SKIP (INPP5K) (NM_016532) Human Untagged Clone

CAT#: SC321576

INPP5K (untagged)-Human inositol polyphosphate-5-phosphatase K (INPP5K), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: INPP5K
• Synonyms: MDCCAID; PPS; SKIP
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_016532.2 CCCAGATCCCGGGGTGCGCGGAGGGCGCGTCTCTGACGGAAGCCGGGGCGGACGGTCGGA
  GTCCGGAAGAAAAACAGTCCGCGACAGCTAGGCGCGTGAGACCGGCCGCCTGCAGGGCTG
  CTCTGGCCGGGACCCGCTGGCCGGGAGACGCGAACCTGCCGGACCACCGCGCGGGGACGA
  CGGCGGCCATGAGCTCGCGGAAGCTGAGCGGGCCGAAAGGCAGGAGGCTCAGCATACACG
  TCGTGACTTGGAACGTGGCTTCGGCAGCGCCCCCTCTAGATCTCAGTGACCTGCTTCAGC
  TGAACAACCGGAACCTCAATCTTGACATATATGTTATTGGTTTGCAGGAATTGAACTCTG
  GGATCATAAGCCTCCTTTCCGATGCTGCCTTTAATGACTCGTGGAGCAGTTTCCTCATGG
  ATGTGCTTTCCCCTCTGAGCTTCATCAAGGTCTCCCATGTCCGTATGCAGGGGATCCTCT
  TACTGGTCTTTGCCAAGTATCAGCATTTGCCCTATATCCAGATTCTGTCTACTAAATCCA
  CCCCCACTGGCCTGTTTGGGTACTGGGGGAACAAAGGTGGAGTCAACATCTGCCTGAAGC
  TTTATGGCTACTATGTCAGCATCATCAACTGCCACCTGCCTCCCCACATTTCCAACAATT
  ACCAGCGGCTGGAGCACTTTGACCGGATCCTGGAGATGCAGAATTGTGAGGGGCGAGACA
  TCCCAAACATCCTGGACCACGACCTCATTATCTGGTTTGGAGACATGAACTTTCGGATCG
  AGGACTTTGGGTTGCACTTTGTTCGGGAATCCATTAAAAATCGGTGCTACGGTGGCCTGT
  GGGAGAAGGACCAGCTCAGCATTGCCAAGAAACATGACCCGCTGCTCCGGGAGTTCCAGG
  AGGGCCGCCTACTCTTCCCGCCCACCTACAAGTTTGATAGGAACTCCAACGACTATGACA
  CCAGTGAGAAAAAACGCAAGCCTGCATGGACCGATCGCATCCTGTGGAGGCTGAAGCGGC
  AGCCCTGTGCTGGCCCCGACACTCCCATACCGCCGGCGTCACACTTCTCCTTGTCTCTGA
  GGGGCTACAGCAGCCACATGACGTACGGCATCAGCGACCACAAGCCTGTCTCCGGCACGT
  TCGACTTGGAGCTGAAGCCATTGGTGTCTGCTCCGCTGATCGTCCTGATGCCCGAGGACC
  TGTGGACCGTGGAAAATGACATGATGGTCAGCTACTCTTCAACCTCGGACTTCCCCAGCA
  GCCCGTGGGACTGGATTGGACTGTACAAGGTGGGGCTGCGGGACGTTAATGACTACGTGT
  CCTATGCCTGGGTCGGGGACAGCAAGGTCTCCTGCAGCGACAACCTGAACCAGGTTTACA
  TCGACATCAGCAATATCCCTACCACTGAAGATGAGTTTCTCCTCTGTTACTACAGCAACA
  GTCTGCGTTCTGTGGTGGGGATAAGCAGACCCTTCCAGATCCCGCCTGGCTCCTTGAGGG
  AGGACCCACTGGGTGAAGCACAGCCACAGATCTGAGCCAGGATGGGAGTGAATCCCAGGC
  GGAGGCCAGAGCTGGCAGCCAGCTCTGCCTTTCCACTGCCGGGAGTGCTGGGGGCCCAGC
  CTGGCCCCCTGAAGAGACAGCCAAGTGTCGTCCACATACTCCTCCCAGAGTGAGCTCTAA
  CCAGGCTCATTTGCTCTCTCCACTACTCATCTCTGGAATTAGCCGCTTAAATACAGGTTT
  TTGTTGCTGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAACTCGGG
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_016532.2 unedited
  GACGTTTGTATACGACTCCTATAGGGCGGCCGGGAATTCGGCACGAGGCCCAGATCCCGG
  GGTGCGCGGAGGGCGCGTCTCTGACGGAAGCCGGGGCGGACGGTCGGAGTCCGGAAGAAA
  AACAGTCCGCGACAGCTAGGCGCGTGAGACCGGCCGCCTGCAGGGCTGCTCTGGCCGGGA
  CCCGCTGGCCGGGAGACGCGAACCTGCCGGACCACCGCGCGGGGACGACGGCGGCCATGA
  GCTCGCGGAAGCTGAGCGGGCCGAAAGGCAGGAGGCTCAGCATACACGTCGTGACTTGGA
  ACGTGGCTTCGGCAGCGCCCCCTCTAGATCTCAGTGACCTGCTTCAGCTGAACAACCGGA
  ACCTCAATCTTGACATATATGTTATTGGTTTGCAGGAATTGAACTCTGGGATCATAAGCC
  TCCTTTCCGATGCTGCCTTTAATGACTCGTGGAGCAGTTTCCTCATGGATGTGCTTTCCC
  CTCTGAGCTTCATCAAGGTCTCCCATGTCCGTATGCAGGGGATCCTCTTACTGGTCTTTG
  CCAAGTATCAGCATTTGCCCTATATCCAGATTCTGTCTACTAAATCCACCCCCACTGGCC
  TGTTTGGGTACTGGGGGAACAAAGGTGGAGTCAACATCTGCCTGAAGCTTTATGGCTACT
  ATGTCAGCATCATCAACTGCCACCTGCCTCCCCACATTTCCAACAATTACCAGCGGCTGG
  AGCACTTTGACCGGATCCTGGAGATGCAGATTGTGAGGGCGAGACATCCCAAACATCCTG
  GACCACGACCTCATTATTCTGGTTTGGAAGACATGAACTTTCGATCGAGACTTTGGGTTG
  CACCTTTGTTCGGAATCCATAAAATCGTGCTACGTGGCTGGGGGGAGAAAGACAGCTCAG
  CATTGCAGAAACATGACCGCTGCTCCGGGAGTCAGGAGGGGCCGCCCTTACTCTTCCGGC
  CACACT
• Restriction Sites: Please inquire
• ACCN: NM_016532
• ORF Size: 1347 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_016532.2, NP_057616.2
• RefSeq Size: 2773
• RefSeq ORF: 1347
• Locus ID: 51763
• Domains: IPPc, Exo_endo_phos
• Protein Families: Druggable Genome, Phosphatase
• Protein Pathways: Inositol phosphate metabolism, Insulin signaling pathway, Metabolic pathways, Phosphatidylinositol signaling system
• Gene Summary: This gene encodes a protein with 5-phosphatase activity toward polyphosphate inositol. The protein localizes to the cytosol in regions lacking actin stress fibers. It is thought that this protein may negatively regulate the actin cytoskeleton. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008]
  Transcript Variant: This variant (1) encodes the longer isoform of this protein.