ACSL5 (NM_016234) Human Untagged Clone

CAT#: SC321517

ACSL5 (untagged)-Human acyl-CoA synthetase long-chain family member 5 (ACSL5), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ACSL5
• Synonyms: ACS2; ACS5; FACL5
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_016234.3 CGAGCACGTTAGAAAGCCTGACATGGCCTGACTCGGGACAGCTCAGAGCAGGGCAGAACT
  GGGGACACTCTGGGCCGGCCTTCTGCCTGCATGGACGCTCTGAAGCCACCCTGTCTCTGG
  AGGAACCACGAGCGAGGGAAGAAGGACAGGGACTCGTGTGGCAGGAAGAACTCAGAGCCG
  GGAAGCCCCCATTCACTAGAAGCACTGAGAGATGCGGCCCCCTCGCAGGGTCTGAATTTC
  CTGCTGCTGTTCACAAAGATGCTTTTTATCTTTAACTTTTTGTTTTCCCCACTTCCGACC
  CCGGCGTTGATCTGCATCCTGACATTTGGAGCTGCCATCTTCTTGTGGCTGATCACCAGA
  CCTCAACCCGTCTTACCTCTTCTTGACCTGAACAATCAGTCTGTGGGAATTGAGGGAGGA
  GCACGGAAGGGGGTTTCCCAGAAGAACAATGACCTAACAAGTTGCTGCTTCTCAGATGCC
  AAGACTATGTATGAGGTTTTCCAAAGAGGACTCGCTGTGTCTGACAATGGGCCCTGCTTG
  GGATATAGAAAACCAAACCAGCCCTACAGATGGCTATCTTACAAACAGGTGTCTGATAGA
  GCAGAGTACCTGGGTTCCTGTCTCTTGCATAAAGGTTATAAATCATCACCAGACCAGTTT
  GTCGGCATCTTTGCTCAGAATAGGCCAGAGTGGATCATCTCCGAATTGGCTTGTTACACG
  TACTCTATGGTAGCTGTACCTCTGTATGACACCTTGGGACCAGAAGCCATCGTACATATT
  GTCAACAAGGCTGATATCGCCATGGTGATCTGTGACACACCCCAAAAGGCATTGGTGCTG
  ATAGGGAATGTAGAGAAAGGCTTCACCCCGAGCCTGAAGGTGATCATCCTTATGGACCCC
  TTTGATGATGACCTGAAGCAAAGAGGGGAGAAGAGTGGAATTGAGATCTTATCCCTATAT
  GATGCTGAGAACCTAGGCAAAGAGCACTTCAGAAAACCTGTGCCTCCTAGCCCAGAAGAC
  CTGAGCGTCATCTGCTTCACCAGTGGGACCACAGGTGACCCCAAAGGAGCCATGATAACC
  CATCAAAATATTGTTTCAAATGCTGCTGCCTTTCTCAAATGTGTGGAGCATGCTTATGAG
  CCCACTCCTGATGATGTGGCCATATCCTACCTCCCTCTGGCTCATATGTTTGAGAGGATT
  GTACAGGCTGTTGTGTACAGCTGTGGAGCCAGAGTTGGATTCTTCCAAGGGGATATTCGG
  TTGCTGGCTGACGACATGAAGACTTTGAAGCCCACATTGTTTCCCGCGGTGCCTCGACTC
  CTTAACAGGATCTACGATAAGGTACAAAATGAGGCCAAGACACCCTTGAAGAAGTTCTTG
  TTGAAGCTGGCTGTTTCCAGTAAATTCAAAGAGCTTCAAAAGGGTATCATCAGGCATGAT
  AGTTTCTGGGACAAGCTCATCTTTGCAAAGATCCAGGACAGCCTGGGCGGAAGGGTTCGT
  GTAATTGTCACTGGAGCTGCCCCCATGTCCACTTCAGTCATGACATTCTTCCGGGCAGCA
  ATGGGATGTCAGGTGTATGAAGCTTATGGTCAAACAGAATGCACAGGTGGCTGTACATTT
  ACATTACCTGGGGACTGGACATCAGGTCACGTTGGGGTGCCCCTGGCTTGCAATTACGTG
  AAGCTGGAAGATGTGGCTGACATGAACTACTTTACAGTGAATAATGAAGGAGAGGTCTGC
  ATCAAGGGTACAAACGTGTTCAAAGGATACCTGAAGGACCCTGAGAAGACACAGGAAGCC
  CTGGACAGTGATGGCTGGCTTCACACAGGAGACATTGGTCGCTGGCTCCCGAATGGAACT
  CTGAAGATCATCGACCGTAAAAAGAACATTTTCAAGCTGGCCCAAGGAGAATACATTGCA
