGACTCCTATAGGGCGGGGGGAAATCGGCCTTACGGCCGGGGGGCTCCG
  GGGGCGGACTCCCGCCGCCCAGCTGACACGCGATTCGTCACTCTTGCAGAACTTTCCCCC
  TGAAAATCCCTGCACCAGAACCCGCTCTCCCGCCCCGGGGAGGTTTTGATTTTAGTGGCT
  TTCTTCCTTTTATTTTCCGTCGTGTGCGGATTTCGCTGCAGAGCGAACTTGCGGCTCGTC
  CGAGTACATGTGAGCGGTAATCGCCCCTGCAGCTGGTTATCCTGACATTATGCACTCCGA
  AGCAGAAGAATCCAAGGAAGTTTTTTTTTTTATGTCTTTAATTCCAAAAACCTGGCCGTT
  CAGGCACAAAAGAAGATCTTGGGTAAAATGGTGTCCAAATCCATCGCCACCACCTTAATA
  GACGACACAAGTAGTGAGGTGCTGGATGAGCTCTACAGAGTGACCAGGGAGTACACCCAA
  AACAAGAAGGAGGCAGAGAAGATCATCAAGAACCTCATCAAGACAGTCATCAAGCTGGCC
  ATTCTTTATAGGAATAATCAGTTTAATCAAGATGAGCTAGCATTGATGGAGAAATTTAAG
  AAGAAAGTTCATCAGCTTGCTATGACCGTGGTCAGTTTCCATCAGGTGGATTATACCTTT
  TGACCGGAATGTGTTATCCAGCTGTTAAATGAATGCAGAGAGATGCTGCACCAAATCATT
  CAGCCGCCCACCTCACCTGCCCAGTCACATGACGGGTAATAATGTGTAGATCATTTTTCA
  AATTGTGAATTTTGCTGCCTTGATATCCTTTGGGAATTAACCCCACTTACAAAAACCTAT
  GTGATGTATCACAAATGTGGATGAAGAGAACATATGACCCCTGGACTAACATGGAACTGA
  TCTGATCTATTCGCAGATGGACCCCGGGTATTTTCGAGCGCATAAAGAAAATTCTCAGAA
  T
• Restriction Sites: Please inquire
• ACCN: NM_014350
• ORF Size: 597 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_014350.2, NP_055165.2
• RefSeq Size: 2015
• RefSeq ORF: 597
• Locus ID: 25816
• Protein Families: Druggable Genome
• Gene Summary: Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation. [UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (1) encodes isoform a. Both variant 1 and 3 encode the same isoform.