BMP5 (NM_021073) Human Untagged Clone

CAT#: SC321699

BMP5 (untagged)-Human bone morphogenetic protein 5 (BMP5)


  "NM_021073" in other vectors (6)

Reconstitution Protocol

USD 310.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol BMP5
Synonyms MGC34244
Vector pCMV6-AC
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>OriGene sequence for NM_021073.2 CTCTTGAAGAGGGCTGGTATATTTGTGCCTGCTGGAGGTGGAATTAACAGTAAGAAGGAG
AAAGGGATTGAATGGACTTACAGGAAGGATTTCAAGTAAATTCAGGGAAACACATTTACT
TGAATAGTACAACCTAGAGTATTATTTTACACTAAGACGACACAAAAGATGTTAAAGTTA
TCACCAAGCTGCCGGACAGATATATATTCCAACACCAAGGTGCAGATCAGCATAGATCTG
TGATTCAGAAATCAGGATTTGTTTTGGAAAGAGCTCAAGGGTTGAGAAGAACTCAAAAGC
AAGTGAAGATTACTTTGGGAACTACAGTTTATCAGAAGATCAACTTTTGCTAATTCAAAT
ACCAAAGGCCTGATTATCATAAATTCATATAGGAATGCATAGGTCATCTGATCAAATAAT
ATTAGCCGTCTTCTGCTACATCAATGCAGCAAAAACTCTTAACAACTGTGGATAATTGGA
AATCTGAGTTTCAGCTTTCTTAGAAATAACTACTCTTGACATATTCCAAAATATTTAAAA
TAGGACAGGAAAATCGGTGAGGATGTTGTGCTCAGAAATGTCACTGTCATGAAAAATAGG
TAAATTTGTTTTTTCAGCTACTGGGAAACTGTACCTCCTAGAACCTTAGGTTTTTTTTTT
TTTTAAGAGGACAAGAAGGACTAAAAATATCAACTTTTGCTTTTGGACAAAAATGCATCT
GACTGTATTTTTACTTAAGGGTATTGTGGGTTTCCTCTGGAGCTGCTGGGTTCTAGTGGG
TTATGCAAAAGGAGGTTTGGGAGACAATCATGTTCACTCCAGTTTTATTTATAGAAGACT
ACGGAACCACGAAAGACGGGAAATACAAAGGGAAATTCTCTCTATCTTGGGTTTGCCTCA
CAGACCCAGACCATTTTCACCTGGAAAACAAGCGTCCTCTGCACCTCTCTTTATGCTGGA
TCTCTACAATGCCATGACCAATGAAGAAAATCCTGAAGAGTCGGAGTACTCAGTAAGGGC
ATCCTTGGCAGAAGAGACCAGAGGGGCAAGAAAGGGATACCCAGCCTCTCCCAATGGGTA
TCCTCGTCGCATACAGTTATCTCGGACGACTCCTCTGACCACCCAGAGTCCTCCTCTAGC
CAGCCTCCATGATACCAACTTTCTGAATGATGCTGACATGGTCATGAGCTTTGTCAACTT
AGTTGAAAGAGACAAGGATTTTTCTCACCAGCGAAGGCATTACAAAGAATTTCGATTTGA
TCTTACCCAAATTCCTCATGGAGAGGCAGTGACAGCAGCTGAATTCCGGATATACAAGGA
CCGGAGCAACAACCGATTTGAAAATGAAACAATTAAGATTAGCATATATCAAATCATCAA
GGAATACACAAATAGGGATGCAGATCTGTTCTTGTTAGACACAAGAAAGGCCCAAGCTTT
AGATGTGGGTTGGCTTGTCTTTGATATCACTGTGACCAGCAATCATTGGGTGATTAATCC
CCAGAATAATTTGGGCTTACAGCTCTGTGCAGAAACAGGGGATGGACGCAGTATCAACGT
AAAATCTGCTGGTCTTGTGGGAAGACAGGGACCTCAGTCAAAACAACCATTCATGGTGGC
CTTCTTCAAGGCGAGTGAGGTACTTCTTCGATCCGTGAGAGCAGCCAACAAACGAAAAAA
TCAAAACCGCAATAAATCCAGCTCTCATCAGGACTCCTCCAGAATGTCCAGTGTTGGAGA
TTATAACACAAGTGAGCAAAAACAAGCCTGTAAGAAGCACGAACTCTATGTGAGCTTCCG
GGATCTGGGATGGCAGGACTGGATTATAGCACCAGAAGGATACGCTGCATTTTATTGTGA
TGGAGAATGTTCTTTTCCACTTAACGCCCATATGAATGCCACCAACCACGCTATAGTTCA
GACTCTGGTTCATCTGATGTTTCCTGACCACGTACCAAAGCCTTGTTGTGCTCCAACCAA
ATTAAATGCCATCTCTGTTCTGTACTTTGATGACAGCTCCAATGTCATTTTGAAAAAATA
TAGAAATATGGTAGTACGCTCATGTGGCTGCCACTAATATTAAATAATATTGATAATAAC
AAAAAGATCTGTATTAAGGTTTATGGCTGCAATAAAAAGCATACTTTCAGACAAACGGGG
AATTTCCTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Restriction Sites Please inquire     
ACCN NM_021073
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_021073.2, NP_066551.1
RefSeq Size 2207 bp
RefSeq ORF 1365 bp
Locus ID 653
Cytogenetics 6p12.1
Domains TGFb_propeptide, TGF-beta
Protein Families Adult stem cells, Cancer stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Secreted Protein, Stem cell relevant signaling - TGFb/BMP signaling pathway
Protein Pathways Hedgehog signaling pathway, TGF-beta signaling pathway
Gene Summary 'This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Polymorphisms in this gene may be associated with osteoarthritis in human patients. This gene is differentially regulated in multiple human cancers. This gene encodes distinct protein isoforms that may be similarly proteolytically processed. [provided by RefSeq, Jul 2016]'
Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).

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