  CCAGAGAAGATAGAAAATATCTACAACAGGAGTCAACCAGTGTTACAAATTTTTGTACAC
  GGGGAGAGCTTACGGTCATCCTTAGTAGGAGTGGTGGTTCCTGACACAGATGTACTTCCC
  TCATTTGCAGCCAAGCTTGGGGTGAAGGGCTCCTTTGAGGAACTGTGCCAAAACCAAGTT
  GTAAGGGAAGCCATTTTAGAAGACTTGCAGAAAATTGGGAAAGAAAGTGGCCTTAAAACT
  TTTGAACAGGTCAAAGCCATTTTTCTTCATCCAGAGCCATTTTCCATTGAAAATGGGCTC
  TTGACACCAACATTGAAAGCAAAGCGAGGAGAGCTTTCCAAATACTTTCGGACCCAAATT
  GACAGCCTGTATGAGCACATCCAGGATTAGGATAAGGTACTTAAGTACCTGCCGGCCCAC
  TGTGCACTGCTTGTGAGAAAATGGATTAAAAACTATTCTTACATTTAAAAAAAAAAAAAA
  AAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_016234.3 unedited
  GTCACTTTGTATACGACTCCTATAGGGCGGCCGGGAATTCGGCACGAGGCGAGCACGTTA
  GAAAGCCTGACATGGCCTGACTCGGGACAGCTCAGAGCAGGGCAGAACTGGGGACACTCT
  GGGCCGGCCTTCTGCCTGCATGGACGCTCTGAAGCCACCCTGTCTCTGGAGGAACCACGA
  GCGAGGGAAGAAGGACAGGGACTCGTGTGGCAGGAAGAACTCAGAGCCGGGAAGCCCCCA
  TTCACTAGAAGCACTGAGAGATGCGGCCCCCTCGCAGGGTCTGAATTTCCTGCTGCTGTT
  CACAAAGATGCTTTTTATCTTTAACTTTTTGTTTTCCCCACTTCCGACCCCGGCGTTGAT
  CTGCATCCTGACATTTGGAGCTGCCATCTTCTTGTGGCTGATCACCAGACCTCAACCCGT
  CTTACCTCTTCTTGACCTGAACAATCAGTCTGTGGGAATTGAGGGAGGAGCACGGAAGGG
  GGTTTCCCAGAAGAACAATGACCTAACAAGTTGCTGCTTCTCAGATGCCAAGACTATGTA
  TGAGGTTTTCCAAAGAGGACTCGCTGTGTCTGACAATGGGCCCTGCTTGGGATATAGAAA
  ACCAAACCAGCCCTACAGATGGCTATCTTACAAACAGGTGTCTGATAGAGCAGAGTACCT
  GGGTTCCTGTCTCTTGCATAAAGGTTATAAATCATCACCAGACCAGTTTGTCGGCATCTT
  TGCTCAGAATAGCCAGAGTGGATCATCTCCGATTGGCTTGTTACACGTACTCTATGGTAG
  CTGTACCTCTGTATGACACCTTGGGACCAGAAGCCATCGTACATATTGTCAACAGCTGAT
  ATTCGCCATGGTGATCTGGTGACACACCCCAAGCATGTGCTGATAGGGAATGTAAAGAAA
  GCTTCACCCGAGCCTGAAGTGAATCATCCTTATTG
• Restriction Sites: Please inquire
• ACCN: NM_016234
• ORF Size: 2220 bp
• Insert Size: 2339
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_016234.3, NP_057318.2
• RefSeq Size: 3372
• RefSeq ORF: 2220
• Locus ID: 51703
• Domains: AMP-binding
• Protein Families: Transmembrane
• Protein Pathways: Adipocytokine signaling pathway, Fatty acid metabolism, Metabolic pathways, PPAR signaling pathway
• Gene Summary: The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in uterus and spleen, and in trace amounts in normal brain, but has markedly increased levels in malignant gliomas. This gene functions in mediating fatty acid-induced glioma cell growth. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) encodes the longer isoform (a).