GMPR2 (NM_001002000) Human Untagged Clone

CAT#: SC320877

GMPR2 (untagged)-Human guanosine monophosphate reductase 2 (GMPR2), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: GMPR2
• Synonyms: GMPR 2
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001002000.1 GGTAGAAGAAGGAAGTGTAGCGGGCCCTCAGATTCATCGCTACCCCGAGGCTAAGCGCCA
  TGCCTCATATTGACAACGATGTGAAACTGGACTTCAAGGATGTCCTTTTGAGGCCCAAAC
  GCAGTACCCTTAAGTCTCGAAGTGAGGTGGATCTCACAAGATCCTTTTCATTTCGGAACT
  CAAAGCAGACATACTCTGGGGTTCCCATCATTGCTGCCAATATGGATACTGTGGGCACCT
  TTGAGATGGCCAAGGTTCTCTGTAAGTTCTCTCTCTTCACTGCTGTCCATAAGCACTATA
  GCCTCGTTCAGTGGCAAGAGTTTGCTGGCCAGAATCCTGACTGTCTTGAGCATCTGGCTG
  CCAGCTCAGGCACAGGCTCTTCTGACTTTGAGCAGCTGGAACAGATCCTGGAAGCTATTC
  CCCAGGTGAAGTATATATGCCTGGATGTGGCAAATGGCTACTCTGAACACTTTGTTGAAT
  TTGTAAAAGATGTACGGAAGCGCTTCCCCCAGCACACCATCATGGCAGGGAATGTGGTAA
  CAGGAGAGATGGTAGAAGAGCTCATCCTTTCTGGGGCTGACATCATCAAAGTGGGAATTG
  GGCCAGGCTCTGTGTGTACTACTCGGAAGAAAACTGGAGTGGGGTATCCACAGCTCAGCG
  CAGTGATGGAGTGTGCAGATGCTGCTCATGGCCTCAAAGGCCACATCATTTCAGATGGAG
  GTTGCAGCTGTCCTGGGGATGTGGCCAAGGCTTTTGGGGCAGGAGCTGACTTCGTGATGC
  TGGGTGGCATGCTGGCTGGGCACAGTGAGTCAGGTGGTGAGCTCATCGAGAGGGATGGCA
  AGAAGTACAAGCTCTTCTATGGAATGAGTTCTGAAATGGCCATGAAGAAGTATGCTGGGG
  GCGTGGCTGAGTACAGAGCCTCAGAGGGAAAGACAGTGGAAGTTCCTTTTAAAGGAGATG
  TGGAACATACCATCCGAGACATCCTAGGAGGGATCCGCTCTACGTGTACCTATGTGGGAG
  CAGCTAAGCTCAAAGAGTTGAGCAGGAGAACTACCTTCATCCGAGTCACCCAGCAGGTGA
  ATCCAATCTTCAGTGAGGCGTGCTAGACCTGAGCAGTTCTACCCTCCCAAGGCACCAGTA
  CTCTACCATGGGGCATCCCAAGTGGGGTCCTCACCCATCCCAGCTACTGCAGCTCTGTAT
  TACTTTGTCATTTCCTGTTGTCTCACTCCTGAGGGCTCCTGCAGTAACTCTGTACTTCTC
  TATCTGCACACACAAAATGCCCAAGGCACTCACTGGGGAGGAAGCAAGGAAGCAAACAGT
  CTGAGAAAATGATGCAAGAAAATCAAATGGGAATCTGGGGACCCAACACAACATCCTGAA
  GATTATTAAAAGGAAAAGATGCTGATTGGTACATAAATCTTTTACATGGCCTTGGTCTAG
  AGGAGGCAGGCTTTTAGAATCATGTTTTGTTAATCCGCTTCACTAAATTGGACCTTCACA
  TATCTAAAAAGCTCTGAAGTGTTTGTATATTTGAAATACCTCAATAAAGAGAGAGCTCAT
  TGACTGTAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001002000.1 unedited
  TCGATTGTATACGACTCCTATAGGGCGGCAGGCTAATTCGGCACGAGGGGTAGAAGAAGG
  AAGTGTAGCGGGCCCTCAGATTCATCGCTACCCCGAGGCTAAGCGCCATGCCTCATATTG
  ACAACGATGTGAAACTGGACTTCAAGGATGTCCTTTTGAGGCCCAAACGCAGTACCCTTA
  AGTCTCGAAGTGAGGTGGATCTCACAAGATCCTTTTCATTTCGGAACTCAAAGCAGACAT
  ACTCTGGGGTTCCCATCATTGCTGCCAATATGGATACTGTGGGCACCTTTGAGATGGCCA
  AGGTTCTCTGTAAGTTCTCTCTCTTCTTTTTTGTCCATAAGCACTATAGCCTCGTTCAGT
  GGCAAGAGTTTGCTGGCCAGAATCCTGACTGTCTTGAGCATCTGGCTGCCAGCTCAGGCA
  CAGGCTCTTCTGACTTTGAGCAGCTGGAACAGATCCTGGAAGCTATTCCCCAGGTGAAGT
  ATATATGCCTGGATGTGGCAAATGGCTACTCTGAACACTTTGTTGAATTTGTAAAAGATG
  TACGGAAGCGCTTCCCCCAGCACACCATCATGGCAGGGAATGTGGTAACAGGAGAGATGG
  TAGAAGAGCTCATCCTTTCTGGGGCTGACATCATCAAAGTGGGAATTGGGCCAGGCTCTG
  TGTGTACTACTCGGAAGAAAACTGGAGTGGGGTATCCACAGCTCAGCGCAGTGATGGAGT
  GTGCAGATGCTGCTCATGGGCCTCAAAGGCCACATCATTTCAGATGGAGTTGCAGCTGTC
  CTGGGGATGTGGCCAAGCTTTTGGGGCAGGAGCTGACTTCTGATGCTGGGTGCATGCTGC
  TGGGCACAGTGAGTCAGTGGTGAGCTCATCGAGAGGATGGCAGAGTACAAGCCTCTTCAT
  GCATGACTTCTGAATGCATGATAGTATGCTGGGGGCGTGCTGATCGAAGCCTCGAGGCCG
  ACAGTGAAGA
• Restriction Sites: Please inquire
• ACCN: NM_001002000
• ORF Size: 1047 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001002000.1, NP_001002000.1
• RefSeq Size: 1956
• RefSeq ORF: 1047
• Locus ID: 51292
• Protein Families: Druggable Genome
• Protein Pathways: Purine metabolism
• Gene Summary: This gene encodes an enzyme that catalyzes the irreversible and NADPH-dependent reductive deamination of guanosine monophosphate (GMP) to inosine monophosphate (IMP). The protein also functions in the re-utilization of free intracellular bases and purine nucleosides. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2017]
  Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream in-frame start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus than isoform 1. Variants 2, 3, and 4 encode the same isoform (2).