PWWP3A (NM_032853) Human Untagged Clone

CAT#: SC322055

MUM1 (untagged)-Human melanoma associated antigen (mutated) 1 (MUM1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PWWP3A
• Synonyms: EXPAND1; HSPC211; MUM-1; MUM1
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_032853, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGATGGCGGATGCCAAGTATGTCCTCTGCCGATGGGAAAAGCGATTATGGCCTGCGAAGGTTTTGGCCC
  GAACCGCGACTTCAACAAAAAATAAGAGAAGAAAGGAATATTTTCTAGCTGTGCAAATCCTCTCTCTAGA
  GGAAAAAATTAAGGTGAAAAGCACTGAAGTTGAGATCCTAGAGAAGTCTCAAATTGAAGCCATTGCTTCC
  TCGTTAGCCTCACAGAATGAGGTTCCTGCGGCACCCCTGGAAGAACTGGCCTACAGACGGTCGCTTCGCG
  TGGCTCTGGACGTTCTGAGCGAGGGCTCGATTTGGAGTCAAGAAAGCTCTGCAGGGACAGGTAGAGCTGA
  CCGGTCTCTGCGAGGGAAGCCCATGGAGCATGTCTCCTCGCCCTGTGATTCGAACTCCTCATCTCTTCCC
  CGCGGAGACGTGTTGGGCAGTTCCAGACCTCACAGGAGGAGGCCATGTGTGCAACAAAGCCTGTCAAGTT
  CGTTCACTTGTGAAAAGGACCCCGAGTGCAAAGTGGACCACAAGAAGGGGCTCAGGAAAAGTGAAAACCC
  AAGAGGCCCGTTGGTCCTCCCAGCTGGAGGTGGTGCCCAAGATGAGAGTGGGTCCAGAATCCACCACAAA
  AATTGGACTCTTGCAAGTAAGAGGGGAGGAAACTCAGCGCAGAAGGCTAGCTTGTGCCTGAATGGATCTT
  CCCTTTCAGAGGACGACACGGAGAGAGACATGGGGAGCAAAGGAGGCAGCTGGGCAGCCCCGTCCTTGCC
  CTCCGGGGTCAGGGAGGACGATCCCTGTGCCAACGCTGAGGGACACGACCCCGGTCTGCCGTTGGGCAGC
  CTCACTGCGCCCCCAGCCCCTGAGCCCTCGGCCTGCTCAGAGCCTGGAGAATGCCCTGCGAAAAAGAGGC
  CGCGCCTGGATGGCAGCCAAAGGCCGCCTGCCGTGCAGCTGGAGCCCATGGCAGCAGGGGCCGCACCATC
  CCCCGGGCCGGGGCCAGGGCCCAGAGAGTCTGTGACCCCGCGCAGCACCGCCAGGCTGGGCCCGCCTCCC
  TCCCACGCCTCTGCGGATGCAACCAGATGTCTTCCTTGCCCGGATTCCCAGAAGCTGGAGAAAGAGTGCC
  AGTCTTCCGAAGAGTCCATGGGGTCTAATTCCATGCGTTCTATCCTGGAGGAAGACGAGGAAGACGAGGA
  GCCACCAAGAGTCCTTTTATACCACGAACCACGTTCGTTTGAAGTAGGAATGCTAGTCTGGCATAAACAT
  AAAAAATACCCCTTCTGGCCAGCAGTGGTCAAAAGCGTCAGGCAGAGAGATAAGAAAGCAAGTGTGCTAT
  ACATCGAAGGACACATGAACCCGAAAATGAAAGGTTTCACAGTGTCTCTTAAAAGTTTAAAGCACTTTGA
  TTGTAAAGAGAAACAGACGCTTCTGAATCAAGCCAGGGAGGACTTCAACCAGGACATCGGCTGGTGTGTC
  TCCCTCATCACCGACTACAGGGTCCGGTTAGGCTGCGGGTCTTTTGCTGGCTCTTTCCTGGAATATTACG
  CGGCTGATATAAGCTATCCTGTCCGAAAATCCATCCAGCAGGACGTCTTGGGGACCAAGCTTCCTCAACT
  GAGCAAGGGGAGCCCCGAGGAGCCCGTGGTGGGGTGCCCCCTGGGGCAGAGGCAGCCCTGCCGGAAAATG
  CTCCCCGACCGCTCGCGGGCCGCCCGGGACCGGGCCAACCAGAAGCTGGTGGAGTACATTGTGAAGGCCA
