AP4S1 (NM_007077) Human Untagged Clone

CAT#: SC322208

AP4S1 (untagged)-Human adaptor-related protein complex 4, sigma 1 subunit (AP4S1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: AP4S1
• Synonyms: AP47B; CLA20; CLAPS4; CPSQ6; SPG52
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for SC322208 CGCGTAGCCAGTGAAGGTTGGGGAGCAAGCTTATGCGGGAAAGAGGGAGGGGGACTCCAG
  GAAAAGCCGTTGAGAGGACCATCACAACCTGAGCAGCACAGGTTCCAGTTACAGCCATCC
  CTTGTCATAACTTTTGAACTGTATTTGGAAAAATACTGGCCAGGAAAGAAAAATGATAAA
  ATTTTTCCTCATGGTGAATAAACAAGGGCAGACTCGACTTTCTAAGTACTATGAACATGT
  GGATATTAATAAGCGTACACTTCTGGAAACAGAAGTCATAAAGAGCTGTCTCTCTCGATC
  CAATGAACAATGCTCTTTCATTGAATATAAGGATTTTAAGCTGATATATCGGCAGTATGC
  AGCTCTCTTCATTGTGGTTGGAGTTAATGACACTGAGAACGAGATGGCTATTTATGAATT
  CATTCATAACTTTGTGGAAGTTTTAGATGAGTATTTCAGCCGAGTGAGTGAATTAGATGT
  ATCCTTTTTCAATACTGTTTTCCACAGTACTTGGCAAATGCACTCTGGTCCTTATCAGGA
  ACCAATTGATGAACTTCCCAAAATATGCTCAGCCCTGGAGCCCCAGCAGACTTGCTTTTC
  TCCAGACAGTTCATCATTCAAAGGAGCTGCCTCCACCACCCCCATCTACTGAATAGCCAG
  GGGAGGGCACCAATGAACAGCACAGTATGGGAGACACACCAACTACTCTTCAAATCAGTG
  CGTACCTGCTCTACGCGTGAAGGTACAGAAAACCTCCACGGCCTTTTCAGTATTTGGTGC
  CTTTAAAGAGGCCTAAGGACTTAGTTTATTTGGGCTAGACTGGAATGCAGCAGTACTGCC
  TTCAGGCCTGGACAGCCAGGGGCTCCTCGGGCCCTGTGCTCTAGAAGGCCCATTCTATGT
  CTGCTTCGCCAGCACCCTTTCCCCATCATGGGGCAGATGCCCACCAGCCCTCACTATCTA
  CTGCTTGACCATCCTCTGACTTCCTGGGCCCCTAGAATTTATAAGGTCCCTAGATATCCC
  AGAACCTGCCACCATGGCCTCTGCAAGCCTCTCCTCCACCTTCACCCCAAGACTAGGGGC
  AGGAATGATAAGAAGGCTGGGTGGTAGCTGGGATGTCCCACCTACGTGCCTGGGGAGAGA
  AGCAAGAGCAGGCTGGAGTCTCTACTTTGTATTCTTGTGAGGCACAAATATAGGCTAGAA
  TCCAGGCCCCACAAATATAGGCTAGAATCCGGAATGTTTTCTTGATTTAAAGACATCTTT
  AGACCGGGCACAGTGGCTCACGCCAGTAATCCCAGCACTTTGGAGGGCTGAAGCAGGAGG
  ATTGCTTGAGGCCGGGAGTTTGAGACCAGCCTGGGCAACATGGGGAGACCCAGTCTCTAC
  AAAAAAATTTAAAAAGCCAGGCATTGGTGGTGTGTGCCTATAGTCCCAACTACTAGGGAG
  GCTGAGGTGGGAGGATCACTTGAGCCTGGGGGACTGAGGCTGCAGTGAGCCATGATTGTG
  CTACTGCACTCCAATCTGGCAACAGAGCGAGACCTTGTCTTTAAAAATAAAAATAAAAAC
  ATCTTTACAACAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for SC322208 unedited
  GGCTACTTTGTATACGACTCCTATAGGGCGGCCGGCGATCGCGGCGCGCCGGTACCGGTC
  CGGAATTCCCGGGATATCGTCGACCCACGCGTCCGCGCGTAGCCAGTGAAGGTTGGGGAG
  CAAGCTTATGCGGGAAAGAGGGAGGGGGACTCCAGGAAAAGCCGTTGAGAGGACCATCAC
  AACCTGAGCAGCACAGGTTCCAGTTACAGCCATCCCTTGTCATAACTTTTGAACTGTATT
  TGGAAAAATACTGGCCAGGAAAGAAAAATGATAAAATTTTTCCTCATGGTGAATAAACAA
  GGGCAGACTCGACTTTCTAAGTACTATGAACATGTGGATATTAATAAGCGTACACTTCTG
  GAAACAGAAGTCATAAAGAGCTGTCTCTCTCGATCCAATGAACAATGCTCTTTCATTGAA
  TATAAGGATTTTAAGCTGATATATCGGCAGTATGCAGCTCTCTTCATTGTGGTTGGAGTT
  AATGACACTGAGAACGAGATGGCTATTTATGAATTCATTCATAACTTTGTGGAAGTTTTA
  GATGAGTATTTCAGCCGAGTGAGTGAATTAGATGTATCCTTTTTCAATACTGTTTTCCAC
  AGTACTTGGCAAATGCACTCTGGTCCTTATCAGAACCAATTGATGAACTTCCCAAAATAT
  GCTCAGCCCTGGAGCCCCAGCAGACTTGCTTTTCTCCAGACAGTTCATCATTCAAAGGAG
  CTGCCTCCACCACCCCCCATCTACTGAATAGCCAGGGGAGGGCACCAATGAACAGCACAG
  TATGGGAGACACACCAACTACTCTTCAAATCAGTGCGTACCTGCTCTACGCGTGAAGTAC
  AGAAAAACCTCCACGCTTTCAGTATTTGGTGCTTAAAGAGCCTAGACTAGTTTATTTGGC
  TAAGACTGGAATGCAGCAGTACTTGCCCTTCAGG
• Restriction Sites: Please inquire
• ACCN: NM_007077
• ORF Size: 480 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_007077.2, NP_009008.2
• RefSeq Size: 1587
• RefSeq ORF: 480
• Locus ID: 11154
• Domains: Clat_adaptor_s
• Protein Pathways: Lysosome
• Gene Summary: This gene encodes a member of the adaptor complexes small subunit protein family. These proteins are components of the heterotetrameric adaptor protein complexes, which play important roles in the secretory and endocytic pathways by mediating vesicle formation and sorting of integral membrane proteins. The encoded protein is the small subunit of adaptor protein complex-4, which is associated with both clathrin- and nonclathrin-coated vesicles. Mutations in this gene are associated with spastic quadriplegic cerebral palsy-6. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 6. [provided by RefSeq, Dec 2011]
  Transcript Variant: This variant (1) encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.