Alpha 2 Antiplasmin (SERPINF2) (NM_000934) Human Untagged Clone

CAT#: SC321810

SERPINF2 (untagged)-Human serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 (SERPINF2), transcript variant 1


  "NM_000934" in other vectors (4)

Reconstitution Protocol

USD 830.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol SERPINF2
Synonyms A2AP; AAP; ALPHA-2-PI; API; PLI
Vector pCMV6-AC
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>OriGene sequence for NM_000934.3 GGGACTTGAAAAACTGGAGCCTGTTCTTGGCAAGAAGATTCTAATGCCCAGGAACATGGT
GCTGCTCTGGGGGCTCCTGGTGCTCAGCTGGTCCTGCCTGCAAGGCCCCTGCTCCGTGTT
CTCCCCTGTGAGCGCCATGGAGCCCTTGGGCCGGCAGCTAACTAGCGGGCCGAACCAGGA
GCAGGTGTCCCCACTTACCCTCCTCAAGTTGGGCAACCAGGAGCCTGGTGGCCAGACTGC
CCTGAAGAGTCCCCCAGGAGTCTGCAGCAGAGACCCCACCCCAGAGCAGACCCACAGGCT
GGCCCGGGCCATGATGGCCTTCACTGCCGACCTGTTCTCCCTGGTGGCTCAAACGTCCAC
CTGCCCCAACCTCATCCTGTCACCCCTGAGTGTGGCCCTGGCGCTGTCTCACCTGGCACT
AGGTGCTCAGAACCACACGTTGCAGAGGCTGCAACAGGTGCTGCACGCAGGCTCAGGGCC
CTGCCTCCCCCATCTGCTGAGCCGCCTCTGCCAGGACCTGGGCCCCGGCGCGTTCCGACT
GGCTGCCAGGATGTACCTGCAGAAAGGATTTCCCATCAAAGAAGATTTCCTGGAACAATC
CGAACAGCTATTTGGGGCAAAGCCCGTGAGCCTGACGGGAAAGCAGGAAGATGACCTGGC
AAACATCAACCAATGGGTGAAGGAGGCCACGGAGGGGAAGATTCAGGAATTCCTCTCTGG
GCTGCCGGAAGACACCGTGTTGCTTCTCCTCAACGCCATCCACTTCCAGGGTTTCTGGAG
GAACAAGTTTGACCCGAGCCTTACCCAGAGAGACTCCTTCCACCTGGACGAGCAGTTCAC
GGTGCCCGTGGAAATGATGCAGGCCCGCACGTACCCGCTGCGCTGGTTCTTGCTGGAGCA
GCCTGAGATCCAGGTGGCTCATTTCCCCTTTAAGAACAACATGAGCTTTGTGGTCCTTGT
ACCCACCCACTTTGAATGGAACGTGTCCCAGGTACTGGCCAACCTGAGTTGGGACACCCT
GCACCCACCTCTGGTGTGGGAGAGGCCCACCAAGGTCCGGCTGCCTAAGCTGTATCTGAA
ACACCAAATGGACCTGGTGGCCACCCTCAGCCAGCTGGGCCTGCAGGAGTTGTTCCAGGC
CCCAGACCTGCGTGGGATCTCCGAGCAGAGCCTGGTGGTGTCCGGCGTGCAGCATCAGTC
CACCCTGGAGCTCAGCGAGGTCGGCGTGGAGGCGGCGGCGGCCACCAGCATTGCCATGTC
CCGCATGTCCCTGTCCTCCTTCAGCGTGAACCGCCCCTTCCTCTTCTTCATCTTCGAGGA
CACCACAGGCCTTCCCCTCTTCGTGGGCAGCGTGAGGAACCCCAACCCCAGTGCACCGCG
GGAGCTCAAGGAACAGCAGGATTCCCCGGGCAACAAGGACTTCCTCCAGAGCCTGAAAGG
CTTCCCCCGCGGAGACAAGCTTTTCGGCCCTGACTTAAAACTTGTGCCCCCCATGGAGGA
GGATTACCCCCAGTTTGGCAGCCCCAAGTGAGGGGCCGTGGCTGTGGCATCCAGAGTCCC
TGCCTGGACCAGCCTCTCCACTCATGTGACTCTTTCCAACCTGCTTTGTGGCACTGGGGC
AGGGGCCGGGGGCAGTCTGAGAGAGGCCATTCTTTCCCAACACCTCTTGGGGAGTTTAGG
GTGGGGGGGGGCGCGGCTGGGAGGAGGGCAGGCATCGGGGAGCCGGGAGCCTGACCCTCA
TCTTTCTTCCAAACAGGCTCAGAGGGTGTCCTGCACCGGGGCCTGGGCAGGAGGGAGGTG
CTTCTAGTTCTGCCAGGAGACAGGTTAGCTGCTCCCCACGTCAGCTGGGACACCCCGACT
TTTGTTTACCAGAGAAAAAGGGAGGGGGAGAGGGCTGCCTTTGGACTTGTCCCGGGACAC
CTAGGCTAGGGTGGGGAGAGACGGGCCCTGGTGGTGGCTCGGGAGGCGAAGCGTTGTCCT
CAGCCCCGCGTGGAACTCGTGTCTGGCACAGCCTGGCTGTGGCCTAACCTGCCGAGAGTC
CATCAGCCTCCATCCTACCCCCTGTGCCTTGTCACGCCAGACTTCCCACGGCTCCTCGAG
ATCCCAACACTGCCAGCATTTCCCTTCCTTCCTCTCCTGTCTCCCTCCTCTGCCCGGGAG
CTCAGGAACCGAGGCAGGGAAGGATCCCATGAGCTCCTTAAGGCTCTTTTGTAAGGTTTT
TGTAGTGATTTTTATGCCACCTGAATAAAGAATGAATGGGCAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAA
Restriction Sites Please inquire     
ACCN NM_000934
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_000934.3, NP_000925.2
RefSeq Size 2284 bp
RefSeq ORF 1476 bp
Locus ID 5345
Cytogenetics 17p13.3
Domains SERPIN
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Complement and coagulation cascades
Gene Summary 'This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]'
Transcript Variant: This variant (1) represents the longest transcript. Both variants 1 and 2 encode the same isoform (a).

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