  AGGGCGCGGAGAGCCACCTGCGGGCCATCCTAAAGAGCAGGAAGCCATCTCGCTGGCTGCAGACCTTCCT
  GAGCTCCAGCCAGTACGTGACCTGTGTGGAGACCTACCTGGAGGATGAGGGGCAGCTGGACCTGGTGGTG
  AAGTACCTGCAGGGCGTCTACCAGGAGGTGGGGGCCAAGGTGCTCCAGCGCACCAACGGCGACCGGATCC
  GGTTCATTCTGGACGTGCTTCTGCCCGAGGCCATCATCTGTGCGATCTCTGCGGTGGACGAGGTGGACTA
  CAAGACGGCTGAGGAGAAGTACATCAAGGGGCCTTCGCTGAGCTACCGGGAAAAAGAAATATTTGACAAC
  CAGCTCCTTGAAGAGCGGAACCGGCGCCGTCGGTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for SC322055 unedited
  GTGGCGATTGTATACGACTCCTATAGGGCGGCGCGGCGATCGCGGCGCGCCGGTACCGGT
  CCGGAATTCCCGGGATATCGTCGACCCACGCGTCCGGGCGGAGGCGGACACATTGGCGTG
  AGACCTGGGAGTACGTTGTGCCAAATCATTGCCACTTGCCACATGAGTGTAAATGATGGC
  GGATGCCAAGTATGTCCTCTGCCGATGGGAAAAGCGATTATGGCCTGCGAAGGTTTTGGC
  CCGAACCGCGACTTCAACAAAAAATAAGAGAAGAAAGGAATATTTTCTAGCTGTGCAAAT
  CCTCTCCCTAGAGGAAAAAATTAAGGTGAAAAGCACTGAGGGGTGAGATCCTAGAGAAGT
  CTCAAATTGAAGCCATTGCTTCCTCGTTAGCCTCACAGAATGAGGTTCCTGCGGCACCCC
  TGGAAGAACTGGCCTACAGACGGTCGCTTCGCGTGGCTCTGGACGTTCTGAGCGAGGGCT
  CGATTTGGAGTCAAGAAAGCTCTGCAGGGACAGGTAGAGCTGACCGGTCTCTGCGAGGGA
  AGCCCATGGAGCATGTCTCCTCGCCCTGTGATTCGAACTCCTCATCTCTTCCCCGCGGAG
  ACGTGTTGGGCAGTTCCAGACCTCACAGGAGGAGGCCATGTGTGCAACAAAGCCTGTCAA
  GTTCGTTCACTTGTGAAAAGGACCCCGAGTGCAAAGTGGACCACAAGAATGGGCTCAGAA
  AAGTGAAAACCCAAGAGGCCCGTTGGTCCTCCCAGCTGGAGGTGGTGCCCAAGGATGAGA
  GTGGGTCCAGGATTCACCACCAAAATTGGACCTTCTTGCCAGTAGAAGGGTAAGATCTCA
  GCGCAGAAGGCTAGCTGGGCCTGAATGGAATCTTCCTTCGGAAGGACGACACGGAGGAGA
  AACATGGGGGAGCCAAGGGAGGCCAGCTGGGCAGCCCGTTCCTTGGCCTTCTGGGATCAG
  TGAGACCATTCCTGTGCCAGCTTGAGGTAACACACACCGGTTCTCGACTGTGGGTGGCA
• Restriction Sites: Please inquire
• ACCN: NM_032853
• ORF Size: 2136 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_032853.2, NP_116242.2
• RefSeq Size: 4179
• RefSeq ORF: 2136
• Locus ID: 84939
• Gene Summary: Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage. [UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (1) lacks an alternate coding exon compared to variant 4. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a. Variants 1 and 3 both encode the same isoform (b). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. CCDS Note: The coding region has been updated to shorten the N-terminus to one that is more supported by conservation.