PILRB (NM_013440) Human Untagged Clone

CAT#: SC321885

PILRB (untagged)-Human paired immunoglobin-like type 2 receptor beta (PILRB), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PILRB
• Synonyms: FDFACT1; FDFACT2
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_013440.3 GGAAGTCTCCACCCCTGGGAGGCAGAAGCCAGGCATAGCGCGCTGGCTAGGACTCCAGTA
  CCGTGAAGGGAGGCAGTGAGAGCAGACATCTGTGCCTCATTCCTGATCTCAAGGGGAAAG
  CAAGAACAAGGGAGGCTTCCTCAGGATCTCGAACCTGCGGAAGGAGGACCAGTCTGTGTA
  CTTCTGCCAAGTCCAGCTGGACATACAGATCAGGGAGGCTGTCGTGGCAGTCCATCAAGG
  GGACCCACCTCACCATCACCCAGGCCCTCAGGCAGCCCCTCCACAGGGCCCCTCTCCTGC
  CTGGACAGCTCTGCTGGTCTCCCCGTCCCCTGGAGAAGAACAAGGCCATGGGTCGGCCCC
  TGCTGCTGCCCCTGCTGCTCCTGCTGCAGCCGCCAGCATTTCTGCAGCCTGGTGGCTCCA
  CAGGATCTGGTCCAAGCTACCTTTATGGGGTCACTCAACCAAAACACCTCTCAGCCTCCA
  TGGGTGGCTCTGTGGAAATCCCCTTCTCCTTCTATTACCCCTGGGAGTTAGCCATAGTTC
  CCAACGTGAGAATATCCTGGAGACGGGGCCACTTCCACGGGCAGTCCTTCTACAGCACAA
  GGCCGCCTTCCATTCACAAGGATTATGTGAACCGGCTCTTTCTGAACTGGACAGAGGGTC
  AGGAGAGCGGCTTCCTCAGGATCTCAAACCTGCGGAAGGAGGACCAGTCTGTGTATTTCT
  GCCGAGTCGAGCTGGACACCCGGAGATCAGGGAGGCAGCAGTTGCAGTCCATCAAGGGGA
  CCAAACTCACCATCACCCAGGCTGTCACAACCACCACCACCTGGAGGCCCAGCAGCACAA
  CCACCATAGCCGGCCTCAGGGTCACAGAAAGCAAAGGGCACTCAGAATCATGGCACCTAA
  GTCTGGACACTGCCATCAGGGTTGCATTGGCTGTCGCTGTGCTCAAAACTGTCATTTTGG
  GACTGCTGTGCCTCCTCCTCCTGTGGTGGAGGAGAAGGAAAGGTAGCAGGGCGCCAAGCA
  GTGACTTCTGACCAACAGAGTGTGGGGAGAAGGGATGTGTATTAGCCCCGGAGGACGTGA
  TGTGAGACCCGCTTGTGAGTCCTCCACACTCGTTCCCCATTGGCAAGATACATGGAGAGC
  ACCCTGAGGACCTTTAAAAGGCAAAGCCGCAAGGCAGAAGGAGGCTGGGTCCCTGAATCA
  CCGACTGGAGGAGAGTTACCTACAAGAGCCTTCATCCAGGAGCATCCACACTGCAATGAT
  ATAGGAATGAGGTCTGAACTCCACTGAATTAAACCACTGGCATTTGGGGGCTGTTTATTA
  TAGCAGTGCAAAGAGTTCCTTTATCCTCCCCAAGGATGGAAAAATACAATTTATTTTGCT
  TACCATACACCCCTTTTCTCCTCGTCCACATTTTCCAATCTGTATGGTGGCTGTCTTCTA
  TGGCAGAAGGTTTTGGGGAATAAATAGCGTGAAATGCTAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_013440.3 unedited
  GTGCATTTTGTATACGACTCCTATAGGGCGGCTGGCGATCGCGGCGCGCCGGTACCGGTC
  CGGAATTCCCGGGATGGAAGTCTCCACCCCTGGGAGGCAGAAGCCAGGCATAGCGCGCTG
  GCTAGGACTCCAGTACCGTGAAGGGAGGCAGTGAGAGCAGACATCTGTGCCTCATTCCTG
  ATCTCAAGGGGAAAGCAAGAACAAGGGAGGCTTCCTCAGGATCTCGAACCTGCGGAAGGA
  GGACCAGTCTGTGTACTTCTGCCAAGTCCAGCTGGACATACAGATCAGGGAGGCTGTCGT
  GGCAGTCCATCAAGGGGACCCACCTCACCATCACCCAGGCCCTCAGGCAGCCCCTCCACA
  GGGCCCCTCTCCTGCCTGGACAGCTCTGCTGGTCTCCCCGTCCCCTGGAGAAGAACAAGG
  CCATGGGTCGGCCCCTGCTGCTGCCCCTGCTGCTCCTGCTGCAGCCGCCAGCATTTCTGC
  AGCCTGGTGGCTCCACAGGATCTGGTCCAAGCTACCTTTATGGGGTCACTCAACCAAAAC
  ACCTCTCAGCCTCCATGGGTGGCTCTGTGGAAATCCCCTTCTCCTTCTATTACCCCTGGG
  AGTTAGCCATAGTTCCCAACGTGAGAATATCCTGGAGACGGGGCCACTTCCACGGGCAGT
  CCTTCTACAGCACAAGCCGCCTTCCATTCACAAAGATTATGTGAACCGGCTCTTTCTGAA
  CTGGACAGAGGGTCAGGAGAGCGGCTTCCTCAGGATCTCAAACCTGCGGAAGGAGGACCA
  GTCTGTGTATTTCTGCCGAGTCGAGCTGGACACCCGGAGATCAGGAGCAGCAGTTGCAGT
  CCATCAAGGGGACCAAACTCACCATCACCCAGGCTGTCACACCACCCCCCCCTGGAGGCC
  CAGCAGCACACCACCATAGCGCTCAGGTCACAAGAAGCAAAGGCACTCAGAATCATGCAC
  CTTAGTCTGAACCTGCATCAGGTGCATGGCTGGTGCGCGTTGGCCTCAAAACTGT
• Restriction Sites: Please inquire
• ACCN: NM_013440
• ORF Size: 684 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_013440.3, NP_038468.3
• RefSeq Size: 3632
• RefSeq ORF: 684
• Locus ID: 29990
• Domains: IG
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: The paired immunoglobin-like type 2 receptors consist of highly related activating and inhibitory receptors that are involved in the regulation of many aspects of the immune system. The paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This gene encodes the activating member of the receptor pair and contains a truncated cytoplasmic tail relative to its inhibitory counterpart (PILRA), that has a long cytoplasmic tail with immunoreceptor tyrosine-based inhibitory (ITIM) motifs. This gene is thought to have arisen from a duplication of the inhibitory PILRA gene and evolved to acquire its activating function. [provided by RefSeq, Jun 2013]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Variants 1 and 3 encode the same isoform (a).